0000000000778968

AUTHOR

Stephen P. Fortmann

showing 4 related works from this author

A common biological basis of obesity and nicotine addiction

2013

Contains fulltext : 128630.pdf (Publisher’s version ) (Open Access) Smoking influences body weight such that smokers weigh less than non-smokers and smoking cessation often leads to weight increase. The relationship between body weight and smoking is partly explained by the effect of nicotine on appetite and metabolism. However, the brain reward system is involved in the control of the intake of both food and tobacco. We evaluated the effect of single-nucleotide polymorphisms (SNPs) affecting body mass index (BMI) on smoking behavior, and tested the 32 SNPs identified in a meta-analysis for association with two smoking phenotypes, smoking initiation (SI) and the number of cigarettes smoked …

obesityFOOD-INTAKETAG Consortiummedicine.medical_treatmentOxford-GSK ConsortiumLOCIIcelandAetiology screening and detection [ONCOL 5]VARIANTS3124 Neurology and psychiatryNicotine0302 clinical medicineDEPENDENCE030212 general & internal medicineAge of OnsetENGAGE consortiumPOPULATIONAddiction; Body Mass Index; Nicotine dependence; Smokingmedia_commonPsychiatry2. Zero hunger0303 health scienceseducation.field_of_studyASSOCIATIONTobacco Use DisorderDSM-VCANCER3142 Public health care science environmental and occupational health3. Good healthPsychiatry and Mental healthMeta-analysis/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingOriginal ArticleaddictionLife Sciences & Biomedicinemedicine.drugmedicine.medical_specialtymedia_common.quotation_subjectPopulationbody mass indexPolymorphism Single Nucleotidesmoking03 medical and health sciencesCellular and Molecular NeuroscienceSDG 3 - Good Health and Well-beingInternal medicinemedicineHumansSMOKING-BEHAVIORnicotine dependencePsychiatryeducationBiological PsychiatryMolecular epidemiology Aetiology screening and detection [NCEBP 1]030304 developmental biologyScience & Technologybusiness.industryAddictionAppetitemedicine.diseaseObesityBODY-MASS INDEXBehavior AddictiveEndocrinologySmoking cessationbusinessBody mass indexTranslational Psychiatry
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Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

2016

Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for estimated glomerular filtration rate (eGFR), combining data across 133,413 individuals with replication in up to 42,166 individuals. We identify 24 new and confirm 29 previously identified loci. Of these 53 loci, 19 associate with eGFR among individuals with diabetes. Using bioinformatics, we show that identified genes at eGFR loci are enriched for expression in kidney tissues and in pathways relevant for kidney development and transmembrane transporter activity, kidney structure, and regulation o…

0301 basic medicineNephrologyGenetics and Molecular Biology (all)estimated glomerular filtration rateestimated glomerular filtration rate chronic kidney disease genetic determinantsGeneral Physics and AstronomyKidney developmentGenome-wide association studyBiochemistrySettore MED/14 - NEFROLOGIARenal InsufficiencyChronicGeneticsAGEN Consortiumddc:616education.field_of_studyKidneyStage renal-diseaseMultidisciplinaryGenome-wide associationCHARGe-Heart Failure GroupGene Expression Regulation; Genome-Wide Association Study; Genotype; Humans; Renal Insufficiency Chronic; Genetic Predisposition to Disease; Biochemistry Genetics and Molecular Biology (all); Chemistry (all); Physics and Astronomy (all)QChemistry (all)MetaanalysisGene Expression Regulation; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Humans; Renal Insufficiency Chronic/geneticsBiological sciencesSerum creatininemedicine.anatomical_structureEfficientRonyons -- FisiologiaHypertensionICBP ConsortiumTransmembrane transporter activitygenetic association loci kidney functionCARDIOGRAMHumanmedicine.medical_specialtyGenotypeSciencePopulationRenal functionECHOGen ConsortiumReplicationBiologyEnvironmentResearch SupportGeneral Biochemistry Genetics and Molecular BiologyN.I.H.genetic determinants03 medical and health sciencesPhysics and Astronomy (all)GENOME-WIDE ASSOCIATION ; FALSE DISCOVERY RATES ; STAGE RENAL-DISEASE ; SERUM CREATININE ; METAANALYSIS ; VARIANTS ; INDIVIDUALS ; POPULATION ; RISK ; HYPERTENSIONKidney functionResearch Support N.I.H. ExtramuralInternal medicineMD MultidisciplinarymedicineGeneticsJournal ArticleHumanseGFRcrea; eGFRcysGenetic Predisposition to Diseaseddc:610GenetikRenal Insufficiency ChronicMortalityeducationddc:613Biochemistry Genetics and Molecular Biology (all)urogenital systemIndividualsExtramuralGeneral Chemistryta3121medicine.diseaseR1030104 developmental biologyGene Expression RegulationBiochemistry Genetics and Molecular Biology (all); Chemistry (all); Physics and Astronomy (all)570 Life sciences; biologyGenèticachronic kidney diseaseKidney diseaseGenome-Wide Association StudyMeta-Analysis
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A century of trends in adult human height

