6533b85bfe1ef96bd12baa89
RESEARCH PRODUCT
Tracking Five Millennia of Horse Management with Extensive Ancient Genome Time Series
Raquel Matoso SilvaEric BarreyMarjan MashkourMarjan MashkourEske WillerslevCarlos Fernández-rodríguezKhaled A. S. Al-rasheidMaria Do Mar OomPavel KuznetsovPavel A. KosintsevEloísa Bernáldez-sánchezSonia ShidrangMichael HofreiterKonstantin PitskhelauriSilvia Valenzuela-lamasSabine FelkelAli A. VahdatiCristina LuísCristina LuísEmma UsmanovaSainbileg UndrakhboldJón Hallsteinn HallssonJamsranjav BayarsaikhanVictor ZaibertIrina ShevninaSilvia AlbizuriHaeedeh LalehAnna DohrAhmed H. AlfarhanSanne BoessenkoolMorten E. AllentoftHoma FathiCleia DetryPetra Rajic SikanjicOleg MonchalovHeidi NistelbergerAlireza SardariJennifer A. LeonardJaco WeinstockChristian Mccrory ConstantzChristian Mccrory ConstantzAndaine Seguin-orlandoAndaine Seguin-orlandoJohanna LhuillierWolf-rüdiger TeegenNaveed KhanNaveed KhanSébastien LepetzLinas DaugnoraBazartseren BoldgivHelmut HemmerPeter Barros De DamgaardLembi LõugasVictor MerzLukas F. K. KudernaVedat OnarAngela SchlumbaumBarbara WallnerEsteban García-viñasEnkhbayar MijiddorjNadine DillFereidoun BiglariEric CrubézyBastiaan StarAlbína Hulda PálsdóttirAlbína Hulda PálsdóttirJosé D. GranadoTabaldiev KubatbekJohn SouthonAlan K. OutramCorina Liesau Von Lettow-vorbeckAnita Rapan PapešaNorbert BeneckeAmelie ScheuSimon TrixlAgnar HelgasonDorcas BrownHossein DavoudiCristina GambaJörg SchiblerRenate SchafbergJames H. BarrettDashzeveg TumenLudovic OrlandoLudovic OrlandoNurbol BaimukhanovAna Margarida ArrudaWilliam Timothy Treal TaylorFatemeh Azadeh MohasebFatemeh Azadeh MohasebMutalib KhasanovSabine Deschler-erbKari StefanssonCharleen GaunitzMélanie PruvostArturo MoralesRoya KhazaeliTomas Marques-bonetDavid W. AnthonyAitor Serres-armeroBenoît ClavelKamal TaheriKristian HanghøjKristian HanghøjBeth ShapiroArne LudwigArne LudwigSaleh A. AlquraishiAndrey LogvinGottfried BremKristian KristiansenNatalia RoslyakovaShiva Sheikhi SenoShiva Sheikhi SenoNaomi SykesNaomi SykesMaría Los ÁNgeles Chorro Y De De De Villa-ceballosJoachim BurgerEberhard SauerCatarina ViegasMietje GermonpréMichela LeonardiMichela LeonardiAntoine FagesAntoine FagesNathalie SerrandDiimaajav ErdenebaatarAleksei KasparovTajana Trbojević VukičevićVladimir V. PitulkoBryan K. MillerPablo LibradoPablo LibradoSturla EllingvågAriadna Nieto-espinetLuis Berrocal-rangelsubject
MaleRange (biology)BiologíaBreeding horsesBreedingGenomeDomestication0302 clinical medicinePaleobiologíaComputingMilieux_MISCELLANEOUSHistory AncientPhylogenyhorses0303 health sciencesDiversityGenomeAncient DNAanimal breedingBiological EvolutionmuleshumanitiesManagementEuropeDomestication animalEquestrian civilizationsEthnologyFemalemanagementequestrian civilizationsExtinct lineagesAsia[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and PrehistoryselectionMultiple allelesCaballosBiologyMulesArticleGeneral Biochemistry Genetics and Molecular Biologydiversity03 medical and health sciencesdomesticationCaballo de Przewalskiddc:570[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]AnimalsGenetic variationHorsesDNA AncientDomesticationSelectionancient DNAInstitut für Biochemie und Biologie030304 developmental biologyAnimal breedingSeries (stratigraphy)Genetic diversityGenetic VariationEquidaeGenéticaextinct lineagesAncient DNAdomestication ; selection ; equestrian civilizations ; horses ; ancient DNA ; mules ; animal breeding ; extinct lineages ; management ; diversityAnálisisancient DNA ; domestication ; animal breeding ; horses ; mules ; extinct lineages ; selection ; diversity ; management ; equestrian civilizations030217 neurology & neurosurgerydescription
Summary Horse domestication revolutionized warfare and accelerated travel, trade, and the geographic expansion of languages. Here, we present the largest DNA time series for a non-human organism to date, including genome-scale data from 149 ancient animals and 129 ancient genomes (≥1-fold coverage), 87 of which are new. This extensive dataset allows us to assess the modern legacy of past equestrian civilizations. We find that two extinct horse lineages existed during early domestication, one at the far western (Iberia) and the other at the far eastern range (Siberia) of Eurasia. None of these contributed significantly to modern diversity. We show that the influence of Persian-related horse lineages increased following the Islamic conquests in Europe and Asia. Multiple alleles associated with elite-racing, including at the MSTN “speed gene,” only rose in popularity within the last millennium. Finally, the development of modern breeding impacted genetic diversity more dramatically than the previous millennia of human management.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-05-30 |