0000000000749695

AUTHOR

Andreas Rogalewski

0000-0002-6525-4832

showing 2 related works from this author

Semaphorin 6A Improves Functional Recovery in Conjunction with Motor Training after Cerebral Ischemia

2010

Stroke is a major health problem in industrialized societies. Despite numerous attempts at developing acute stroke therapies aimed at minimizing acute infarct development, the only approved therapy so far is recombinant tissue plasminogen activator (rtPA). In recent years, the attention of the stroke community has therefore also put increased emphasis on understanding processes of post-stroke recovery, and their potential exploitability for therapeutic purposes. The brain has a remarkable ability to adapt to changes after stroke. Mechanisms that contribute to this plasticity are re-mapping and expansion of cortical areas to neighboring regions of functional motor cortex areas after injury […

CerebellumPathologymedicine.medical_specialtyanimal structures610lcsh:MedicineSemaphorinsMotor ActivityBiologyBrain IschemiaCell LineNeuroscience/Motor SystemsSemaphorinPhysical Conditioning AnimalCortex (anatomy)NeuroplasticitymedicineAnimalsHumanslcsh:ScienceMultidisciplinarylcsh:RNeurogenesisNeurological Disorders/Cerebrovascular DiseaseRecovery of FunctionDependovirusRatsStrokemedicine.anatomical_structurenervous systemembryonic structuresCorticospinal tractlcsh:QAxon guidancesense organsNeuroscience/Neurobiology of Disease and RegenerationNeurosciencePsychomotor PerformanceResearch ArticleMotor cortexPLoS ONE
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Repetitive TMS temporarily alters brain diffusion

2004

The authors investigated whether repetitive transcranial magnetic stimulation (rTMS) at 1 Hz (12 minutes; 90% of motor threshold) to the primary motor cortex (M1) leads to changes in diffusion-weighted imaging (DWI). After the rTMS train, there was a temporary small restriction in diffusion within the targeted left M1 that disappeared after 5 minutes. These findings provide a physiologic correlate to the reported behavioral consequences of off-line 1-Hz rTMS and reveal the transitory nature of the effects.

Motor thresholdAdultMaleTime Factorsmedicine.medical_treatmentMotor Cortexdiffusion-weighted imaging repetitive transcranial magnetic stimulationMagnetic Resonance ImagingTranscranial magnetic stimulationDiffusionMagneticsmedicineHumansNeurology (clinical)Primary motor cortexDiffusion (business)PsychologyNeuroscience
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