Search for pair-production of long-lived heavy charged particles in e+e− annihilation

A search for pair-production of long-lived, heavy, singly-charged particles has been performed with data collected by the ALEPH detector at a centre-of-mass energy of 172 GeV. Data at \sqrt{s} = 161, 136, and 130 GeV are also included to improve the sensitivity to lower masses. No candidate is found in the data. A model-independent 95% confidence level upper limit on the production cross section at 172 GeV of 0.2-0.4pb is derived for masses between 45 and 86 GeV/c^2. This cross section limit implies, assuming the MSSM, a lower limit of 67 (69) GeV/c^2 on the mass of right- (left-) handed long-lived scalar taus or scalar muons and of 86 GeV/c^2 on the mass of long-lived charginos.

Search for charged Higgs bosons in $e^+ e^-$ collisions at centre-of-mass energies from 130 to 172 GeV

Abstract The data collected at centre-of-mass energies ranging from 130 to 172 GeV by ALEPH at LEP, corresponding to an integrated luminosity of 27.5 pb−1, are analysed in a search for pair-produced charged Higgs bosons H±. Three analyses are employed to select the τ + ν τ τ − ν τ , c s τ − ν τ and c s s c final states. No evidence for a signal is found. Mass limits are set as a function of the branching fraction B (τν) for H±→τν. Charged Higgs bosons with masses below 52 GeV/c2 are excluded at 95% C.L. independently of B (τν) , thus significantly improving on existing limits.

Risk factors for hospital readmission of elderly patients

Background: The aim of this study was to identify which factors were associated with a risk of hospital readmission within 3 months after discharge of a sample of elderly patients admitted to internal medicine and geriatric wards. Methods: Of the 1178 patients aged 65 years or more and discharged from one of the 66 wards of the 'Registry Politerapie SIMI (REPOSI)' during 2010, 766 were followed up by phone interview 3 months after discharge and were included in this analysis. Univariate and multivariate logistic regression models were used to evaluate the association of several variables with rehospitalization within 3 months from discharge. Results: Nineteen percent of patients were readmi…

An upper limit for the τ neutrino mass from τ → 5π(π0)ντ decays

An upper limit for the tau-neutrino mass has been determined from the decay tau -> 5pi+- \nu_tau using data collected with the OPAL detector from 1991 to 1995 in e+e- collisions at \sqrt{s} ~ M_Z. A limit of 43.2 MeV at 95% CL is obtained using a two-dimensional method in the 5pi invariant mass and energy distribution from 22 selected events. Combining this result with OPAL's previously published measurement using tau+tau- -> 3h+- \bar{nu}_tau 3h-+ \nu_tau decays, a new combined limit of m_{nu_tau} < 27.6 MeV (95% CL) is obtained.

Adherence to antibiotic treatment guidelines and outcomes in the hospitalized elderly with different types of pneumonia.

none 22 no Background: Few studies evaluated the clinical outcomes of Community Acquired Pneumonia (CAP), Hospital-Acquired Pneumonia (HAP) and Health Care-Associated Pneumonia (HCAP) in relation to the adherence of antibiotic treatment to the guidelines of the Infectious Diseases Society of America (IDSA) and the American Thoracic Society (ATS) in hospitalized elderly people (65 years or older). Methods: Data were obtained from REPOSI, a prospective registry held in 87 Italian internal medicine and geriatric wards. Patients with a diagnosis of pneumonia (ICD-9 480-487) or prescribed with an antibiotic for pneumonia as indication were selected. The empirical antibiotic regimen was defined t…

MEASUREMENT OF ALPHA(S) FROM SCALING VIOLATIONS IN FRAGMENTATION FUNCTIONS IN E(+)E(-) ANNIHILATION

A study of scaling violations in fragmentation functions performed by the ALEPH collaboration at LEP is presented. Data samples enriched in uds, c, b and gluon jets, respectively, together with measurements of the longitudinal and transverse inclusive cross sections are used to extract the fragmentation function for the gluon and for each flavour. The measurements are compared to data from experiments at energies between 22 GeV and 91 GeV and scaling violations consistent with QCD predictions are observed. From this, a measurement of the strong coupling constant alpha(s) (M(z)) = 0.126 +/- 0.009 is obtained.

