0000000000787325

AUTHOR

Claire Beausoleil

showing 2 related works from this author

Regulatory and academic studies to derive reference values for human health: The case of bisphenol S

2022

We would like to thank the HBM4EU team including Petra Apel (UBA), Matthieu Meslin and Christophe Rousselle (Anses) for their scientific contribution, as well as the ANSES Working Group on endocrine disruption, and its scientific Anses coordinators François Pouzaud and Sandrine Charles.; International audience; The close structural analogy of bisphenol (BP) S with BPA, a recognized endocrine-disrupting chemical and a substance of very high concern in the European Union, highlights the need to assess the extent of similarities between the two compounds and carefully scrutinize BPS potential toxicity for human health. This analysis aimed to investigate human health toxicity data regarding BPS…

MaleSwineBisphenol SPhysiologyBiological Availability010501 environmental sciencesBiologyEndocrine Disruptors01 natural sciencesBiochemistry03 medical and health scienceschemistry.chemical_compoundHuman healthPhenolsReference ValuesMESH: Policy MakingPolicy makingmedia_common.cataloged_instanceAnimalsHumansSulfonesEuropean unionBenzhydryl Compounds030304 developmental biology0105 earth and related environmental sciencesGeneral Environmental Sciencemedia_common0303 health sciencesPotential impactToxicity3. Good healthBioavailabilityMESH: Endocrine Disruptors[SDV.TOX] Life Sciences [q-bio]/ToxicologyBisphenol SchemistryReference values[SDV.TOX]Life Sciences [q-bio]/ToxicologyToxicityHealth-based guidance valueFemaleEndocrine-disrupting chemicalTarget organhormones hormone substitutes and hormone antagonists
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Regulatory identification of BPA as an endocrine disruptor : Context and methodology

2018

International audience; BPA is one of the most investigated substances for its endocrine disruptor (ED) properties and it is at the same time in the center of many ED-related controversies, the analysis on how BPA fits to the regulatory identification as an ED is a challenge in terms of methodology. It is also a great opportunity to test the regulatory framework with a uniquely data-rich substance and learn valuable lessons for future cases. From this extensive database, it was considered important to engage in a detailed analysis so as to provide specific and strong evidences of ED while reflecting accurately the complexity of the response as well the multiplicity of adverse effects. An ap…

0301 basic medicineendocrine systemBrain developmentpertubateur endocrinienEndocrine disruptionContext (language use)Computational biologyMESH: Social Control Formal010501 environmental sciencesBiologyEndocrine Disruptors01 natural sciencesBiochemistryMammary gland developmentbisphenol A;endocrine disruption;ED;SVHC;substance of very high concern;REACh03 medical and health sciencesEndocrinologyBisphenol AMESH: PhenolsPhenolsSubstance of very high concernMESH: Benzhydryl CompoundsFood and Nutritionbisphénol aAnimalsHumansBenzhydryl CompoundsMolecular BiologyComputingMilieux_MISCELLANEOUSSVHC0105 earth and related environmental sciencesEndocrinology and metabolismurogenital systemsubstance toxiqueED3. Good healthSocial Control FormalMESH: Endocrine Disruptors030104 developmental biologyEndocrine disruptor[SDV.TOX]Life Sciences [q-bio]/ToxicologyAlimentation et NutritionEndocrinologie et métabolismeREACHIdentification (biology)
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