0000000000878731

AUTHOR

Markus Brugger

showing 10 related works from this author

Mechanisms of Electron-Induced Single-Event Upsets in Medical and Experimental Linacs

2018

In this paper, we perform an in-depth analysis of the single-event effects observed during testing at medical electron linacs and an experimental high-energy electron linac. For electron irradiations, the medical linacs are most commonly used due to their availability and flexibility. Whereas previous efforts were made to characterize the cross sections at higher energies, where the nuclear interaction cross section is higher, the focus of this paper is on the complete overview of relevant electron energies. Irradiations at an electron linac were made with two different devices, with a large difference in feature size. The irradiations at an experimental linac were performed with varying en…

010302 applied physicsNuclear and High Energy PhysicsMaterials scienceta114010308 nuclear & particles physicselectronsElectron linacElectronhiukkaskiihdyttimetelektronitparticle accelerators01 natural sciencesLinear particle acceleratorNuclear physicsNuclear interactionradiation physicsCross section (physics)säteilyfysiikkaNuclear Energy and Engineering0103 physical sciencesElectrical and Electronic EngineeringEvent (particle physics)IEEE Transactions on Nuclear Science
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Mechanisms of Electron-Induced Single-Event Latchup

2019

In this paper, possible mechanisms by which electrons can induce single-event latchups in electronics are discussed. The energy deposition and the nuclear fragments created by electrons in silicon are analyzed in this context. The cross section enhancement effect in the presence of high-Z materials is discussed. First experimental results of electron-induced latchups are shown in static random access memory devices with low linear energy transfer thresholds. The radiation hardness assurance implications and future work are discussed.

Nuclear and High Energy PhysicsWork (thermodynamics)Materials scienceSiliconchemistry.chemical_elementLinear energy transferContext (language use)Electronhiukkaskiihdyttimetelektronit01 natural sciencesradiation physics0103 physical sciencesElectronicsStatic random-access memoryDetectors and Experimental TechniquesElectrical and Electronic EngineeringRadiation hardeningta114010308 nuclear & particles physicsbusiness.industryelectronsparticle acceleratorssäteilyfysiikkaNuclear Energy and EngineeringchemistryOptoelectronicsbusinessIEEE Transactions on Nuclear Science
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CERN IRRADIATION FACILITIES.

2017

CERN provides unique irradiation facilities for applications in dosimetry, metrology, intercomparison of radiation protection devices, benchmark of Monte Carlo codes and radiation damage studies to electronics.

säteilytysPhysics::Instrumentation and DetectorsComputer scienceNuclear engineeringPhysics::Medical PhysicsMonte Carlo methodRadiation Dosage01 natural sciences030218 nuclear medicine & medical imagingradiation physics03 medical and health sciences0302 clinical medicineRadiation ProtectionRadiation Monitoring0103 physical sciencesRadiation damageDosimetryHumansRadiology Nuclear Medicine and imagingComputer SimulationIrradiationNeutronsRadiationLarge Hadron Colliderta114irradiationRadiological and Ultrasound Technology010308 nuclear & particles physicsbusiness.industryPublic Health Environmental and Occupational HealthGeneral MedicineMetrologysäteilyfysiikkaBenchmark (computing)Physics::Accelerator PhysicsRadiation protectionbusinessMonte Carlo MethodRadiation protection dosimetry
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Direct Ionization Impact on Accelerator Mixed-Field Soft-Error Rate

2020

We investigate, through measurements and simulations, the possible direct ionization impact on the accelerator soft-error rate (SER), not considered in standard qualification approaches. Results show that, for a broad variety of state-of-the-art commercial components considered in the 65-16-nm technological range, indirect ionization is still expected to dominate the overall SER in the accelerator mixed-field. However, the derived critical charges of the most sensitive parts, corresponding to ~0.7 fC, are expected to be at the limit of rapid direct ionization dominance and soft-error increase.

PhysicsNuclear and High Energy PhysicsRange (particle radiation)Large Hadron ColliderField (physics)010308 nuclear & particles physicsMonte Carlo methodAccelerators and Storage Rings01 natural sciences7. Clean energyComputational physicsSoft errorNuclear Energy and EngineeringIonization0103 physical sciencesNeutronLimit (mathematics)Electrical and Electronic EngineeringIEEE Transactions on Nuclear Science
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High-Energy Electron-Induced SEUs and Jovian Environment Impact

2017

We present experimental evidence of electron-induced upsets in a reference European Space Agency (ESA) single event upset (SEU) monitor, induced by a 200-MeV electron beam at the Very energetic Electronic facility for Space Planetary Exploration in harsh Radiation environments facility at CERN. Comparison of experimental cross sections and simulated cross sections is shown and the differences are analyzed. Possible secondary contributions to the upset rate by neutrons, flash effects, and cumulative dose effects are discussed, showing that electronuclear reactions are the expected SEU mechanism. The ESA Jupiter Icy Moons Explorer mission, to be launched in 2022, presents a challenging radiat…

