0000000000989982

AUTHOR

S Delibegovic

showing 7 related works from this author

Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery

2019

Ileus is common after elective colorectal surgery, and is associated with increased adverse events and prolonged hospital stay. The aim was to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs) for reducing ileus after surgery.A prospective multicentre cohort study was delivered by an international, student- and trainee-led collaborative group. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The primary outcome was time to gastrointestinal recovery, measured using a composite measure of bowel function and tolerance to oral intake. The impact of NSAIDs was explored using Cox regression analyses, including the results of a c…

Malerenal failureTime Factorsmedicine.medical_treatmentAdult; Aged; Anti-Inflammatory Agents Non-Steroidal; Elective Surgical Procedures; Female; Humans; Ileus; Kaplan-Meier Estimate; Male; Middle Aged; Patient Safety; Postoperative Care; Postoperative Complications; Proportional Hazards Models; Prospective Studies; Recovery of Function; Time Factors; Treatment Outcome; Colectomy; ProctectomyAnti-Inflammatory Agentscolorectal surgery; ileus; non-steroidal anti-inflammatory drugs; NSAIDSKaplan-Meier Estimate030230 surgeryTumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]0302 clinical medicinePostoperative ComplicationsProspective StudiesProspective cohort studyColectomyColorectalColectomyRISKProctectomyHazard ratioAnti-Inflammatory Agents Non-SteroidalAcute kidney injuryMiddle AgedColorectal surgeryNSAIDTreatment OutcomeElective Surgical Procedures030220 oncology & carcinogenesisFemalePatient SafetyNon-SteroidalCohort studyAdultcolorectal Surgery ileus non-steroidal anti-inflammatory drugsmedicine.medical_specialtyIleusNon‐steroidal anti‐inflammatory drugs. NSAIDs. Postoperative ileus. Colorectal surgery.ACUTE KIDNEY INJURYanti-inflammatory agents03 medical and health sciencesIleusInternal medicinemedicineHumansAdverse effectAgedProportional Hazards Modelsnon-steroidal anti-inflammatory drugs - ileus - colorectal surgeryPostoperative Carebusiness.industryRecovery of Functionmedicine.diseaseSettore MED/18 - Chirurgia Generalecolorectal cancer.Surgerycolorectal surgerybusiness
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Safety of hospital discharge before return of bowel function after elective colorectal surgery

2020

Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function.A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multiva…

operativeMalepostoperative dischargePostoperative Complications0302 clinical medicineColostomyCRITERIAProspective StudiesBowel functionColectomyIMAGINEstomaintestinesProctectomyIleostomydigestive oral and skin physiologypatient dischargecolorectal surgery hospital discharge bowel functionRECOVERYMiddle Agedadult; colostomy; elective surgical procedures; female; follow-up studies; humans; ileostomy; ileus; male; middle aged; multivariate analysis; patient discharge; patient readmission; patient safety; postoperative complications; prospective studies; recovery of function; colectomy; proctectomyPatient DischargeColorectal surgeryileus - - discharge - bowel function - elective - colorectal surgeryElective Surgical Procedures030220 oncology & carcinogenesisFemale030211 gastroenterology & hepatologyPatient SafetyCohort studysafetyAdultmedicine.medical_specialtyIleusPatient Readmissiondefecation03 medical and health sciencesIleuspostoperative complicationsmedicineHospital dischargeHumanscolorectal surgery; postoperative discharge; IMAGINE; stomacolorectal resectionColorectal resectiondefecation postoperative complications colorectal surgery intestines patient discharge patient readmission safety surgical procedures operative colorectal resection ileusbusiness.industryRecovery of FunctionOdds ratiomedicine.diseasedigestive system diseasessurgical proceduresSurgeryMultivariate AnalysisDefecationcolorectal surgerySurgerybusinessFollow-Up Studies
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Evaluating the incidence of pathological complete response in current international rectal cancer practice: the barriers to widespread safe deferral …

2018

INTRODUCTION: The mainstay of management for locally advanced rectal cancer is chemoradiotherapy followed by surgical resection. Following chemoradiotherapy, a complete response may be detected clinically and radiologically (cCR) prior to surgery or pathologically after surgery (pCR). We aim to report the overall complete pathological response (pCR) rate and the reliability of detecting a cCR by conventional pre-operative imaging.METHODS: A pre-planned analysis of the European Society of Coloproctology (ESCP) 2017 audit was performed. Patients treated by elective rectal resection were included. A pCR was defined as a ypT0 N0 EMVI negative primary tumour; a partial response represented any r…

