0000000000958920

AUTHOR

Giuseppe Guanti

showing 2 related works from this author

Thiophene series. Substituent effect on thiophenoxy debromination of various 2-nitro-3-bromo-5-X-thiophenes

1970

The kinetics of the reaction of a series of 2-nitro-3-bromo-5-X-thiophenes with sodium thiophenoxide in methanol were determined. The plot of log k against σ-values gave ρ-value + 4.51 at 20°. Good correlation was observed pointing out the validity of the Hammett relationship for reactions occurring directly on the thiophene ring at the β-position with respect to the heteroatom.

SodiumOrganic ChemistryKineticsHeteroatomSubstituentchemistry.chemical_elementRing (chemistry)Medicinal chemistrychemistry.chemical_compoundchemistryNitroThiopheneOrganic chemistryMethanolJournal of Heterocyclic Chemistry
researchProduct

The behaviour of 2-nitrothiophene and of 3-nitrothiophene with some nucleophiles

1975

The reactivity of 2-nitrothiophene (1) and of 3-nitrothiophene (II) with some nucleophiles has been studied. According to calculated electronic densities I can receive nucleophilic attack at C3 and C5 depending on the nucleophile used, but II only at C2. With N-lithium piperidine both I and II also give coupling products (VII and XI respectively) of the hithienyl type.

chemistry.chemical_compoundNucleophileChemistryOrganic ChemistryOrganic chemistryReactivity (chemistry)PiperidineMedicinal chemistryJournal of Heterocyclic Chemistry
researchProduct