0000000000747522
AUTHOR
E. Young
Impact of clinical phenotypes on management and outcomes in European atrial fibrillation patients: a report from the ESC-EHRA EURObservational Research Programme in AF (EORP-AF) General Long-Term Registry
Abstract Background Epidemiological studies in atrial fibrillation (AF) illustrate that clinical complexity increase the risk of major adverse outcomes. We aimed to describe European AF patients’ clinical phenotypes and analyse the differential clinical course. Methods We performed a hierarchical cluster analysis based on Ward’s Method and Squared Euclidean Distance using 22 clinical binary variables, identifying the optimal number of clusters. We investigated differences in clinical management, use of healthcare resources and outcomes in a cohort of European AF patients from a Europe-wide observational registry. Results A total of 9363 were available for this analysis. We identified three …
Sensitivity Analysis of the MASLWR Helical Coil Steam Generator Using TRACE
Accurate simulation of transient system behavior of a nuclear power plant is the goal of systems code calculations, and the evaluation of a code's calculation accuracy is accomplished by assessment and validation against appropriate system data. These system data may be developed either from a running system prototype or from a scaled model test facility, and characterize the thermal hydraulic phenomena during both steady state and transient conditions. The identification and characterization of the relevant thermal hydraulic phenomena, and the assessment and validation of thermal hydraulic systems codes, has been the objective of multiple international research programs. The validation and…