Joint use of cardio-embolic and bleeding risk scores in elderly patients with atrial fibrillation

Background Scores for cardio-embolic and bleeding risk in patients with atrial fibrillation are described in the literature. However, it is not clear how they co-classify elderly patients with multimorbidity, nor whether and how they affect the physician's decision on thromboprophylaxis. Methods Four scores for cardio-embolic and bleeding risks were retrospectively calculated for ≥ 65 year old patients with atrial fibrillation enrolled in the REPOSI registry. The co-classification of patients according to risk categories based on different score combinations was described and the relationship between risk categories tested. The association between the antithrombotic therapy received and t…

A measurement of |Vcb| from

Abstract From approximately 3 million hadronic decays of Z bosons recorded with the aleph detector at lep , a sample of 410 ± 32 B 0 → D ∗+ l − ν l candidates is selected, where l is either an electron or a muon. The differential decay rate dΓ ( B 0 → D ∗+ l − ν l ) dω from this sample is fitted, yielding a value for the product of the CKM matrix element |Vcb| and the normalisation of the decay form factor at the point of zero recoil of the D∗+ meson F (ω = 1)|Vcb| = (31.4 ± 2.3stat ± 2.5syst) × 10−3. A value for |Vcb| is extracted using theoretical calculations of the form factor normalisation, with the result |Vcb| = (34.5 ± 2.5stat ± 2.7syst ± 1.5theory) × 10−3. From the integrated s the…

Gout, allopurinol intake and clinical outcomes in the hospitalized multimorbid elderly.

Background: Increased serum uric acid has been considered a cardiovascular risk factor but no study has assessed its relation with hospital mortality or length of stay. On the basis of data obtained from a prospective registry, the prevalence of gout/hyperuricemia and its association with these and other clinical parameters was evaluated in an Italian cohort of elderly patients acutely admitted to internal medicine or geriatric wards. Methods: While the prevalence of gout was calculated by counting patients with this diagnosis hyperuricemia was inferred in patients taking allopurinol at hospital admission or discharge, on the assumption that this drug was only prescribed owing to the findin…

Prevalence and Risk Factors Associated with Use of QT-Prolonging Drugs in Hospitalized Older People

Aims: The objective of this study was to evaluate the prevalence of the prescription of QT-prolonging drugs at hospital admission and discharge and the risk factors associated with their use in older people (aged 65 years and older). Methods: Data were obtained from the REPOSI (REgistro POliterapie SIMI [Società Italiana di Medicina Interna]) registry, which enrolled 4035 patients in 2008 (n = 1332), 2010 (n = 1380), and 2012 (n = 1323). Multivariable logistic regression was performed to determine the risk factors independently associated with QT-prolonging drug use. QT-prolonging drugs were classified by the risk of Torsades de Pointes (TdP) (definite, possible, or conditional) acc…

Brain and kidney, victims of atrial microembolism in elderly hospitalized patients? Data from the REPOSI study

Abstract Background It is well known that atrial fibrillation (AF) and chronic kidney disease (CKD) are associated with a higher risk of stroke, and new evidence links AF to cognitive impairment, independently from an overt stroke (CI). Our aim was to investigate, assuming an underlying role of atrial microembolism, the impact of CI and CKD in elderly hospitalized patients with AF. Methods We retrospectively analyzed the data collected on elderly patients in 66 Italian hospitals, in the frame of the REPOSI project. We analyzed the clinical characteristics of patients with AF and different degrees of CI. Multivariate logistic analysis was used to explore the relationship between variables an…

Multimorbidity and polypharmacy in the elderly: Lessons from REPOSI

none 10 no The dramatic demographic changes that are occurring in the third millennium are modifying the mission of generalist professionals such as primary care physicians and internists. Multiple chronic diseases and the related prescription of multiple medications are becoming typical problems and present many challenges. Unfortunately, the available evidence regarding the efficacy of medications has been generated by clinical trials involving patients completely different from those currently admitted to internal medicine: much younger, affected by a single disease and managed in a highly controlled research environment. Because only registries can provide information on drug effectiven…

Searches for Supersymmetry in the photon(s) plus missing energy channels at $\sqrt{s}$ = 161 GeV and 172 GeV

