0000000000960493
AUTHOR
P. Chen
Observations of Bs0→ψ(2S)η and B(s)0→ψ(2S)π+π− decays
First observations of the $B^0_s \rightarrow \psi(2S) \eta$, $B^0 \rightarrow \psi(2S) \pi^+ \pi^-$ and $B^0_s \rightarrow \psi(2S) \pi^+ \pi^-$ decays are made using a dataset corresponding to an integrated luminosity of 1.0~$fb^{-1}$ collected by the LHCb experiment in proton-proton collisions at a centre-of-mass energy of $\sqrt{s}=7$ TeV. The ratios of the branching fractions of each of the $\psi(2S)$ modes with respect to the corresponding $J/\psi$ decays are \[ \frac{\mathcal{B}(B^0_s \rightarrow \psi(2S) \eta) }{\mathcal{B}(B^0_s \rightarrow J/\psi \eta)} =0.83\pm0.14\,(stat)\pm0.12\,(syst)\pm0.02\,(\mathcalB}), \] \[ \frac{\mathcal{B}(B^0 \rightarrow \psi(2S) \pi^+ \pi^-)}{\mathcal{…
The Ultra-Fast Flash Observatory's space GRB mission and science
AbstractThe Ultra-Fast Flash Observatory (UFFO) is a space mission to detect the early moments of an explosion from Gamma-ray bursts (GRBs), thus enhancing our understanding of the GRB mechanism. It consists of the UFFO Burst & Trigger telescope (UBAT) for the recognition of GRB positions using hard X-ray from GRBs. It also contains the Slewing Mirror Telescope (SMT) for the fast detection of UV-optical photons from GRBs. It is designed to begin the UV-optical observations in less than a few seconds after the trigger. The UBAT is based on a coded-mask X-ray camera with a wide field of view (FOV) and is composed of the coded mask, a hopper and a detector module. The SMT has a fast rotata…
Ultra-Fast Flash Observatory for detecting the early photons from gamma-ray bursts
Gamma-ray bursts (GRBs) are the most luminous transient events with short intense flashes that have been detected in random directions in the sky once or twice per day. Their durations have been measured in seconds, especially short GRBs with duration of < 2 sec. The Ultra-Fast Flash Observatory (UFFO) space mission aims to detect the earliest moments of an explosion which presents the nature of GRBs, resulting into the enhancement of GRB mechanism understanding. The UFFO consists of a couple of wide Field-of-View (FOV) trigger telescopes, a narrow-FOV Slewing Mirror Telescope (SMT) for the fast measurement of the UV-optical photons from GRBs, and a gamma-ray monitor for energy measurement.…
Feasibility and physics potential of detecting $^8$B solar neutrinos at JUNO
The Jiangmen Underground Neutrino Observatory (JUNO) features a 20 kt multi-purpose underground liquid scintillator sphere as its main detector. Some of JUNO's features make it an excellent location for 8B solar neutrino measurements, such as its low-energy threshold, high energy resolution compared with water Cherenkov detectors, and much larger target mass compared with previous liquid scintillator detectors. In this paper, we present a comprehensive assessment of JUNO's potential for detecting 8B solar neutrinos via the neutrino-electron elastic scattering process. A reduced 2 MeV threshold for the recoil electron energy is found to be achievable, assuming that the intrinsic radioactive …
Precision measurement of D meson mass differences
Using three- and four-body decays of D mesons produced in semileptonic b-hadron decays, precision measurements of D meson mass differences are made together with a measurement of the D-0 mass. The measurements are based on a dataset corresponding to an integrated luminosity of 1.0 fb(-1) collected in pp collisions at 7 TeV. Using the decay D-0 -> K+K-K-pi(+), the D-0 mass is measured to be M(D-0) = 1864.75 +/- 0.15 (stat) +/- 0.11 (syst) MeV/c(2). The mass differences M(D+) - M(D-0) = 4.76 +/- 0.12 (stat) +/- 0.07 (syst) MeV/c(2), M(D-s(+)) - M(D+) = 98.68 +/- 0.03 (stat) +/- 0.04 (syst) MeV/c(2) are measured using the D-0 -> K+K-pi(+)pi(-) and D-(s)(+) -> K+K-pi(+) modes.