MaleColorectal cancerdeferral of surgery; neoadjuvant therapy; pathology; radiology; rectal cancer; Rectal surgery; surgical oncology; Gastroenterology0302 clinical medicineProspective StudiesProspective cohort studyComplete responseMedical Auditintegumentary systemIncidence (epidemiology)IncidenceRemission InductionGastroenterologyMiddle AgedMagnetic Resonance ImagingPeer reviewEuropeTreatment Outcomedeferral of surgeryResponse Evaluation Criteria in Solid Tumors030220 oncology & carcinogenesisPreoperative Period030211 gastroenterology & hepatologyFemaleAdultmedicine.medical_specialtyRectal surgeryNO03 medical and health sciencessurgical oncologymedicineHumansneoadjuvant therapyIntensive care medicineDeferralrectal cancerPathologicalResponse Evaluation Criteria in Solid TumorsAgedNeoplasm Stagingta3126business.industryRectal NeoplasmsReproducibility of ResultsChemoradiotherapy Adjuvantmedicine.diseaseradiologyRectal Neoplasms/diagnostic imagingpathologyNeoplasm Staging/methodsbusiness
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An international multicentre prospective audit of elective rectal cancer surgery; operative approach versus outcome, including transanal total mesore…

2018

Introduction: Transanal total mesorectal excision (TaTME) has rapidly emerged as a novel approach for rectal cancer surgery. Safety profiles are still emerging and more comparative data is urgently needed. This study aimed to compare indications and short-term outcomes of TaTME, open, laparoscopic, and robotic TME internationally. Methods: A pre-planned analysis of the European Society of Coloproctology (ESCP) 2017 audit was performed. Patients undergoing elective total mesorectal excision (TME) for malignancy between 1 January 2017 and 15 March 2017 by any operative approach were included. The primary outcome measure was anastomotic leak. Results: Of 2579 included patients, 76.2% (1966/257…

MaleLaparoscopic surgerymedicine.medical_specialtyColorectal cancermedicine.medical_treatmentOperative TimeAnastomosisMalignancyrectal cancer ; laparoscopic surgery ; TME ; transanal TME ; TaTME ; robotic surgery ; randomized clinical-trial ; short-term outcomes ; laparoscopic-assisted resection ; pathological outcomes ; anastomotic leakage ; initial-experience ; riskNO03 medical and health sciencesPostoperative Complications0302 clinical medicineRobotic Surgical Proceduresrobotic surgerytransanal TMEHumansMedicineRobotic surgeryProspective Studieslaparoscopic surgery; Rectal cancer; robotic surgery; TaTME; TME; transanal TME; GastroenterologyRectal cancerAgedTransanal Endoscopic Surgeryta3126Medical AuditUnivariate analysisProctectomyRectal Neoplasmsbusiness.industryRectumGastroenterologyTMEMargins of ExcisionMiddle Agedmedicine.diseaseTotal mesorectal excisionTaTMElaparoscopic surgerySurgeryTreatment OutcomeElective Surgical Procedures030220 oncology & carcinogenesisRectal cancer surgeryFemaleLaparoscopy030211 gastroenterology & hepatologybusiness
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Global validation of the WSES Sepsis Severity Score for patients with complicated intra-abdominal infections : a prospective multicentre study (WISS …

2015

BACKGROUND: To validate a new practical Sepsis Severity Score for patients with complicated intra-abdominal infections (cIAIs) including the clinical conditions at the admission (severe sepsis/septic shock), the origin of the cIAIs, the delay in source control, the setting of acquisition and any risk factors such as age and immunosuppression. ----- METHODS: The WISS study (WSES cIAIs Score Study) is a multicenter observational study underwent in 132 medical institutions worldwide during a four-month study period (October 2014-February 2015). Four thousand five hundred thirty-three patients with a mean age of 51.2 years (range 18-99) were enrolled in the WISS study. ----- RESULTS: Univariate…

medicine.medical_specialtyInfections; Intra-abdominal; Sepsis; Septic shock:Ciências da Saúde [Ciências Médicas]Infections; Intra-abdominal; Sepsis; Septic shock; Surgery; Emergency MedicineCiências Médicas::Ciências da SaúdeSepsimedicine.medical_treatment/macromolecular substances030230 surgeryGUIDELINESInfectionsLikelihood ratios in diagnostic testingSepsisPERITONITIS03 medical and health sciencesPROGNOSTIC-FACTORS0302 clinical medicineInternal medicineSepsisSeptic shockMedicine and Health SciencesMANAGEMENTmedicineIntra-abdominalIntra-abdominal SepsisUnivariate analysisScience & TechnologyCOLONIC PERFORATIONReceiver operating characteristicbusiness.industrySeptic shockAbdominal InfectionImmunosuppression3126 Surgery anesthesiology intensive care radiologymedicine.disease3. Good healthSurgery030220 oncology & carcinogenesisInfections Intra-abdominal Sepsis; Septic shockEmergency MedicineSurgeryObservational studyInfectionbusinessSYSTEMResearch Article
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Safety of primary anastomosis following emergency left sided colorectal resection: an international, multi-centre prospective audit

