Polyalthidin:  New Prenylated Benzopyran Inhibitor of the Mammalian Mitochondrial Respiratory Chain

Polyalthidin (3), a new benzopyran derivative, was isolated from the stem bark of Polyalthia cerasoides. Its structure was established on the basis of chemical and spectral evidence. Polyalthidin has showed potent biological activity as an inhibitor of the mammalian mitochondrial respiratory chain.