0000000000748533
AUTHOR
A Huber
Abdominal wall reconstruction by a regionally distinct biocomposite of extracellular matrix digest and a biodegradable elastomer.
Current extracellular matrix (ECM) derived scaffolds offer promising regenerative responses in many settings, however in some applications there may be a desire for more robust and long lasting mechanical properties. A biohybrid composite material that offers both strength and bioactivity for optimal healing towards native tissue behavior may offer a solution to this problem. A regionally distinct biocomposite scaffold composed of a biodegradable elastomer (poly(ester urethane)urea) and porcine dermal ECM gel was generated to meet this need by a concurrent polymer electrospinning/ECM gel electrospraying technique where the electrosprayed component was varied temporally during the processing…
Etoposide Treatment in Recurrent Medulloblastoma
Five consecutive patients with recurrent medulloblastoma received etoposide 120 mg/m2 for 5 to 7 days at 2 to 4-week intervals. Three patients with neuroaxis dissemination received additional intrathecal chemotherapy with methotrexate, cytosine arabinoside and prednisone. Toxicity consisted of alopecia and mild neutropenia. Complete response was registered in two patients, partial response in one. Median survival was 19 months with the 3 responders living 6, 30 and 60+ months. Etoposide seems to be an active agent in medulloblastoma.
Isotope removal experiment in JET-ILW in view of T-removal after the 2nd DT campaign at JET
Abstract A sequence of fuel recovery methods was tested in JET, equipped with the ITER-like beryllium main chamber wall and tungsten divertor, to reduce the plasma deuterium concentration to less than 1% in preparation for operation with tritium. This was also a key activity with regard to refining the clean-up strategy to be implemented at the end of the 2nd DT campaign in JET (DTE2) and to assess the tools that are envisaged to mitigate the tritium inventory build-up in ITER. The sequence began with 4 days of main chamber baking at 320 °C, followed by a further 4 days in which Ion Cyclotron Wall Conditioning (ICWC) and Glow Discharge Conditioning (GDC) were applied with hydrogen fuelling,…
Precision electroweak measurements on the Z resonance
We report on the final electroweak measurements performed with data taken at the Z resonance by the experiments operating at the electron-positron colliders SLC and LEP. The data consist of 17 million Z decays accumulated by the ALEPH, DELPHI, L3 and OPAL experiments at LEP, and 600 thousand Z decays by the SLD experiment using a polarised beam at SLC. The measurements include cross-sections, forward-backward asymmetries and polarised asymmetries. The mass and width of the Z boson, $\MZ$ and $\GZ$, and its couplings to fermions, for example the $\rho$ parameter and the effective electroweak mixing angle, are precisely measured. The number of light neutrino species is determined to be 2.9840…