0000000000786177
AUTHOR
G. Brodesser
Binding of water and solvent molecules in a 25-membered-ring host compound
The macrocyclic 15- and 25-membered-ring pyridine oligomers 1 and 2 containing three and five methoxy substituents in the 4-position of the pyridine rings were prepared by Muller-Roscheisen cyclization and then isolated by chromatography. They are attractive as synthetic endobasic receptor molecules. X-ray structure analysis exhibits the inclusion of hydrogen-bonded solvent molecules (water and trichloromethane) inside the pentameric macrocycle 2.
Homocalixpyridines: Ligands Exhibiting High Selectivity in Extraction and Sensor Processes
A novel spherical host architecture, based on pyridine subunits, has been created. It exhibits selective complexing properties toward soft metal ions (right), which have been tested in extraction and sensor processes. The complex-forming behaviour can be tailored by variation of the size of the cavity and by substitution. Homocalixpyridines are interesting in view of their application as selective carriers in separation and sensing techniques.