0000000001095884

AUTHOR

G. Di Paola

showing 6 related works from this author

Cachexia induces head and neck changes in locally advanced oropharyngeal carcinoma during definitive cisplatin and image-guided volumetric-modulated …

2015

Cancer cachexia is a syndrome characterized by weight loss (WL) and sarcopenia. Aim of the study was to assess the impact of cachexia on head and neck changes during definitive cisplatin and image-guided volumetric-modulated arc radiation therapy in a series of locally advanced oropharyngeal cancer.Volume variations of sternocleidomastoid muscle (SCM) were considered as surrogate of muscle changes related to sarcopenia. Two head and neck diameters, encompassing the cranial limits of II and III nodal levels (defined as 'head diameter' and 'neck diameter', respectively), were measured. All parameters were defined retrospectively by means of on-board cone beam computed tomography images at 1-8…

AdultMaleOncologymedicine.medical_specialtyCachexiamedicine.medical_treatmentLocally advancedMedicine (miscellaneous)030218 nuclear medicine & medical imagingCachexia03 medical and health sciences0302 clinical medicineInternal medicineWeight LossCarcinomamedicineHumansskin and connective tissue diseasesAgedCisplatinNutrition and DieteticsArc (protein)business.industryMiddle Agedmedicine.diseaseRadiation therapyOropharyngeal NeoplasmsOropharyngeal Carcinoma030220 oncology & carcinogenesisSarcopeniaFemaleRadiotherapy Intensity-Modulatedsense organsRadiologyCisplatinbusinessHeadNeckmedicine.drugEuropean Journal of Clinical Nutrition
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Dose–volume-related dysphagia after constrictor muscles definition in head and neck cancer intensity-modulated radiation treatment

2014

Dysphagia remains a side effect influencing the quality of life of patients with head and neck cancer (HNC) after radiotherapy. We evaluated the relationship between planned dose involvement and acute and late dysphagia in patients with HNC treated with intensity-modulated radiation therapy (IMRT), after a recontouring of constrictor muscles (PCs) and the cricopharyngeal muscle (CM).Between December 2011 and December 2013, 56 patients with histologically proven HNC were treated with IMRT or volumetric-modulated arc therapy. The PCs and CM were recontoured. Correlations between acute and late toxicity and dosimetric parameters were evaluated. End points were analysed using univariate logisti…

Malemedicine.medical_specialtySide effectmedicine.medical_treatmentYoung AdultPlanned DoseSwallowingNuclear Medicine and ImagingIntensity-Modulated80 and overotorhinolaryngologic diseasesHumansMedicineRadiology Nuclear Medicine and imagingTomographyAgedRetrospective StudiesAged 80 and overFull PaperAged; Aged 80 and over; Deglutition; Deglutition Disorders; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Laryngeal Muscles; Male; Middle Aged; Quality of Life; Radiotherapy Dosage; Radiotherapy Intensity-Modulated; Retrospective Studies; Tomography X-Ray Computed; Young Adult; Radiology Nuclear Medicine and ImagingRadiotherapybusiness.industryHead and neck cancerRadiotherapy DosageRetrospective cohort studyGeneral MedicineMiddle Agedmedicine.diseaseDysphagiaAcute toxicityDeglutitionX-Ray ComputedSurgeryRadiation therapyHead and Neck NeoplasmsQuality of LifeFemaleRadiotherapy Intensity-ModulatedRadiologyLaryngeal Musclesmedicine.symptomTomography X-Ray ComputedDeglutition DisordersRadiologybusinessFollow-Up StudiesThe British Journal of Radiology
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Intensity modulated radiation therapy with simultaneous integrated boost in early breast cancer irradiation. Report of feasibility and preliminary to…

2015

To investigate the feasibility and tolerance in the use of adjuvant intensity modulated radiation therapy (IMRT) and simultaneous integrated boost in patients with a diagnosis of breast cancer after breast-conserving surgery.Between September 2011 to February 2013, 112 women with a diagnosis of early breast cancer (T1-2, N0-1, M0) were treated with IMRT and simultaneous integrated boost after breast-conserving surgery in our institution. A dose of 50Gy in 25 fractions was prescribed to the whole breast and an additional dose of radiation was prescribed on the tumour bed. A dose prescription of 60Gy in 25 fractions to the tumour bed was used in patients with negative margins after surgery, w…