Searches for supersymmetric particles in channels with one or more photons and missing energy have been performed with data collected by the ALEPH detector at LEP. The data consist of 11.1 pb-1 at $\sqrt{s} = 161 GeV$, 1.1 pb-1 at 170 GeV and 9.5 pb-1 at 172 GeV. The e+e- -> nunu+photon cross section is measured. The data are in good agreement with predictions based on the Standard Model, and are used to set upper limits on the cross sections for anomalous photon production. These limits are compared to two different SUSY models and used to set limits on the neutralino mass. A limit of 71 GeV/c^2 at 95% C.L. is set on the mass of the lightest neutralino ($\tau_{\chi_{1}^{0}} \leq $ 3 ns) fo…

Measurement of the Bs0 lifetime and production rate with Ds−ℓ+ combinations in Z decays

Abstract The lifetime of the Bs0 meson is measured in approximately 3 million hadronic Z decays accumulated using the ALEPH detector at LEP from 1991 to 1994. Seven different Ds− decay modes were reconstructed and combined with an opposite sign lepton as evidence of semileptonic Bs0 decays. Two hundred and eight Ds−l+ candidates satisfy selection criteria designed to ensure precise proper time reconstruction and yield a measured Bs0 lifetime of τ(Bs0) = 1.59−0.15+0.17 (stat) ±0.03 (syst) ps. Using a larger, less constrained sample of events, the product branching ratio is measured to be Br ( b → B s 0 ) · Br(B s 0 → D s − l + νX) = 0.82 ± 0.09 (stat) −0.14+0.13 (syst) %.

Correction to: Major adverse cardiovascular events in non-valvular atrial fibrillation with chronic obstructive pulmonary disease: the ARAPACIS study.

Correction to: Internal and Emergency Medicine (2018) 13:651–660 https://doi.org/10.1007/s11739-018-1835-9 In the original publication, one of the ARAPACIS collaborators Dr. “Leonardo Di Gennaro” name has been erroneously mentioned as “Leonardo De Gennaro”.

The topology dependence of charged particle multiplicities in three-jet events

A study of individual jet and whole-event charged particle multiplicities in three-jet events measured in e(+)e(-) annihilation at the Z reveals a significant topology dependence. Mean jet multiplicities are inadequately described by jet energies; interjet angles must also be specified. Quantitative tests suggest that it is necessary to use transverse-momentum-like scales to describe the data. RI ANTONELLI, ANTONELLA/C-6238-2011; Passalacqua, Luca/F-5127-2011; Murtas, Fabrizio/B-5729-2012; St.Denis, Richard/C-8997-2012; Sanchez, Federico/F-5809-2012; Forti, Francesco/H-3035-2011; Ferrante, Isidoro/F-1017-2012

Measurement of the W-pair cross section in $e^+ e^-$ collisions at 172 GeV

The e(+)e(-) --> W+W- cross section is measured in a data sample collected by ALEPH at a mean centre-of-mass energy of 172.09 GeV, corresponding to an integrated luminosity of 10.65 pb(-1). Cross sections are given for the three topologies, fully leptonic, semi-leptonic and hadronic of a W-pair decay. Under the assumption that no other decay modes are present, the W-pair cross section is measured to be 11.7 +/- 1.2(stat.) +/- 0.3(syst.) pb. The existence of the triple gauge boson vertex of the Standard Model is clearly preferred by the data. The decay branching ratio of the W boson into hadrons is measured to be B(W --> hadrons) = 67.7 +/- 3.1(stat.) +/- 0.7(syst.) %, allowing a determinati…

Comparison of Disease Clusters in Two Elderly Populations Hospitalized in 2008 and 2010

&lt;b&gt;&lt;i&gt;Background:&lt;/i&gt;&lt;/b&gt; As chronicity represents one of the major challenges in the healthcare of aging populations, the understanding of how chronic diseases distribute and co-occur in this part of the population is needed. &lt;b&gt;&lt;i&gt;Objectives:&lt;/i&gt;&lt;/b&gt; The aims of this study were to evaluate and compare patterns of diseases identified with cluster analysis in two samples of hospitalized elderly. &lt;b&gt;&lt;i&gt;Methods:&lt;/i&gt;&lt;/b&gt; Data were obtained from the multicenter ‘Registry Politerapie SIMI (REPOSI)' that included people aged 65 or older hospitalized in internal medicine and geriatric wards in Italy during 2008 and 2010. The s…

Single- and multi-photon production in e+e− collisions at a centre-of-mass energy of 183 GeV

