Corrigendum to “Premature ovarian senescence and a high miscarriage rate impair fertility in women with HCV” [J Hepatol 68 (2018) 33–41](S0168827817322596)(10.1016/j.jhep.2017.08.019)

It has come to our attention that the PITER framework investigator, Alessandro Federico, was incorrectly listed as F. Alessandro in the original manuscript. Please note that the correct name of this author is Alessandro Federico (2nd University of Naples). The correct list of PITER investigators is in the footnote below.

UNA RARA INDICAZIONE ALLA LOBECTOMIA DEL NEONATO: L'Emangioendotelioma complicato

L'Emangioendotelioma epatico (EEE) è un raro tumore benigno vascolare dell'età pediatrica di maggiore riscontro nella prima infanzia, periodo durante il quale può essere causa di notevoile morbilità e mortalità per le temibili complicanze possibili. Gli Autori presentano un caso di EEE nel neonato, occorso alla loro osservazione e discutono le problematiche relative alla diagnosi ed al trattamento

YOLK SAC deL TESTICOLO. Raro caso con metastasi retroperitoneale

Gli Autori riportano un caso di tumore primitivo del testicolo (Yolk Sac Tumor) e metastasi gigante retroperitoneale e sindrome virilizzante associata

Ultrasonography and gastric emptying: evaluation in infants with gastroesophageal reflux.

We have applied ultrasonography to the evaluation of gastric emptying in children. Two different populations have been investigated: normal children and children with gastroesophageal reflux. All the patients were less than 6 months of age. The diagnosis of gastroesophageal reflux was defined by 24-h pH measurement. The technique, used to measure gastric emptying, is the one described by Bolondi et al. In this research we used the simplified method. All children had been submitted to the examination after 4-h fasting. The standard meal was the usual milk formula, 300 ml/m2 body surface area (BSA). A cross-section area of the gastric antrum was determined before a meal and every 15 min for 2…

Feasibility and physics potential of detecting $^8$B solar neutrinos at JUNO

The Jiangmen Underground Neutrino Observatory (JUNO) features a 20 kt multi-purpose underground liquid scintillator sphere as its main detector. Some of JUNO's features make it an excellent location for 8B solar neutrino measurements, such as its low-energy threshold, high energy resolution compared with water Cherenkov detectors, and much larger target mass compared with previous liquid scintillator detectors. In this paper, we present a comprehensive assessment of JUNO's potential for detecting 8B solar neutrinos via the neutrino-electron elastic scattering process. A reduced 2 MeV threshold for the recoil electron energy is found to be achievable, assuming that the intrinsic radioactive …

LA SINDROME DI PRUNE-BELLY: Considerazioni cliniche e terapeutiche

La Sindrome di Prune-Belly si può manifestare con una ampia varietà di quadri clinici,a prognosi variabile anche in rapporto al grado di compromissione renale. Gli Autori presentano uno studio retrospettivo su 6 casi osservati dal 1980 al 1991 e discutono l'importanza di un corretto inquadramento diagnostico e terapeutico

The first coronal mass ejection observed in both visible-light and UV HI Ly-α channels of the Metis coronagraph on board Solar Orbiter

Context.The Metis coronagraph on board Solar Orbiter offers a new view of coronal mass ejections (CMEs), observing them for the first time with simultaneous images acquired with a broad-band filter in the visible-light interval and with a narrow-band filter around the H ILy-αline at 121.567 nm, the so-called Metis UV channel.Aims.We show the first Metis observations of a CME, obtained on 16 and 17 January 2021. The event was also observed by the EUI/FSI imager on board Solar Orbiter, as well as by other space-based coronagraphs, such as STEREO-A/COR2 and SOHO/LASCO/C2, whose images are combined here with Metis data.Methods.Different images are analysed here to reconstruct the 3D orientation…

Premature ovarian senescence and a high miscarriage rate impair fertility in women with HCV

Background & Aims Premenopausal women who are HCV positive (HCV+) have failing ovarian function, which is likely to impact their fertility. Thus, we investigated the reproductive history, risk of infertility, and pregnancy outcomes in women of childbearing age who were HCV+. Methods Three different groups were studied: (1) Clinical cohort: 100 women who were HCV+ and also had chronic liver disease (CLD), age matched with 50 women who were HBV+ with CLD and with 100 healthy women; all women were consecutively observed in three gastroenterology units in hospitals in Italy; (2) 1,998 women who were HCV+ and enrolled in the Italian Platform for the Study of Viral Hepatitis Therapies (PITER)…

IL TERATOMA CERVICALE

The Authors present a case of Cervical Teratoma in newborn and analyze the optimal diagnostic and therapeutic approach.

IL TUMORE DI ASKIN. Descrizione di un caso clinico e Revisione della Letteratura

The Authors report a case of Askin's tumor, considered a peripheral Neuroectodermal tumor (PNET) and the correct treatment on diagnosi and therapy is reported

TERATOMI SACRO-COCCIGEI: Osservazioni su 25 casi

Gli Autori presentano i dati relativi ad uno studio retrospettivo su 25 casi di Teratoma sacrococcigeo, osservati tra il 1980 ed il 1988.