Nuclear and High Energy Physics02 engineering and technologyRadiationspace technologyelektronit01 natural sciencesUpsetJovianNuclear physicsJupitersymbols.namesakeradiation physics0103 physical sciences0202 electrical engineering electronic engineering information engineeringElectrical and Electronic EngineeringavaruustekniikkaPhysicsSpacecraftta114010308 nuclear & particles physicsbusiness.industryionising radiationionisoiva säteilyelectrons020202 computer hardware & architectureNuclear Energy and EngineeringsäteilyfysiikkaSingle event upsetVan Allen radiation beltPhysics::Space PhysicsElectromagnetic shieldingsymbolsAstrophysics::Earth and Planetary AstrophysicsAtomic physicsbusinessIEEE Transactions on Nuclear Science
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Combined Temperature Radiation Effects and Influence of Drawing Conditions on Phosphorous‐Doped Optical Fibers

2018

International audience; This work focuses on the effects of high dose ionizing radiation, up to 10 MGy(SiO2), on P‐doped multimode optical fibers (OF) at different irradiation temperatures. The investigation is based on two complementary experimental techniques: radiation‐induced attenuation (RIA) measurements and electron paramagnetic resonance (EPR). The latter technique allows measuring the P1, P2, metastable‐POHC and stable‐POHC defects. Three OF samples are drawn from the same preform to evaluate the influence of changing their drawing conditions of the OFs on the radiation responses. This first study is performed under X‐rays at room temperature. The results are compared with the ones…

[PHYS]Physics [physics]Materials scienceOptical fiber010308 nuclear & particles physicsbusiness.industryDoping02 engineering and technologySurfaces and InterfacesRadiation021001 nanoscience & nanotechnologyCondensed Matter Physics01 natural sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic Materialslaw.invention[SPI]Engineering Sciences [physics]law0103 physical sciencesirradiation effects optical fibersMaterials ChemistryOptoelectronicsElectrical and Electronic Engineering0210 nano-technologybusinessphysica status solidi (a)
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Sorafenib maintenance after allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia with FLT3-internal tandem duplication mutat…

2020

PURPOSE Despite undergoing allogeneic hematopoietic stem cell transplantation (HCT), patients with acute myeloid leukemia (AML) with internal tandem duplication mutation in the FMS-like tyrosine kinase 3 gene ( FLT3-ITD) have a poor prognosis, frequently relapse, and die as a result of AML. It is currently unknown whether a maintenance therapy using FLT3 inhibitors, such as the multitargeted tyrosine kinase inhibitor sorafenib, improves outcome after HCT. PATIENTS AND METHODS In a randomized, placebo-controlled, double-blind phase II trial (SORMAIN; German Clinical Trials Register: DRKS00000591), 83 adult patients with FLT3-ITD–positive AML in complete hematologic remission after HCT were r…

SorafenibFLT3 Internal Tandem DuplicationCancer ResearchMyeloidbusiness.industrymedicine.medical_treatmentMyeloid leukemiaHematopoietic stem cell transplantationmedicine.diseaseTransplantationLeukemiamedicine.anatomical_structureOncologyhemic and lymphatic diseasesmedicineCancer researchNeoplasmbusinessmedicine.drug
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Mono-energetic electron induced single-event effects at the VESPER facility

2016

We present experimental evidence of electron induced upsets in a reference ESA SEU monitor, the SEU based particle detector, induced by 200 MeV electron beam at the VESPER facility at CERN. Comparison of experimental cross sections and simulated cross sections are shown and the differences are analyzed. Possible secondary contributions to the upset rate by neutrons and cumulative dose effects are discussed, showing that electronuclear reactions are the expected SEU mechanism. Insight is given as to possible overall electron contribution to the upset rates in the Jovian radiation environment inside a typical spacecraft shielding are evaluated.

PhysicsLarge Hadron Collider010308 nuclear & particles physicsElectronRadiation01 natural sciencesUpsetParticle detectorNuclear physics0103 physical sciencesElectromagnetic shieldingCathode rayNeutron010306 general physics2016 16th European Conference on Radiation and Its Effects on Components and Systems (RADECS)
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Mechanisms of Electron-Induced Single Event Upsets in Medical and Experimental Linacs

2018

In this paper, we perform an in-depth analysis of the single-event effects observed during testing at medical electron linacs and an experimental high-energy electron linac. For electron irradiations, the medical linacs are most commonly used due to their availability and flexibility. Whereas previous efforts were made to characterize the cross sections at higher energies, where the nuclear interaction cross section is higher, the focus of this paper is on the complete overview of relevant electron energies. Irradiations at an electron linac were made with two different devices, with a large difference in feature size. The irradiations at an experimental linac were performed with varying en…

radiation physicssäteilyfysiikkaelectronshiukkaskiihdyttimetelektronitparticle accelerators
researchProduct

Mechanisms of Electron-Induced Single Event Latchup

2019

In this paper, possible mechanisms by which electrons can induce single-event latchups in electronics are discussed. The energy deposition and the nuclear fragments created by electrons in silicon are analyzed in this context. The cross section enhancement effect in the presence of high-Z materials is discussed. First experimental results of electron-induced latchups are shown in static random access memory devices with low linear energy transfer thresholds. The radiation hardness assurance implications and future work are discussed. peerReviewed

radiation physicssäteilyfysiikkaelectronshiukkaskiihdyttimetelektronitparticle accelerators
researchProduct