A Search for IceCube Events in the Direction of ANITA Neutrino Candidates

During the first three flights of the Antarctic Impulsive Transient Antenna (ANITA) experiment, the collaboration detected several neutrino candidates. Two of these candidate events were consistent with an ultra-high-energy up-going air shower and compatible with a tau neutrino interpretation. A third neutrino candidate event was detected in a search for Askaryan radiation in the Antarctic ice, although it is also consistent with the background expectation. The inferred emergence angle of the first two events is in tension with IceCube and ANITA limits on isotropic cosmogenic neutrino fluxes. Here, we test the hypothesis that these events are astrophysical in origin, possibly caused by a po…

IceCube search for neutrinos coincident with compact binary mergers from LIGO-Virgo's first gravitational-wave transient catalog

Using the IceCube Neutrino Observatory, we search for high-energy neutrino emission coincident with compact binary mergers observed by the LIGO and Virgo gravitational-wave (GW) detectors during their first and second observing runs. We present results from two searches targeting emission coincident with the sky localization of each GW event within a 1000 s time window centered around the reported merger time. One search uses a model-independent unbinned maximum-likelihood analysis, which uses neutrino data from IceCube to search for pointlike neutrino sources consistent with the sky localization of GW events. The other uses the Low-Latency Algorithm for Multi-messenger Astrophysics, which …

Final results on $${}^\mathbf{82 }{\hbox {Se}}$$ 82Se double beta decay to the ground state of $${}^\mathbf{82 }{\hbox {Kr}}$$ 82Kr from the NEMO-3 experiment

Using data from the NEMO-3 experiment, we have measured the two-neutrino double beta decay ($$2\nu \beta \beta $$ 2νββ ) half-life of $$^{82}$$ 82 Se as $$T_{\smash {1/2}}^{2\nu } \!=\! \left[ 9.39 \pm 0.17\left( \text{ stat }\right) \pm 0.58\left( \text{ syst }\right) \right] \times 10^{19}$$ T1/22ν=9.39±0.17stat±0.58syst×1019 y under the single-state dominance hypothesis for this nuclear transition. The corresponding nuclear matrix element is $$\left| M^{2\nu }\right| = 0.0498 \pm 0.0016$$ M2ν=0.0498±0.0016 . In addition, a search for neutrinoless double beta decay ($$0\nu \beta \beta $$ 0νββ ) using 0.93 kg of $$^{82}$$ 82 Se observed for a total of 5.25 y has been conducted and no evide…

Searches for Sterile Neutrinos with the IceCube Detector

The IceCube neutrino telescope at the South Pole has measured the atmospheric muon neutrino spectrum as a function of zenith angle and energy in the approximate 320 GeV to 20 TeV range, to search for the oscillation signatures of light sterile neutrinos. No evidence for anomalous $\nu_\mu$ or $\bar{\nu}_\mu$ disappearance is observed in either of two independently developed analyses, each using one year of atmospheric neutrino data. New exclusion limits are placed on the parameter space of the 3+1 model, in which muon antineutrinos would experience a strong MSW-resonant oscillation. The exclusion limits extend to $\mathrm{sin}^2 2\theta_{24} \leq$ 0.02 at $\Delta m^2 \sim$ 0.3 $\mathrm{eV}^…

Performance of existing definitions and tests for the diagnosis of invasive aspergillosis in critically ill, non-neutropenic, adult patients: An update including COVID-19 data.

Detailed studies of $$^{100}$$ 100 Mo two-neutrino double beta decay in NEMO-3

The full data set of the NEMO-3 experiment has been used to measure the half-life of the two-neutrino double beta decay of $$^{100}$$ 100 Mo to the ground state of $$^{100}$$ 100 Ru, $$T_{1/2} = \left[ 6.81 \pm 0.01\,\left( \text{ stat }\right) ^{+0.38}_{-0.40}\,\left( \text{ syst }\right) \right] \times 10^{18}$$ T1/2=6.81±0.01stat-0.40+0.38syst×1018 year. The two-electron energy sum, single electron energy spectra and distribution of the angle between the electrons are presented with an unprecedented statistics of $$5\times 10^5$$ 5×105 events and a signal-to-background ratio of $$\sim $$ ∼ 80. Clear evidence for the Single State Dominance model is found for this nuclear transition. Limit…

