0000000000810944

AUTHOR

M. Leboyer

showing 3 related works from this author

Genetic and psychosocial stressors have independent effects on the level of subclinical psychosis: findings from the multinational EU-GEI study.

2022

the Spanish Ministry of Science and Innovation. Instituto de Salud Carlos III (SAM16PE07CP1, PI16/02012, PI19/024), co-financed by ERDF Funds from the European Commission, ‘A way of making Europe’, CIBERSAM. Madrid Regional Government (B2017/BMD-3740 AGES-CM-2), European Union Structural Funds. European Union Seventh Framework Program under grant agreements FP7-4-HEALTH-2009-2.2.1-2-241909 (Project EU-GEI) and FP7-HEALTH-2013-2.2.1-2-603196 (Project PSYSCAN); and European Union H2020 Program under the Innovative Medicines Initiative 2 Joint Undertaking (grant agreement No 115916, Project PRISM, and grant agreement No 777394, Project AIMS-2-TRIALS) (...)

Schizophrenia/geneticsEnvironmental effects on human beingsRisk factors in diseasesEpidemiologyPsicosipsychosiPathological psychologyGenes × environment interactionRisk FactorsSettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.psychosocial stressorsHumanspsychosisPsychotic Disorders/geneticsSettore MED/25 - PsichiatriaInfluència del medi ambient en l'homeGenètica de la conductaFactors de risc en les malaltiesGenes × environment interactionsPublic Health Environmental and Occupational HealthPsychosespolygenic risk score for schizophreniaPsicopatologiaPsychiatry and Mental healthPsychotic DisordersBehavior geneticsSchizophreniaEsquizofrèniaGene-Environment Interaction
researchProduct

Childhood Trauma increases suicidal behaviour in a treatment-resistant depression population: a FACE-DR report

2021

International audience; Objective: In addition to heredity, exposure to early-life adversity is an important predisposing risk factor of suicidal behaviour. Although the association between Childhood Trauma (CT) and suicide risk is well documented, interactions between CT and suicidal behaviour in Treatment-Resistant Depression (TRD) populations have received little coverage. This study aimed to evaluate i) association between CT and suicidal behaviour in a TRD population, and ii) the role of personality traits and impulsiveness as potential factors of mediation in these associations.Methods: Patients were recruited from a cohort of the French network of TRD expert centers. Depressive sympt…

Depressive disordersMESH: DepressionMESH: ViolencePopulationPoison controlViolenceSuicide preventionChildhood traumaMESH: Depressive Disorder Treatment-ResistantSuicidal IdeationDepressive Disorder Treatment-Resistant03 medical and health sciences0302 clinical medicineMESH: Risk FactorsRisk FactorsRating scaleSurveys and QuestionnairesHumansMedicineMESH: Surveys and QuestionnairesRisk factoreducationSuicidal ideationChildhood neglectBiological Psychiatryeducation.field_of_studyMESH: HumansMESH: Suicidal IdeationDepressionbusiness.industryChildhood abuseCTQ tree3. Good health030227 psychiatrySuicidePsychiatry and Mental health[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental healthTreatment-resistant depressionmedicine.symptomColumbia Suicide Severity Rating Scalebusiness030217 neurology & neurosurgeryClinical psychology
researchProduct

Premorbid Adjustment and IQ in Patients With First-Episode Psychosis: A Multisite Case-Control Study of Their Relationship With Cannabis Use

2020

Abstract Psychotic patients with a lifetime history of cannabis use generally show better cognitive functioning than other psychotic patients. Some authors suggest that cannabis-using patients may have been less cognitively impaired and less socially withdrawn in their premorbid life. Using a dataset comprising 948 patients with first-episode psychosis (FEP) and 1313 population controls across 6 countries, we examined the extent to which IQ and both early academic (Academic Factor [AF]) and social adjustment (Social Factor [SF]) are related to the lifetime frequency of cannabis use in both patients and controls. We expected a higher IQ and a better premorbid social adjustment in psychotic p…

MalecognitionIntelligenceComorbiditySUBSTANCE USE DISORDERS0302 clinical medicineSettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.MedicinePREDICTORSRISKeducationeducation.field_of_studybiologyCognitionMiddle AgedPsychosocial FunctioningsociabilityPsychiatry and Mental healthSchizophreniaFemaleMarijuana UseSocial AdjustmentMENTAL-HEALTHAdultmedicine.medical_specialtyPsychosisAdolescentPopulation1ST EPISODEDRUG-USEpreillnessSettore MED/01 - Statistica MedicaYoung Adult03 medical and health sciencesAGESettore M-PSI/08 - Psicologia ClinicaHumansCognitive skilleducationPsychiatrySettore MED/25 - Psichiatriabusiness.industryCase-control studypreillnebiology.organism_classificationmedicine.diseaseEDUCAÇÃO030227 psychiatryschizophreniaPsychotic DisordersCase-Control StudiesONSETCannabisNEUROCOGNITIONbusinessmarijuanaNeurocognitive030217 neurology & neurosurgeryRegular ArticlesSchizophrenia Bulletin
researchProduct