2018

Introduction: Some evidence suggests that primary anastomosis following left sided colorectal resection in the emergency setting may be safe in selected patients, and confer favourable outcomes to permanent enterostomy. The aim of this study was to compare the major postoperative complication rate in patients undergoing end stoma vs primary anastomosis following emergency left sided colorectal resection. Methods: A pre-planned analysis of the European Society of Coloproctology 2017 audit. Adult patients (> 16 years) who underwent emergency (unplanned, within 24 h of hospital admission) left sided colonic or rectal resection were included. The primary endpoint was the 30-day major complic…

MaleMedical auditTreatment outcomeanastomotic leak030230 surgery0302 clinical medicinePostoperative ComplicationsProspective StudiesMulti centreemergency surgeryProspective cohort studyColectomyMedical AuditProctectomyProctectomy/adverse effectsProspective auditPrimary anastomosisAnastomosis SurgicalGastroenterologyMiddle Agedsurgical complicationsEuropeTreatment Outcomecolon canceranastomotic leak; colon cancer; emergency surgery; gastrointestinal surgery; rectal cancer; Surgery; surgical complications; surgical outcomes; Gastroenterology030220 oncology & carcinogenesisPostoperative Complications/etiologyFemaleColectomy/adverse effectsEmergency Treatment/adverse effectsAdultmedicine.medical_specialtyAdolescentsurgical outcomesurgical outcomesLeft sidedNO03 medical and health sciencesYoung Adultsurgical complicationmedicineHumansgastrointestinal surgeryrectal cancerEmergency TreatmentColorectal resectionAgedta3126Anastomosis Surgical/methodsbusiness.industryGeneral surgerySurgical StomasSurgical Stomas/statistics & numerical dataSettore MED/18 - Chirurgia GeneraleMultivariate AnalysisSurgerybusiness
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Prospective Observational Study on acute Appendicitis Worldwide (POSAW)

2018

Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departments.

Male:Medicina Básica [Ciências Médicas]Computed tomography030230 surgery0302 clinical medicineAntibioticsDiagnosisAppendicitiProspective StudiesLaparoscopyProspective cohort studyTomographymedicine.diagnostic_testAcute appendicitis; Antibiotics; Diagnosis; Management; Surgery; Surgery; Emergency MedicineAcute appendicitis; Antibiotics; Diagnosis; Management; Surgery; Acute Disease; Adult; Appendectomy; Appendicitis; Chi-Square Distribution; Female; Hospitalization; Humans; Laparoscopy; Length of Stay; Logistic Models; Male; Prospective Studies; Tomography X-Ray Computed; Treatment OutcomeMortality ratelcsh:Medical emergencies. Critical care. Intensive care. First aidApendicite3. Good healthX-Ray ComputedManagementHospitalizationTreatment Outcome030220 oncology & carcinogenesisCiências Médicas::Medicina BásicaAcute appendicitisAcute DiseaseEmergency MedicineFemaleAcute appendicitis; Antibiotics; Diagnosis; Management; Surgery; Acute Disease; Adult; Appendectomy; Appendicitis; Chi-Square Distribution; Female; Hospitalization; Humans; Laparoscopy; Length of Stay; Logistic Models; Male; Prospective Studies; Tomography X-Ray Computed; Treatment Outcome; Surgery; Emergency MedicineDiagnosiHumanResearch ArticleAdultmedicine.medical_specialtyLogistic Modellcsh:SurgeryNO03 medical and health sciencesmedicineAppendectomyHumansAcute appendicitisChi-Square Distributionbusiness.industryGeneral surgeryAntibioticAcute appendicitis; Antibiotics; Diagnosis; Management; Surgerylcsh:RD1-811lcsh:RC86-88.9Length of Staymedicine.diseaseAppendicitisAppendicitisProspective StudieLogistic ModelsObservational studyLaparoscopySurgeryAcute appendicitibusinessTomography X-Ray ComputedChi-squared distributionWorld Journal of Emergency Surgery
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