Detailed studies of $^{100}$Mo two-neutrino double beta decay in NEMO-3

The full data set of the NEMO-3 experiment has been used to measure the half-life of the two-neutrino double beta decay of $^{100}$Mo to the ground state of $^{100}$Ru, $T_{1/2} = \left[ 6.81 \pm 0.01\,\left(\mbox{stat}\right) ^{+0.38}_{-0.40}\,\left(\mbox{syst}\right) \right] \times10^{18}$ y. The two-electron energy sum, single electron energy spectra and distribution of the angle between the electrons are presented with an unprecedented statistics of $5\times10^5$ events and a signal-to-background ratio of ~80. Clear evidence for the Single State Dominance model is found for this nuclear transition. Limits on Majoron emitting neutrinoless double beta decay modes with spectral indices of …

Characteristics of the diffuse astrophysical electron and Tau neutrino flux with six years of IceCube high energy cascade data

We report on the first measurement of the astrophysical neutrino flux using particle showers (cascades) in IceCube data from 2010-2015. Assuming standard oscillations, the astrophysical neutrinos in this dedicated cascade sample are dominated (∼90%) by electron and tau flavors. The flux, observed in the sensitive energy range from 16 TeV to 2.6 PeV, is consistent with a single power-law model as expected from Fermi-type acceleration of high energy particles at astrophysical sources. We find the flux spectral index to be γ=2.53±0.07 and a flux normalization for each neutrino flavor of φastro=1.66-0.27+0.25 at E0=100 TeV, in agreement with IceCube's complementary muon neutrino results and wit…

HACD1, a regulator of membrane composition and fluidity, promotes myoblast fusion and skeletal muscle growth

International audience; The reduced diameter of skeletal myofibres is a hallmark of several congenital myopathies, yet the underlying cellular and molecular mechanisms remain elusive. In this study, we investigate the role of HACD1/PTPLA, which is involved in the elongation of the very long chain fatty acids, in muscle fibre formation. In humans and dogs, HACD1 deficiency leads to a congenital myopathy with fibre size disproportion associated with a generalized muscle weakness. Through analysis of HACD1-deficient Labradors, Hacd1-knockout mice, and Hacd1-deficient myoblasts, we provide evidence that HACD1 promotes myoblast fusion during muscle development and regeneration. We further demons…

Combined sensitivity to the neutrino mass ordering with JUNO, the IceCube Upgrade, and PINGU

Physical review / D 101(3), 032006 (1-19) (2020). doi:10.1103/PhysRevD.101.032006

Computational Techniques for the Analysis of Small Signals in High-Statistics Neutrino Oscillation Experiments

The current and upcoming generation of Very Large Volume Neutrino Telescopes – collecting unprecedented quantities of neutrino events – can be used to explore subtle effects in oscillation physics, such as (but not restricted to) the neutrino mass ordering. The sensitivity of an experiment to these effects can be estimated from Monte Carlo simulations. With the high number of events that will be collected, there is a trade-off between the computational expense of running such simulations and the inherent statistical uncertainty in the determined values. In such a scenario, it becomes impractical to produce and use adequately-sized sets of simulated events with traditional methods, such as M…

Constraints on Minute-Scale Transient Astrophysical Neutrino Sources

High-energy neutrino emission has been predicted for several short-lived astrophysical transients including gamma-ray bursts (GRBs), core-collapse supernovae with choked jets, and neutron star mergers. IceCube's optical and x-ray follow-up program searches for such transient sources by looking for two or more muon neutrino candidates in directional coincidence and arriving within 100 s. The measured rate of neutrino alerts is consistent with the expected rate of chance coincidences of atmospheric background events and no likely electromagnetic counterparts have been identified in Swift follow-up observations. Here, we calculate generic bounds on the neutrino flux of short-lived transient so…

Search for neutrinoless double-beta decay ofMo100with the NEMO-3 detector

We report the results of a search for the neutrinoless double-$\beta$ decay (0$\nu\beta\beta$) of $^{100}$Mo, using the NEMO-3 detector to reconstruct the full topology of the final state events. With an exposure of 34.7 kg.y, no evidence for the 0$\nu\beta\beta$ signal has been found, yielding a limit for the light Majorana neutrino mass mechanism of $T_{1/2}(0\nu\beta\beta)>1.1 \times 10^{24}$ years (90% C.L.) once both statistical and systematic uncertainties are taken into account. Depending on the Nuclear Matrix Elements this corresponds to an upper limit on the Majorana effective neutrino mass of $ < 0.3-0.8$ eV (90% C.L.). Constraints on other lepton number violating mechanisms of 0$…