Author: Susanne Endreβ

0000000000862975

AUTHOR

Susanne Endreβ

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Structure and Synthesis of a New Indole Alkaloid, 19 (S)-Hydroxy-Nb-methylraumacline, Obtained by the Biotransformation of Ajmaline in Plant Cell Cul…

1992

Abstract From the plant cell suspension cultures of Tauwolfia serpentina Benth ., which were cultivated in the alkaloid-production medium after feeding of ajmaline (1) , a new indole alkaloid 19- ( S )-hydroxy- N b -methylraumacline ( 4 ) was isolated. The structure of 4 first elucidated by spectroscopic analysis was determined by the chemical synthesis from ajmaline ( 1 ).

Indole alkaloidbiologyStereochemistryAlkaloidVerbenaceaeOrganic Chemistrybiology.organism_classificationBiochemistryChemical synthesisAjmalinechemistry.chemical_compoundBiotransformationBiosynthesischemistryCell cultureDrug Discoverymedicinemedicine.drugTetrahedron

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