0000000000762908

AUTHOR

Y. Hancock

showing 2 related works from this author

Pathogens and host immunity in the ancient human oral cavity.

2014

Calcified dental plaque (dental calculus) preserves for millennia and entraps biomolecules from all domains of life and viruses. We report the first high-resolution taxonomic and protein functional characterization of the ancient oral microbiome and demonstrate that the oral cavity has long served as a reservoir for bacteria implicated in both local and systemic disease. We characterize: (i) the ancient oral microbiome in a diseased state, (ii) 40 opportunistic pathogens, (iii) the first evidence of ancient human-associated putative antibiotic resistance genes, (iv) a genome reconstruction of the periodontal pathogen Tannerella forsythia, (v) 239 bacterial and 43 human proteins, allowing co…

ProteomeMolecular Sequence Data610 Medicine & health10071 Functional Genomics Center ZurichDental plaqueArticlePrehistòriaBacterial geneticsPeriodontal pathogenMicrobiology1311 GeneticsTandem Mass SpectrometryGermanyRNA Ribosomal 16SGeneticsmedicineTannerella forsythiaHumansDental CalculusMicrobiomePathogenPhylogenyMouthbiologyBase SequenceEcologyBacteroidetesMicrobiotaSequence Analysis DNAbiology.organism_classificationmedicine.diseaseRed complexHistory Medieval10182 Institute of Oral Biologystomatognathic diseasesArchaeology10076 Center for Integrative Human Physiology11294 Institute of Evolutionary Medicine570 Life sciences; biologyOral MicrobiomeFood AnalysisGenome BacterialNature genetics
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Shell sclerochronology and stable isotopes of the bivalve Anomalocardia flexuosa (Linnaeus, 1767) from southern Brazil: Implications for environmenta…

2017

Abstract This study presents the first stable isotopic and sclerochronological calibration of the bivalve Anomalocardia flexuosa (Linnaeus, 1767) in relation to environmental variables in a subtropical coastal area of southern Brazil. We investigate incremental shell growth patterns and δ18O and δ13C values of modern specimens collected alive from the Laguna Lagoonal System (LLS). Shells of Anomalocardia flexuosa are also one of the main biological components of pre-Columbian archaeological shell mounds and middens distributed along the Brazilian coastline. We therefore selected archaeological specimens from a local late Holocene shell mound (Cabecuda) to compare their stable carbon and oxy…

010506 paleontology010504 meteorology & atmospheric sciencesδ13Cδ18OStable isotope ratioPaleontologySubtropicsOceanography01 natural sciencesArchaeologyIsotopes of oxygenMiddenSclerochronologyISÓTOPOS ESTÁVEISEcology Evolution Behavior and SystematicsGeologyHolocene0105 earth and related environmental sciencesEarth-Surface ProcessesPalaeogeography, Palaeoclimatology, Palaeoecology
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