0000000000855836

AUTHOR

Antonio Losada

showing 8 related works from this author

Usefulness of a Comprehensive Cardiovascular Magnetic Resonance Imaging Assessment for Predicting Recovery of Left Ventricular Wall Motion in the Set…

2005

ObjectivesWe sought to evaluate the usefulness of a comprehensive assessment of four cardiovascular magnetic resonance imaging (CMR)-derived myocardial viability indexes in the setting of myocardial stunning.BackgroundCardiovascular magnetic resonance imaging allows the simultaneous assessment of several viability indexes.MethodsWe studied 40 patients with a first ST-segment elevation myocardial infarction (MI) and an open infarct-related artery. At the first week, using CMR, wall motion (WM), and four viability indexes were determined: wall thickness, WM improvement with low-dose dobutamine, perfusion, and transmural extent of necrosis. We created a comprehensive score based on the presenc…

MaleVentricular Function LeftPredictive Value of TestsmedicineHumansMyocardial infarctionMyocardial StunningMyocardial stunningmedicine.diagnostic_testbusiness.industryMagnetic resonance imagingRecovery of FunctionMiddle Agedmedicine.diseaseMagnetic Resonance Imagingmedicine.anatomical_structurePredictive value of testsFemaleDobutamineCardiology and Cardiovascular MedicineNuclear medicinebusinessPerfusionTIMIArterymedicine.drugJournal of the American College of Cardiology
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Limitaciones del blush miocárdico para el análisis de la perfusión miocárdica en pacientes con infarto agudo de miocardio y flujo TIMI 3

2006

Introduccion y objetivos Analizamos la variabilidad en la medicion del indice angiografico de blush entre un hospital universitario y un laboratorio central independiente, asi como su correlacion con la perfusion analizada mediante ecocardiografia miocardica con contraste intracoronario (EMC) y con la funcion ventricular a los 6 meses Metodos Se incluyo en el estudio a 40 pacientes con un primer infarto agudo de miocardio con elevacion del segmento ST, enfermedad de un vaso y arteria relacionada con el infarto abierta. La perfusion se cuantifico por angiografia (mediana quinto dia, rango de 3-7) mediante el blush miocardico en nuestro laboratorio y en un laboratorio central independiente. S…

business.industryMedicineCardiology and Cardiovascular MedicinebusinessHumanitiesRevista Española de Cardiología
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[Myocardial echocardiography with intracoronary injection of contrast in post-infarction patients. Implications and comparison with angiography and m…

2004

We analyzed the safety and feasibility of myocardial echocardiography with intracoronary injection of contrast, its effect on left ventricular remodeling and systolic function, and its relationship with angiography and magnetic resonance imaging (MRI) for the evaluation of post-infarction coronary microcirculation.Thirty patients with a first ST-elevation myocardial infarction and a patent infarct-related artery were studied. Mean perfusion score of the infarcted area was analyzed with myocardial echocardiography. TIMI and Blush grades (angiography) were determined. Mean perfusion score (MRI-perfusion), end-diastolic volume index and ejection fraction were determined with MRI. At 6 months a…

Malemedicine.medical_specialtyMyocardial InfarctionInfarctionCollateral CirculationContrast MediaPerfusion scanningCoronary AngiographyInternal medicineCoronary CirculationmedicineHumanscardiovascular diseasesMyocardial infarctionVentricular remodelingEjection fractionmedicine.diagnostic_testbusiness.industryMicrocirculationMyocardiumGeneral MedicineMiddle Agedmedicine.diseaseMagnetic Resonance ImagingMicrospheresLogistic ModelsEchocardiographyAngiographyMultivariate AnalysisCardiologyFemalebusinessNuclear medicinePerfusionTIMIRevista espanola de cardiologia
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Estudio de la perfusión coronaria postinfarto mediante análisis cuantitativo de la ecocardiografía miocárdica con inyección de contraste por vía intr…

2005

Introduccion y objetivos. Tras un infarto de miocardio el dano en la microcirculacion indica un peor pronostico. Investigamos la utilidad del estudio cuantitativo de la ecografia miocardica con inyeccion de contraste por via intravenosa (EMC-i.v.) para analizar la perfusion coronaria en comparacion con la inyeccion intracoronaria (EMC-i.c.). Pacientes y metodo. Estudiamos a 42 pacientes con un primer infarto con elevacion del segmento ST, enfermedad de un vaso y arteria abierta (TIMI 3, estenosis 0,75) y EMC-i.v. (perfusion de SonoVue, imagenes unicas capturando 1 de cada 6 ciclos con trigger en telesistole, perfusion normal si > 0,9). Se considero que un paciente tenia perfusion alterada s…

business.industryMedicineCardiology and Cardiovascular MedicineNuclear medicinebusinessRevista Española de Cardiología
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Study of Post-Infarction Coronary Perfusion Using Quantitative Analysis of Myocardial Echocardiography With Intravenous Injection of Contrast

