0000000001092527

AUTHOR

Aline Laubriet

showing 2 related works from this author

Upregulation of the netrin receptor (DCC) gene during activation of b lymphocytes and modulation by interleukins.

2001

The DCC (deleted in colon cancer) gene has a brain restricted high expression pattern. It encodes a transmembrane protein of the immunoglobulin superfamily identified as the netrin-1 receptor. It might be a member of the so called "brain-lymphoid" molecules, which control key cell surface events. To test this hypothesis we have assessed the DCC mRNA level in human normal and malignant myeloid and lymphoid cells. A high mRNA content has been observed only in mature B cells at the secreting or presecreting stage. Expression of DCC was also assessed in the anti-CD40 model of immunopoiesis. Activation of purified tonsillar B cells by anti-CD 40 antibody strongly increased the DCC mRNA level and…

AdultDeleted in Colorectal CancerTranscription GeneticT-LymphocytesPalatine TonsilBiophysicsReceptors Cell SurfaceBiologyLymphocyte ActivationBiochemistryCell LineNetrin Receptor DCCDownregulation and upregulationNetrinmedicineTumor Cells CulturedHumansRNA MessengerReceptorMolecular BiologyB cellB-LymphocytesReverse Transcriptase Polymerase Chain ReactionInterleukinsTumor Suppressor ProteinsfungiBrainCell BiologyDCC ReceptorMolecular biologyInterleukin-10Up-Regulationmedicine.anatomical_structureGenes DCCCell cultureImmunoglobulin superfamilyInterleukin-2Netrin ReceptorsCell Adhesion MoleculesImmunologic MemoryMuromonab-CD3Biochemical and biophysical research communications
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Comparison of two techniques (in vivo and ex-vivo) for evaluating the elastic properties of the ascending aorta: Prospective cohort study.

2021

Introduction Aneurysms of the ascending aorta (AA) correspond to a dilatation of the ascending aorta that progressively evolves over several years. The main complication of aneurysms of the ascending aorta is type A aortic dissection, which is associated with very high rates of morbidity and mortality. Prophylactic ascending aorta replacement guidelines are currently based on maximal AA diameter. However, this criterion is imperfect. Stretching tests on the aorta carried out ex-vivo make it possible to determine the elastic properties of healthy and aneurysmal aortic fragments (tension test, resistance before rupture). For several years now, cardiac magnetic resonance imaging (MRI) has pro…

Magnetic Resonance SpectroscopyVascular MedicineDiagnostic RadiologyStiffnessBreath HoldingAortic aneurysmMedicine and Health SciencesBiomechanicsProspective StudiesPulse wave velocityAortaAortic dissectionMultidisciplinarymedicine.diagnostic_testCardiac cycleRadiology and ImagingQRArteriesMagnetic Resonance ImagingAortic AneurysmBiomechanical PhenomenaDescending aortaPhysical Sciencescardiovascular systemMedicineAnatomyAneurysmsMaterials scienceImaging TechniquesScienceMaterials ScienceMaterial PropertiesMagnetic Resonance Imaging CineSurgical and Invasive Medical ProceduresPulse Wave AnalysisResearch and Analysis MethodsDiagnostic MedicineCardiac magnetic resonance imagingRegistered Report Protocolmedicine.arteryAscending aortamedicineMechanical PropertiesHumansVascular DiseasesAortabusiness.industryBiology and Life Sciencesmedicine.diseaseElasticityCardiovascular AnatomyBlood VesselsNuclear medicinebusinessPLoS ONE
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