The production of final states involving one or more energetic photons from e(+)e(-) collisions is studied in a sample of 58.5 pb(-1) of data recorded at a centre-of-mass energy of 183 GeV by the ALEPH detector at LEP. The e(+)e(-) --> v (v) over bar gamma(gamma) and e(+)e(-) --> gamma gamma(gamma) cross sections are measured. The data are in good agreement with predictions based on the Standard Model and are used to set upper limits on the cross sections for anomalous photon production in the context of two supersymmetric models and for various extensions to QED. In particular, in the context of a super-light gravitino model a cross section upper limit of 0.38 pb is placed on the process e…

A measurement of Rb using mutually exclusive tags

A measurement of R-b using five mutually exclusive hemisphere tags has been performed by ALEPH using the full LEP1 statistics. Three tags are designed to select the decay of the Z(0) to b quarks, while the remaining two select Z(0) decays to c and light quarks, and are used to measure the tagging efficiencies. The result, R-b = 0.2159 +/- 0.0009(stat) +/-0.0011(syst), is in agreement with the electroweak theory prediction of 0.2158 +/- 0.0003. (C) 1997 Published by Elsevier Science B.V. RI ANTONELLI, ANTONELLA/C-6238-2011; Passalacqua, Luca/F-5127-2011; Murtas, Fabrizio/B-5729-2012; St.Denis, Richard/C-8997-2012; Forti, Francesco/H-3035-2011; Ferrante, Isidoro/F-1017-2012

The stigma of low opioid prescription in the hospitalized multimorbid elderly in Italy.

The primary aim of this study was to evaluate the prevalence of opioid prescriptions in hospitalized geriatric patients. Other aims were to evaluate factors associated with opioid prescription, and whether or not there was consistency between the presence of pain and prescription. Opioid prescriptions were gathered from the REgistro POliterapie Societa` Italiana di Medicina Interna (REPOSI) data for the years 2008, 2010 and 2012. 1,380 in-patients, 65+ years old, were enrolled in the first registry run, 1,332 in the second and 1,340 in the third. The prevalence of opioid prescription was calculated at hospital admission and discharge. In the third run of the registry, the degree of pain was…

A measurement of the QCD colour factors and a limit on the light gluino

Using data collected from 1992 to 1995 with the ALEPH detector at LEP, a measurement of the colour factor ratios C-A/C-F and T-F/C-F and the strong coupling constant = C-F alpha(s), (M-Z)/(2 pi) has been performed by fitting theoretical predictions simultaneously to the measured differential two-jet rate and angular distributions in four-jet events. The result is found to be in excellent agreement with QCD. C-A/C-F = 2.20 +/- 0.09 (stat) +/- 0.13 (syst), T-F/C-F = 0.29 +/- 0.05 (stat) +/- 0.06 (syst). Fixing C-A/C-F and T-F/C-F to the QCD values permits a determination of alpha(s) (M-Z) and n(f), the number of active flavours. With this measurement the existence of a gluino with mass below …

Four-jet final state production in $e^+ e^-$ collisions at centre-of-mass energies ranging from 130 to 184 GeV

The four jet topology is analysed in the ALEPH data taken between November 1995 and November 1997, at centre-of-mass energies ranging from 130 to 184 GeV. While an unexpected accumulation of events with a dijet mas sum around 105 GeV/c**2 had been observed during the first run in 1995 at 130/136 GeV, corresponding to an integrated luminosity of 5.7 pb-1, no significant differences between data and standard model prediction is noticed, either in the high energy runs (81.1 pb-1 taken at centre-of-mass energies from 161 to 184 GeV) or in the 7.1 pb-1 recorded during a new short run at 130/136 GeV in 1997. We have found no other explanation for the earlier reported ``four jet anomaly'' than a s…

How, when and where from of the Abruzzo-Apulian palaeofauna.

Measurement of the transverse spin correlations in the decay Z → τ+τ-

For tau leptons produced in e(+)e(-) --> tau(+)tau(-) interactions there are, in addition to the longitudinal spin correlations, two independent transverse spin correlations associated with the transverse (within the production plane) and normal (to the production plane) polarization components. A measurement of the transverse-transverse and transverse-normal tau spin correlations in the decay Z --> tau(+)tau(-), C-TT and C-TN, is presented based on the aplanarity angle of the decay products of both tau leptons. Using 80 pb(-1) of data collected by ALEPH on the peak of the Z resonance, the results are C-TT = 1.06 +/- 0.13(stat) +/- 0.05(syst), and C-TN = 0.08 +/- 0.13(stat) +/- 0.04(syst). …