Cosmic ray effect on the X-ray Trigger Telescope of UFFO/Lomonosov using YSO scintillation crystal array in space
UFFO Burst Alert and Trigger telescope (UBAT) is the X-ray trigger telescope of UFFO/Lomonosov to localize X-ray source with coded mask method and X-ray detector. Its X-ray detector is made up of 36 8×8 pixels Yttrium OxyorthoSilicate (Y2SiO5:Ce, YSO) scintillation crystal arrays and 36 64-channel Multi-Anode PhotoMultiplier Tubes (MAPMTs) for space mission. Its effective detection area is 161cm2 and energy range is several keV to 150 keV. It was successfully launched in April 28, 2016. In several calibration run, we got several X-ray background data. We already knew X-ray background flux is 2-3 counts/cm2/sec in space. However our X-ray background data shows approximately 7-8 times higher …
SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study
Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…
Slewing mirror telescope of the UFFO-pathfinder: first report on performance in space
To observe the early optical emissions from gamma ray bursts (GRBs), we built the Slew Mirror Telescope. It utilizes a 150 mm motorized mirror to redirect incoming photons from astrophysical objects within seconds and to track them as compensating satellite movements. The SMT is a major component of the UFFO-pathfinder payload, which was launched on April 28, 2016, onboard the Lomonosov satellite. For the first time, the slewing mirror system has been proven for the precision tracking of astrophysical objects during space operation. We confirmed that the SMT has 1.4 seconds of response time to the X-gamma-ray trigger, and is able to compensate for satellite drift and to track astrophysical …
A novel form of ataxia oculomotor apraxia characterized by oxidative stress and apoptosis resistance
Several different autosomal recessive genetic disorders characterized by ataxia with oculomotor apraxia (AOA) have been identified with the unifying feature of defective DNA damage recognition and/or repair. We describe here the characterization of a novel form of AOA showing increased sensitivity to agents that cause single-strand breaks (SSBs) in DNA but having no gross defect in the repair of these breaks. Evidence for the presence of residual SSBs in DNA was provided by dramatically increased levels of poly (ADP-ribose)polymerase (PARP-1) auto-poly (ADP-ribosyl)ation, the detection of increased levels of reactive oxygen/nitrogen species (ROS/RNS) and oxidative damage to DNA in the patie…
Differential branching fraction and angular analysis of the decay $B^{0} \to K^{*0} \mu^{+}\mu^{-}$
The angular distribution and differential branching fraction of the decay B-0 -> K*(0)mu(+)mu(-) are studied using a data sample, collected by the LHCb experiment in pp collisions at root s = 7 TeV, corresponding to an integrated luminosity of 1.0 fb(-1). Several angular observables are measured in bins of the dimuon invariant mass squared, q(2). A first measurement of the zero-crossing point of the forward-backward asymmetry of the dimuon system is also presented. The zero-crossing point is measured to be q(0)(2) = 4.9 +/- 0.9 GeV2/c(4), where the uncertainty is the sum of statistical and systematic uncertainties. The results are consistent with the Standard Model predictions.
Search for direct CP violation in D0→h−h+ modes using semileptonic B decays
A search for direct CP violation in D0 -> h- h+ (where h=K or pi) is presented using data corresponding to an integrated luminosity of 1.0 fb^-1 collected in 2011 by LHCb in pp collisions at a centre-of-mass energy of 7 TeV. The analysis uses D0 mesons produced in inclusive semileptonic b-hadron decays to the D0 mu X final state, where the charge of the accompanying muon is used to tag the flavour of the D0 meson. The difference in the CP-violating asymmetries between the two decay channels is measured to be Delta A_CP = A_CP(K-K+) - A_CP(pi-pi+) = (0.49 +- 0.30 (stat) +- 0.14 (syst)) % . This result does not confirm the evidence for direct CP violation in the charm sector reported in other…
Measurements of the Λb0→J/ψΛ decay amplitudes and the Λb0 polarisation in pp collisions at s=7 TeV
An angular analysis of Λ0b→J/ψΛ decays is performed using a data sample corresponding to 1.0 fb−1 collected in pp collisions at √s=7 TeV with the LHCb detector at the LHC. A parity violating asymmetry parameter characterising the Λ0b→J/ψΛ decay of 0.05±0.17±0.07 and a Λ0b transverse production polarisation of 0.06±0.07±0.02 are measured, where the first uncertainty is statistical and the second systematic.
