0000000000870142

AUTHOR

Manuel Kuhn

0000-0003-2210-9130

showing 2 related works from this author

Fear expression and return of fear following threat instruction with or without direct contingency experience

2016

Prior research showed that mere instructions about the contingency between a conditioned stimulus (CS) and an unconditioned stimulus (US) can generate fear reactions to the CS. Little is known, however, about the extent to which actual CS-US contingency experience adds anything beyond the effect of contingency instructions. Our results extend previous studies on this topic in that it included fear potentiated startle as an additional dependent variable and examined return of fear (ROF) following reinstatement. We observed that CS-US pairings can enhance fear reactions beyond the effect of contingency instructions. Moreover, for all measures of fear, instructions elicited immediate fear reac…

AdultMaleReflex StartleREFLEXSkin conductance responsePoison controlExperimental and Cognitive PsychologyRELEVANT STIMULIInstructionsFear-potentiated startle050105 experimental psychology03 medical and health sciences0302 clinical medicineArts and Humanities (miscellaneous)Conditioning PsychologicalDevelopmental and Educational PsychologymedicineHumansANXIETY0501 psychology and cognitive sciencesSituational ethicsELECTRODERMAL RESPONSESPhobiasACQUISITION05 social sciencesClassical conditioningHUMANSGalvanic Skin ResponseExtinction (psychology)LEARNED FEARFearFear potentiated startlemedicine.diseaseEXTINCTIONAnxietyFemalemedicine.symptomContingencyPsychologySocial psychology030217 neurology & neurosurgeryPOTENTIATED STARTLEPHOBIASConditioning
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Mismatch or allostatic load? Timing of life adversity differentially shapes gray matter volume and anxious temperament

2015

Traditionally, adversity was defined as the accumulation of environmental events (allostatic load). Recently however, a mismatch between the early and the later (adult) environment (mismatch) has been hypothesized to be critical for disease development, a hypothesis that has not yet been tested explicitly in humans. We explored the impact of timing of life adversity (childhood and past year) on anxiety and depression levels (N = 833) and brain morphology (N = 129). Both remote (childhood) and proximal (recent) adversities were differentially mirrored in morphometric changes in areas critically involved in emotional processing (i.e. amygdala/hippocampus, dorsal anterior cingulate cortex, res…

0301 basic medicineMalestressful life eventschildhood maltreatmentEmotionsAnxietySocial EnvironmentDevelopmental psychology0302 clinical medicineGray MatterVBMChildadversitymedia_commonDepressionAdult Survivors of Child AbuseAllostasisBrainGeneral MedicineOrgan SizeMagnetic Resonance ImagingAllostatic loadmedicine.anatomical_structureAllostasisAnxietyFemalemedicine.symptomPsychologymismatchallostatic loadAdultCognitive Neurosciencemedia_common.quotation_subjectExperimental and Cognitive PsychologyAffect (psychology)AmygdalaLife Change Events03 medical and health sciencesYoung AdultmedicineHumansddc:610TemperamentAnterior cingulate cortexBrain morphometryOriginal ArticlesImage Enhancement030104 developmental biologyTemperament030217 neurology & neurosurgerySocial Cognitive and Affective Neuroscience
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