6533b832fe1ef96bd129a2e6
RESEARCH PRODUCT
Binding of water and solvent molecules in a 25-membered-ring host compound
Fritz VögtleMartin NiegerKari RissanenG. Brodessersubject
Solventchemistry.chemical_compoundStructure analysisChemistryStereochemistryPolymer chemistryPyridineMoleculeGeneral ChemistryRing (chemistry)description
The macrocyclic 15- and 25-membered-ring pyridine oligomers 1 and 2 containing three and five methoxy substituents in the 4-position of the pyridine rings were prepared by Muller-Roscheisen cyclization and then isolated by chromatography. They are attractive as synthetic endobasic receptor molecules. X-ray structure analysis exhibits the inclusion of hydrogen-bonded solvent molecules (water and trichloromethane) inside the pentameric macrocycle 2.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1993-01-01 | Recueil des Travaux Chimiques des Pays-Bas |