Oncologymedicine.medical_treatmentSegmentalMastectomy SegmentalSeverity of Illness IndexBreast cancerNuclear Medicine and ImagingDuctalIntensity-Modulated80 and overBreastMastectomyAdjuvantEarly breast cancerAged 80 and overCarcinoma Ductal BreastSIBRadiotherapy DosageMiddle AgedOncologyBreast cancer; IMRT; SIB; Toxicity; Adult; Aged; Aged 80 and over; Breast Neoplasms; Carcinoma Ductal Breast; Carcinoma Lobular; Esthetics; Feasibility Studies; Female; Follow-Up Studies; Humans; Mastectomy Segmental; Middle Aged; Radiodermatitis; Radiotherapy Dosage; Radiotherapy Adjuvant; Severity of Illness Index; Radiotherapy Intensity-Modulated; Oncology; Radiology Nuclear Medicine and ImagingToxicityFemaleRadiologyRadiodermatitisRadiologyAdjuvantSimultaneous integrated boostAdultmedicine.medical_specialtyEstheticsBreast NeoplasmsLobularBreast cancerInternal medicineSeverity of illnessmedicineHumansRadiology Nuclear Medicine and imagingIMRTAgedToxicityRadiotherapybusiness.industryCarcinomaIntensity-modulated radiation therapymedicine.diseaseAcute toxicityBreast cancer; IMRT; SIB; Toxicity; Oncology; Radiology Nuclear Medicine and ImagingCarcinoma LobularFeasibility StudiesRadiotherapy AdjuvantRadiotherapy Intensity-ModulatedbusinessFollow-Up Studies
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Lipids, Lipoproteins and Apolipoproteins A<sub>I</sub> A<sub>II</sub>, B, C<sub>II</sub>, C<sub>III</sub…

1991

In this study lipid and apolipoprotein patterns were investigated at birth and compared with those of adults. In cord sera, cholesterol, triglycerides, low-density lipoprotein (LDL) cholesterol and high-density lipoprotein (HDL) cholesterol were 38.2, 46.2, 50.5, and 31.9%, respectively, of adult values. Apolipoprotein A<sub>II</sub>, B and C<sub>III</sub> were 48.6, 30.6 and 44.5% of adult values, while apo A<sub>I</sub>, apo C<sub>II</sub> and apo E showed values approaching those of adults (63.4, 73.3 and 89.7%, respectively). Also cholesterol/HDL cholesterol and LDL cholesterol/HDL cholesterol ratios were lower in newborns. In cord sera, l…

Apolipoprotein ELdl cholesterolmedicine.medical_specialtyApolipoprotein BbiologyCholesterolLipid metabolismMetabolismPositive correlationchemistry.chemical_compoundEndocrinologychemistryInternal medicinePediatrics Perinatology and Child Healthmedicinebiology.proteinlipids (amino acids peptides and proteins)Developmental BiologyLipoproteinNeonatology
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Laparotomic vs laparoscopic ovariectomy: comparing the two methods. The ovariectomy in the bitch in laparoscopic era

2015

BACKGROUND: The aim of the present work is to evaluate the effectiveness of the use of ultrasound scalpel during laparoscopic ovariectomy in the bitch. METHODS: Two groups of 10 subjects each, of different races and ages, were compared. In the first group, ovariectomy was performed laparoscopically, using harmonic scalpel to remove ovary. In the second group surgery was performed by means of classical laparotomy. RESULTS: Pre-operative time was similar in both groups. Total operative time, from incision to skin suture, showed significant difference between the two groups, being laparoscopy faster than laparotomy. Partial operative time for bilateral oophorectomy resulted lower using open te…

LaparotomySettore MED/18 - Chirurgia GeneraleDogsOvariectomySettore VET/09 - Clinica Chirurgica VeterinariaOperative TimeSettore VET/10 - Clinica Ostetrica E Ginecologia VeterinariaAnimalsFemaleLaparoscopySettore MED/40 - Ginecologia E Ostetriciaoophorectomy laparotomy laparoscopy harmonic scalpel
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Transient Neonatal Hypercholesterolemia

1993

In order to obtain new information about the relationship between transient neonatal hypercholesterolemia and adrenal gland function, we have studied 39 healthy babies found hypercholesterolemic at birth and 39 healthy controls with normal cholesterol levels. The results of this study have shown that levels of dehydroepiandrosterone sulfate in cord blood were not significantly different in the hypercholesterolemic subjects compared with normolipidemic controls (1.4 +/- 0.5 micrograms/dl vs 1.3 +/- 0.5 mu/dl). Moreover correlations between this hormone and levels of total and LDL-cholesterol were not only not statistically significant but even positive (respectively r = +0.207 and +0.195). T…

medicine.medical_specialtyAdrenal glandbusiness.industryCholesterolEndocrinology Diabetes and Metabolismmedicine.medical_treatmentBiochemistry (medical)Clinical BiochemistryGeneral MedicineBiochemistryPathophysiologychemistry.chemical_compoundSteroid hormoneEndocrinologymedicine.anatomical_structureDehydroepiandrosterone sulfateEndocrinologychemistryInternal medicineCord bloodmedicineNormal cholesterolbusinessHormoneHormone and Metabolic Research
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