0000000000867085

AUTHOR

Roya Khazaeli

showing 3 related works from this author

Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent

2019

Cattle were domesticated ∼10,000 years ago, but analysis of modern breeds has not elucidated their origins. Verdugo et al. performed genome-wide analysis of 67 ancient Near Eastern Bos taurus DNA samples. Several populations of ancient aurochs were progenitors of domestic cows. These genetic lineages mixed ∼4000 years ago in a region around the Indus Valley. Interestingly, mitochondrial analysis indicated that genetic material likely derived from arid-adapted Bos indicus (zebu) bulls was introduced by introgression.Science, this issue p. 173Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in mode…

0301 basic medicine010506 paleontologyMitochondrial DNA[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory1103Human Migration12041105IntrogressionZoologyGenomics01 natural sciencesDNA Mitochondrial[SHS]Humanities and Social SciencesDomesticationEvolution Molecular03 medical and health sciencesBronze AgeAnimals[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]Domestication0105 earth and related environmental sciences[SDV.EE]Life Sciences [q-bio]/Ecology environment[SDV.GEN]Life Sciences [q-bio]/GeneticsMultidisciplinaryGenomebiologyHuman migrationbusiness.industryGenomicsAurochsZebubiology.organism_classificationhumanities030104 developmental biologyFertilityCattlebusiness
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Tracking Five Millennia of Horse Management with Extensive Ancient Genome Time Series

2019

Summary Horse domestication revolutionized warfare and accelerated travel, trade, and the geographic expansion of languages. Here, we present the largest DNA time series for a non-human organism to date, including genome-scale data from 149 ancient animals and 129 ancient genomes (≥1-fold coverage), 87 of which are new. This extensive dataset allows us to assess the modern legacy of past equestrian civilizations. We find that two extinct horse lineages existed during early domestication, one at the far western (Iberia) and the other at the far eastern range (Siberia) of Eurasia. None of these contributed significantly to modern diversity. We show that the influence of Persian-related horse …

MaleRange (biology)BiologíaBreeding horsesBreedingGenomeDomestication0302 clinical medicinePaleobiologíaComputingMilieux_MISCELLANEOUSHistory AncientPhylogenyhorses0303 health sciencesDiversityGenomeAncient DNAanimal breedingBiological EvolutionmuleshumanitiesManagementEuropeDomestication animalEquestrian civilizationsEthnologyFemalemanagementequestrian civilizationsExtinct lineagesAsia[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and PrehistoryselectionMultiple allelesCaballosBiologyMulesArticleGeneral Biochemistry Genetics and Molecular Biologydiversity03 medical and health sciencesdomesticationCaballo de Przewalskiddc:570[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]AnimalsGenetic variationHorsesDNA AncientDomesticationSelectionancient DNAInstitut für Biochemie und Biologie030304 developmental biologyAnimal breedingSeries (stratigraphy)Genetic diversityGenetic VariationEquidaeGenéticaextinct lineagesAncient DNAdomestication ; selection ; equestrian civilizations ; horses ; ancient DNA ; mules ; animal breeding ; extinct lineages ; management ; diversityAnálisisancient DNA ; domestication ; animal breeding ; horses ; mules ; extinct lineages ; selection ; diversity ; management ; equestrian civilizations030217 neurology & neurosurgery
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Ancient goat genomes reveal mosaic domestication in the Fertile Crescent

2018

How humans got their goatsLittle is known regarding the location and mode of the early domestication of animals such as goats for husbandry. To investigate the history of the goat, Dalyet al.sequenced mitochondrial and nuclear sequences from ancient specimens ranging from hundreds to thousands of years in age. Multiple wild populations contributed to the origin of modern goats during the Neolithic. Over time, one mitochondrial type spread and became dominant worldwide. However, at the whole-genome level, modern goat populations are a mix of goats from different sources and provide evidence for a multilocus process of domestication in the Near East. Furthermore, the patterns described suppor…

0301 basic medicineFollistatinMESH: DomesticationAGRICULTURE1103CATTLEMESH: FollistatinMESH: AfricaGenome[SHS]Humanities and Social SciencesDomestication0601 history and archaeologyMESH: AnimalsMESH: Genetic VariationMESH: PhylogenyPhylogenyZAGROSmedia_common2. Zero hunger[SDV.EE]Life Sciences [q-bio]/Ecology environmentGenome1311MultidisciplinaryMiddle East060102 archaeologyMosaicismMESH: AsiaGoats06 humanities and the artsEuropeAnimals DomesticMESH: MosaicismReproductionTRAITSAsia[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistorymedia_common.quotation_subject1204BiologyDNA MitochondrialMESH: GoatsMosaic03 medical and health sciencesPhylogeneticsGenetic variationAnimalsMESH: GenomeMESH: Animals DomesticDNA AncientDietary change[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]Domestication[SDV.GEN]Life Sciences [q-bio]/GeneticsNEAR-EASTMESH: DNA MitochondrialGenetic VariationMESH: DNA AncientGENEMODEL030104 developmental biologySHEEPEvolutionary biologyORIGINSAfricaMESH: EuropeScience
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