0000000000883810
AUTHOR
Pilar Miró
showing 2 related works from this author
Sequential recruitment of the mRNA decay machinery to the iron-regulated protein Cth2 in Saccharomyces cerevisiae
2020
Post-transcriptional factors importantly contribute to the rapid and coordinated expression of the multiple genes required for the adaptation of living organisms to environmental stresses. In the model eukaryote Saccharomyces cerevisiae, a conserved mRNA-binding protein, known as Cth2, modulates the metabolic response to iron deficiency. Cth2 is a tandem zinc-finger (TZF)-containing protein that co-transcriptionally binds to adenine/uracil-rich elements (ARE) present in the 3′-untranslated region of iron-related mRNAs to promote their turnover. The nuclear binding of Cth2 to mRNAs via its TZFs is indispensable for its export to the cytoplasm. Although Cth2 nucleocytoplasmic transport is ess…
Glucose uptake in germinating Aspergillus nidulans conidia: involvement of the creA and sorA genes
2003
d-Glucose uptake in germinating wild-typeAspergillus nidulansconidia is an energy-requiring process mediated by at least two transport systems of differing affinities for glucose: a low-affinity system (Km∼1·4 mM) and a high-affinity system (Km∼16 μM). The low-affinity system is inducible by glucose; the high-affinity system is subject to glucose repression effected by the carbon catabolite repressor CreA and is absent insorA3mutant conidia, which exhibit resistance tol-sorbose toxicity. An intermediate-affinity system (Km∼400 μM) is present insorA3conidia germinating in derepressing conditions.creAderepressed mutants show enhanced sensitivity tol-sorbose. The high-affinity uptake system ap…