0000000000988888

AUTHOR

H J Schmitt

showing 3 related works from this author

In vitro activity of the new semi-synthetic polypeptide cilofungin (LY121019) against Aspergillus and Candida species.

1990

The in vitro activity of cilofungin (LY121019), a new semi-synthetic antifungal agent was evaluated. Potent activity was seen against Candida albicans and Candida tropicalis, with almost identical MIC and MFC results, whereas no activity was seen against any isolates of Candida parapsilosis or three Aspergillus spp. However, MICs were dependent on medium and test conditions chosen. It is concluded that cilofungin has good activity against some medically important yeasts in vitro, and that its in vitro activity depends on the method used.

Microbiology (medical)AntifungalAspergillusbiologymedicine.drug_classAntibioticsCilofunginGeneral Medicinebiology.organism_classificationPeptides CyclicIn vitroCorpus albicansSemi syntheticMicrobiologychemistry.chemical_compoundEchinocandinsInfectious DiseasesAspergilluschemistrymedicinePeptidesCandidaEuropean journal of clinical microbiologyinfectious diseases : official publication of the European Society of Clinical Microbiology
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Meningitis bei 154 Kindern einer Kinderklinik in Deutschland: Klinische und epidemiologische Aspekte

1992

In a retrospective study, the histories of the non-neonates treated for primary meningitis in the Pediatric Department of Mainz University Hospital between 1986 and 1989 were analyzed with regard to etiological, diagnostic, clinical and epidemiological criteria. In the period studied there were 37 cases of infectious meningitis (11 Neisseria meningitidis (29.7%), 7 H. influenzae (18.9%), 3 S. pneumoniae (8.1%), 16 other (43.2%)), and 117 cases of acute aseptic meningitis syndrome (12 mumps virus (10.3%), 3 Borrelia burgdorferi (7.7%), 3 FSME (2.6%), 2 herpes simplex virus, 91 other (77.8%)). Sixty-six percent of the patients were male. Of the infants with infectious meningitis, 68% were und…

Pediatricsmedicine.medical_specialtymedicine.diagnostic_testbusiness.industryLumbar punctureNeisseria meningitidisAseptic meningitisMumps virusmedicine.disease_causemedicine.diseaseInfectious disease (medical specialty)Pediatrics Perinatology and Child HealthEpidemiologymedicineEtiologybusinessMeningitisKlinische Pädiatrie
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Diarrhoe bei 1337 Kindern der Universitätsklinik Mainz: Bedeutung von Salmonellen und Rotaviren

1993

In Germany, infectious diseases cause little mortality, but they are responsible for a large proportion of morbidity. In order to obtain data about the relevance of infectious diarrhea, the charts of 1337 outpatients, hospitalized for this disorder in the time between 1986-1989 at the Children's Hospital, Johannes Gutenberg University Mainz, were analyzed. Sixty-seven percent of patients were younger than one year. An offending organism could be isolated in 42.1% of patients, with Rotaviruses being the leading cause of diarrhea (415 cases), followed by Salmonella spp. (130 cases). Rotavirus-disease was mainly seen in winter, Salmonella-disease in late summer and in autumn. Severe courses of…

Pediatricsmedicine.medical_specialtySalmonellaCross-sectional studybusiness.industryIncidence (epidemiology)medicine.disease_causeSurgeryDiarrheaEl NiñoRotavirusPediatrics Perinatology and Child HealthEpidemiologymedicinemedicine.symptombusinessFecesKlinische Pädiatrie
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