YOLK SAC DEL TESTICOLO: Raro Caso con Metastasi Gigante Retroperitoneale

The authors restorate a case of primary testis tumor (Yolk Sac Tumor) and giant retroperitoneal metastasis clinically evident as a voluminous abdominal mass (23 cm) and associated virilizing syndrome. the diagnostic and therapeutic procedure performed is described.

IL TERATOMA ED IL CHIRURGO PEDIATRA. Considerazioni sull'approccio e valutazioni dalla Casistica Nazionale "TCG 91".

Germ Cell Tumors (GCT) are rare in childhood, accounting for 2-4% of all solid neoplasms. Teratoma is the most frequent histological type (50%) of GCT and the most important neonatal tumors.. Authors analyze the results of the first Italian Multicentric Cooperative Study on GCTs in childhood (TCG 91). The role of surgical radical excision of the mass with thw coccyx in sacrococcygeal forms is streassed.

Ewing sarcoma family of tumors: Causes, diagnosis and treatment

The Ewing's sarcoma Family of Tumors (EFT) includes classic Ewing's Sarcoma (ES) of bone, Extraskeletal Ewing's Sarcoma (EES) and malignant peripheral primitive Neuroectodermal Tumor (pNET) of bone and soft tissue. ES is an aggressive tumor with a high incidence of local recurrence and distant metastasis. The skeletal form is more common and typically occurs in the long bones of the extremities. The extra skeletal form occurs in the soft tissues of the lower extremities, paravertebral tissues, chest wall, retroperitoneum and rarely in the head and neck region in about 1-4% of cases. Involvement of the head and neck is usually identified in the nasal or oral cavities, sinuses or soft tissues…

LA DIAGNOSTICA DELLE TUMEFAZIONI PELVICHE NELL'INFANZIE e NELL'ADOLESCENZA

Le tumefazioni pelviche nell'infanzie e nell'adolescenza presentano una eterogeneità etioloogica. Gli autori analizzano gli aspetti diagnostici per imaging.

La cooperazione internazionale allo sviluppo. Costruire sull’esperienza. Presentazione

La propensione per lo studio delle specificità culturali ha fatto dell’antropologia una delle discipline direttamente interessate ai processi di mutamento pianificato. L’attenzione per la cooperazione internazionale allo sviluppo e alle sue ricadute professionali è stata ben presente nell’antropologia italiana e all’interno dei convegni SIAA, ma il dibattito in seno all’associazione è rimasto per il momento sottodimensionato rispetto a un altro ambito di grande interesse pubblico, la migrazione dai paesi affetti da conflitti e povertà verso l’Europa e al ruolo che gli antropologi possono svolgere nelle politiche di accoglienza.

Prioritization of high-cost new drugs for HCV: making sustainability ethical

Hepatitis C virus (HCV) infection is a major health problem worldwide. Chronic HCV infection may in the long run cause cirrhosis, hepatic decompensation and hepatocellular carcinoma, with an ultimate disease burden of at least 350,000 deaths per year worldwide. The new generation of highly effective direct acting antivirals (DAA) to treat HCV infection brings major promises to infected patients in terms of exceedingly high rates of sustained virological response (SVR) but also of tolerability, allowing even the sickest patients to be treated. Even in the face of the excellent safety and efficacy and wide theoretical applicability of these regimens, their introduction is currently facing cos…

Diagnosis and treatment of Ewing's Sarcoma of the tongue

The Ewing's sarcoma Family of Tumors (EFT) includes classic Ewing's Sarcoma (ES) of bone, Extraskeletal Ewing's Sarcoma (EES) and malignant peripheral primitive Neuroectodermal Tumor (pNET) of bone and soft tissue. ES is an aggressive tumor with a high incidence of local recurrence and distant metastasis. The skeletal form is more common and typically occurs in the long bones of the extremities. The extra skeletal form occurs in the soft tissues of the lower extremities, paravertebral tissues, chest wall, retroperitoneum and rarely in the head and neck region in about 1- 4% of cases. Involvement of the head and neck is usually identified in the nasal or oral cavities, sinuses or soft tissue…

Abstracts of scientific papers second international symposium on central nervous system monitoring

Economic Consequences of Investing in Anti-HCV Antiviral Treatment from the Italian NHS Perspective: A Real-World-Based Analysis of PITER Data

OBJECTIVE:\ud We estimated the cost consequence of Italian National Health System (NHS) investment in direct-acting antiviral (DAA) therapy according to hepatitis C virus (HCV) treatment access policies in Italy.\ud \ud METHODS:\ud A multistate, 20-year time horizon Markov model of HCV liver disease progression was developed. Fibrosis stage, age and genotype distributions were derived from the Italian Platform for the Study of Viral Hepatitis Therapies (PITER) cohort. The treatment efficacy, disease progression probabilities and direct costs in each health state were obtained from the literature. The break-even point in time (BPT) was defined as the period of time required for the cumulativ…