Comparison cosmic ray irradiation simulation and particle beam test on UFFO Burst Alert & Trigger telescope(UBAT) detectors
Ultra-Fast Flash Observatory pathfinder(UFFO-p) was launched onboard Lomonosov on 28th of April, 2016, and now is under various types of calibration for detection of Gamma Ray Bursts (GRBs). Since last September UFFO-p has taken X-ray data in space with UFFO Burst Alert & Trigger telescope (UBAT), those X-rays are mostly diffused backgrounds however, the rate turns out to be higher than expected by a factor of three. We assumed cosmic rays can contribute by making the count rate higher. We did such a simulation to investigate the effect of cosmic rays. In December 2016, we irradiated fragmented high energy heavy ions at CERN on the UBAT detector. We will report the result of comparison betw…
ULTRA-FAST FLASH OBSERVATORY (UFFO) FOR OBSERVATION OF EARLY PHOTONS FROM GAMMA RAY BURSTS
I.H. Park, S. Ahmad, P. Barrillon, S. Brandt, C. Budtz-Jorgensen, A.J. Castro-Tirado, P. Chen, Y.J. Choi, P. Connell, S. Dagoret-Campagne, C. Eyles, B. Grossan, M.–H.A. Huang, A. Jung, S. Jeong, J.E. Kim, M.B. Kim, S.-W. Kim, Y.W. Kim, A.S. Krasnov, J. Lee, H. Lim, E.V. Linder, T.–C. Liu, N. Lund, K.W. Min, G.W. Na, J.W. Nam, M.I. Panasyuk, J. Ripa, V. Reglero, J.M. Rodrigo, G.F. Smoot, J.E. Suh, S. Svertilov, N. Vedenkin, M.–Z. Wang, I. Yashin Ewha Womans University, Seoul, Korea University of Paris-Sud 11, Orsay, France Technical University of Denmark, Copenhagen, Denmark Instituto de Astrofisica de Andalucia CSIC, Granada, Spain National Taiwan University, Taipei, Taiwan Korea Advanced I…
In-Situ Calibration of UFFO/Lomonosov for Observation of GRBs
The UFFO/Lomonosov has been successfully launched into Sun synchronous orbit and is operational through tests and calibrations since its launch on Apr. 28, 2016. As a pathfinder of UFFO, it will be the first space instrument to use a fast slewing mirror which reduce the trigger latency of optical telescope, less than a second, to explore early time domain of GRB evolution. In this article, we will report in detail the first mission, UFFO/Lomonosov, for the rapid response to observe early photons from GRBs in orbit.
Searches for violation of lepton flavour and baryon number in tau lepton decays at LHCb
Searches for the lepton flavour violating decay tau(-) -> mu(-)mu(+)mu(-) and the lepton flavour and baryon number violating decays tau(-) -> (p) over bar mu(+)mu(-) and tau(-) -> p mu(-)mu(-) have been carried out using proton-proton collision data, corresponding to an integrated luminosity of 1.0 fb(-1), taken by the LHCb experiment at root s = 7 TeV. No evidence has been found for any signal, and limits have been set at 90% confidence level on the branching fractions: B(tau(-) -> mu(-)mu(+)mu(-) mu(+)mu(-)) p mu(-)mu(-)) (p) over bar mu(+)mu(-) and tau(-) -> p mu(-)mu(-) decay modes represent the first direct experimental limits on these channels.
Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error
Corneal curvature, a highly heritable trait, is a key clinical endophenotype for myopia - a major cause of visual impairment and blindness in the world. Here we present a trans-ethnic meta-analysis of corneal curvature GWAS in 44,042 individuals of Caucasian and Asian with replication in 88,218 UK Biobank data. We identified 47 loci (of which 26 are novel), with population-specific signals as well as shared signals across ethnicities. Some identified variants showed precise scaling in corneal curvature and eye elongation (i.e. axial length) to maintain eyes in emmetropia (i.e. HDAC11/FBLN2 rs2630445, RBP3 rs11204213); others exhibited association with myopia with little pleiotropic effects …
Determination of the $X(3872)$ meson quantum numbers
The quantum numbers of the X(3872) meson are determined to be J(PC) = 1(++) based on angular correlations in B+ -> X(3872)K+ decays, where X(3872) -> pi(+) pi(-) j/psi and J/psi -> pi(+) mu(-). The data correspond to 1.0 fb(-1) of pp collisions collected by the LHCb detector. The only alternative assignment allowed by previous measurements J(PC) = 2(-+) is rejected with a confidence level equivalent to more than 8 Gaussian standard deviations using a likelihood-ratio test in the full angular phase space. This result favors exotic explanations of the X(3872) state.
Observation of the suppressed ADS modes B±→[π±K∓π+π−]DK± and B±→[π±K∓π+π−]Dπ±
An analysis of and B-+/- -> DK +/- and B-+/- -> D pi(+/-) decays is presented where the D meson is reconstructed in the four-body final state K-+/-pi(-/+)pi(+)pi(-). Using LHCb data corresponding to an integrated luminosity of 1.0 fb(-1), first observations are made of the suppressed ADS modes B-+/- ->[pi K-+/-(-/+)pi(+)pi(-)](D)K-+/- and B +/- -> [pi K-+/-(-/+)pi(+)pi(-)](D)pi(+/-) with a significance of 5.1 sigma and greater than 10 sigma, respectively. Measurements of CP asymmetries and CP-conserving ratios of partial widths from this family of decays are also performed. The magnitude of the ratio between the suppressed and favoured B-+/- -> DK +/- amplitudes is determined to be r(B)(K) …
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
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Design and Fabrication of Detector Module for UFFO Burst Alert & Trigger Telescope
The Ultra-Fast Flash Observatory (UFFO) pathfinder is a space mission devoted to the measurement of Gamma-Ray Bursts (GRBs), especially their early light curves which will give crucial information on the progenitor stars and central engines of the GRBs. It consists of two instruments: the UFFO Burst Alert & Trigger telescope (UBAT) for the detection of GRB locations and the Slewing Mirror Telescope (SMT) for the UV/optical afterglow observations, upon triggering by UBAT. The UBAT employs a coded-mask {\gamma}/X-ray camera with a wide field of view (FOV), and is comprised of three parts: a coded mask, a hopper, and a detector module (DM). The UBAT DM consists of a LYSO scintillator crystal a…
Measurement of the effective Bs0→K+K− lifetime
A precise determination of the effective $B_s^0 \rightarrow K^+ K^-$ lifetime can be used to constrain contributions from physics beyond the Standard Model in the $B_s^0$ meson system. Conventional approaches select $B$ meson decay products that are significantly displaced from the $B$ meson production vertex. As a consequence, $B$ mesons with low decay times are suppressed, introducing a bias to the decay time spectrum which must be corrected. This analysis uses a technique that explicitly avoids a lifetime bias by using a neural network based trigger and event selection. Using 1.0 fb$^{-1}$ of data recorded by the LHCb experiment, the effective $B_s^0 \rightarrow K^+ K^-$ lifetime is meas…
K2 light curve alternative analysis of ASASSN-18bt
On 2018 February 4.41, the All-Sky Automated Survey for SuperNovae (ASAS-SN) discovered ASASSN-18bt in the K2 Campaign 16 field. With a redshift of z=0.01098 and a peak apparent magnitude of B_max_=14.31, ASASSN-18bt is the nearest and brightest Supernovae Ia type (SNe Ia) yet observed by the Kepler spacecraft. Here we present the discovery of ASASSN-18bt, the K2 light curve, and prediscovery data from ASAS-SN and the Asteroid Terrestrial-impact Last Alert System. The K2 early-time light curve has an unprecedented 30-minute cadence and photometric precision for an SN Ia light curve, and it unambiguously shows a ~4 day nearly linear phase followed by a steeper rise. Thus, ASASSN-18bt joins a…