2005

Introduction and objectives. After a myocardial infarction, damage to the microcirculation indicates a worse prognosis. We compared the usefulness of the quantitative analysis of myocardial contrast echocardiography with intravenous injection of contrast (MCE-iv) with intracoronary injection (MCE-ic) for analyzing coronary perfusion. Patients and method. We studied 42 patients with a first ST-elevation myocardial infarction, single-vessel disease and a patent artery (TIMI 3, stenosis 0.75) and MCE-iv (perfusion of SonoVue, singleimage capture in 1 out of each 6 cycles with trigger set at end-systole, perfusion considered normal if >0.9). Perfusion was considered abnormal if 2 or more segmen…

medicine.medical_specialtybusiness.industryPerfusion scanningGeneral Medicinemedicine.diseaseMicrocirculationStenosisText miningmedicine.anatomical_structureInternal medicinemedicineCardiologyMyocardial infarctionbusinessPerfusionTIMIArteryRevista Española de Cardiología (English Edition)
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Estudio de perfusión en pacientes postinfarto mediante ecografía miocárdica con inyección de contraste intracoronario. Implicaciones y relación con l…

2004

38 Objetivos. Analizamos la aplicabilidad y seguridad de la ecografia miocardica con inyeccion intracoronaria de contraste, su papel en la remodelacion ventricular y en la funcion sistolica, asi como su relacion con la angiografia y la resonancia magnetica para valorar la microcirculacion coronaria postinfarto. Pacientes y metodo. Se estudio a 30 pacientes con un primer infarto de miocardio con elevacion del segmento ST y arteria responsable abierta. Con inyeccion intracoronaria de contraste se determino la puntuacion media de perfusion en la zona infartada. Mediante angiografia se cuantificaron los grados TIMI y Blush. Se utilizo la resonancia magnetica para determinar la puntuacion media …

business.industryMedicineCardiology and Cardiovascular MedicinebusinessNuclear medicineRevista Española de Cardiología
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Limitations of Myocardial Blush Grade in the Evaluation of Myocardial Perfusion in Patients With Acute Myocardial Infarction and TIMI Grade 3 Flow

2006

Introduction and objectives An analysis was made of variability in the measurement of the angiographic index blush between a university hospital and an independent core laboratory, as well as its correlation with perfusion analised by intracoronary myocardial contrast echocardigraphy (MCE) and the ventricular function at the sixth month. Methods The study comprised 40 patients with a first ST-segment elevation myocardial infarction, single-vessel disease and open infarct-related artery. Perfusion was quantified by angiography (median fifth day, range 3-7) with blush in our laboratory and in an independent core laboratory. MCE was performed. Ejection fraction at the sixth month was determine…

MaleCardiac Catheterizationmedicine.medical_specialtyMyocardial InfarctionInfarctionMyocardial ReperfusionCoronary AngiographyElectrocardiographyCoronary CirculationInternal medicinemedicineHumansThrombolytic TherapyMyocardial infarctionAgedEjection fractionmedicine.diagnostic_testbusiness.industryStroke VolumeMagnetic resonance imagingGeneral MedicineMiddle Agedmedicine.diseaseMagnetic Resonance Imagingmedicine.anatomical_structureEchocardiographyAngiographyCardiologyFemalebusinessNuclear medicinePerfusionTIMIArteryRevista Española de Cardiología (English Edition)
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A non-valvular infective endocarditis in an HIV patient with myocardiopathy

2006

A 37-year-old woman presented in the emergency department revealing a history of HIV infection and C virus hepatitis diagnosed 15 years ago, acquired after a period of intravenous drug abusing. The patient was receiving triple antiHIV therapy and was in an A1 stage (last lymphocite recount of CD4: 0.63 10/l and no AIDS disease manifestation to the present moment). She described episodes, starting 20 days before, of torathic pain coexisting with shivers. There were no symptoms or signs of any focal infection. In the physical examination the only findings were a temperature of 38.4 8C, a 4 cm hepatomegaly and lipodystrophy. We found in the electrocardiogram a sinus rhythm, 96 bpm and no ST se…

HepatitisPediatricsmedicine.medical_specialtymedicine.diagnostic_testbusiness.industryPhysical examinationmedicine.diseaseFocal infection theoryAcquired immunodeficiency syndrome (AIDS)Infective endocarditismedicineEndocarditisBlood cultureSinus rhythmCardiology and Cardiovascular MedicinebusinessInternational Journal of Cardiology
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