2016

Article

estatura corporalEpidemiologyComputingMilieux_LEGALASPECTSOFCOMPUTINGmedical research;pituuskasvuGlobal Healthmedical research0302 clinical medicineadultsPublic health surveillanceBiology (General)ComputingMilieux_MISCELLANEOUSheight ; global ; trendsPOPULATIONHuman Nutrition & Healthbiological sciences;education.field_of_studyEVOLUÇÃO HUMANAbiological sciencesHumane Voeding & GezondheidGeneral MedicineadultoHälsovetenskaperBiological sciencesnutritionOF-THE-LITERATUREMedicineGROWTHHEALTHPublic HealthHumanQH301-705.5ScienceSECULAR CHANGESSocio-culturaleGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesEpidemiology; Public HealthMedical researchNoneHealth SciencesHumansHuman heighteducationVLAGNeuroscience (all)Biochemistry Genetics and Molecular Biology (all)Adult human heightCHILD UNDERNUTRITION030104 developmental biologyBody mass index030217 neurology & neurosurgeryheightDemography0301 basic medicineSettore MED/09 - Medicina InternaNutrition and DiseaseImmunology and Microbiology (all)[SDV]Life Sciences [q-bio]humanosbiological sciences; epidemiology; global health; medical research; none; nutritionVoeding en ZiekteStature -- History -- 20th centuryMedicine and Health SciencesBiological sciencesaikuisetGeneral NeuroscienceQRPublic Health Global Health Social Medicine and EpidemiologyBody sizenone;biological sciences; epidemiology; global health; medical research; none; nutrition; Adult; Global Health; Humans; Body Height; Neuroscience (all); Biochemistry Genetics and Molecular Biology (all); Immunology and Microbiology (all)epidemiology;Adult height//purl.org/pe-repo/ocde/ford#3.01.03 [https]Research Articletrendsglobal health;AdultSTATURESouth asia//purl.org/pe-repo/ocde/ford#1.06.03 [https]Stature TallPopulationGlobal healthJournal ArticleLife ScienceGeneral Immunology and Microbiologybiological science//purl.org/pe-repo/ocde/ford#3.01.04 [https]Quarter (United States coin)Body HeighttrenditBODY-MASS INDEXFolkhälsovetenskap global hälsa socialmedicin och epidemiologikorkeusEpidemiology and Global HealthCancer incidenceCANCER INCIDENCEWEIGHT
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Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19.2 million …

2016

Copyright © NCD Risk Factor Collaboration. Open Access article distributed under the terms of CC BY.

MaleObesidadCHILDRENSaludReviewpaíses desarrolladosGlobal HealthBody Mass IndexBody mass index population study0302 clinical medicineModelsFactores de riesgo cardiovascularMedicinebody mass index ; underweight ; overweight ; obesityYoung adultHuman Nutrition & Healtheducation.field_of_studyHumane Voeding & GezondheidGeneral MedicineASSOCIATION11 Medical And Health Sciencesadultopredicciónadulto jovenCARDIOVASCULAR-DISEASEthinness/epidemiologyNONCOMMUNICABLE DISEASESNCD Risk Factor Collaboration (NCD-RisC)Enfermedades cardiovascularesDeveloped countryteorema de BayesMedical sciences03 medical and health sciencesSDG 3 - Good Health and Well-beingThinnessHumanseducationDeveloping CountriesobesidadVLAGScience & TechnologyModels StatisticalCAUSE-SPECIFIC MORTALITYBayes Theoremmedicine.diseaseQPObesityadult body-massIndice de masa corporal (IMC)RISK-FACTORSAdolescent; Adult; Bayes Theorem; Body Mass Index; Developed Countries; Developing Countries; Female; Forecasting; Global Health; Humans; Male; Models Statistical; Obesity/epidemiology; Prevalence; Thinness/epidemiology; Young AdultRABody mass indexDemographyMeta-AnalysisGerontologySettore MED/09 - Medicina InternaNutrition and DiseasehumanosadolescenteOverweightpaíses en desarrolloVoeding en ZiekteMedicine and Health SciencesGlobal healthPrevalence030212 general & internal medicineNon-U.S. Gov'tMedicine (all)Research Support Non-U.S. Gov'tprevalenciaPublic Health Global Health Social Medicine and EpidemiologyStatisticalAdolescent; Adult; Bayes Theorem; Developed Countries; Developing Countries; Female; Forecasting; Humans; Male; Models Statistical; Obesity; Prevalence; Thinness; Young Adult; Body Mass Index; Global Health; Medicine (all)/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleUnderweightmedicine.symptompooled analysisLife Sciences & Biomedicineobesity/*epidemiologyAdultAdolescentPopulation030209 endocrinology & metabolismResearch SupportYoung AdultMedicine General & InternalEPIDEMICGeneral & Internal MedicineJournal ArticleLife Scienceddc:610ObesityObesidad morbidaOBESITY PREVENTIONOVERWEIGHTbusiness.industryDeveloped Countriesíndice de masa corporalCOHORTS//purl.org/pe-repo/ocde/ford#3.02.00 [https]Folkhälsovetenskap global hälsa socialmedicin och epidemiologiCiencias socio biomédicasbusinessdelgadezForecasting
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