0000000001142153
AUTHOR
Tiziana Fornari
Solubility of solid carnosic acid in supercritical CO2 with ethanol as a co-solvent
Abstract The present study is devoted to the experimental measurement and thermodynamic modeling of solid carnosic acid solubility in supercritical CO 2 + ethanol as a co-solvent. Measurements were carried out at temperatures in the range of 313.15 and 333.15 K, pressures ranging from 280 to 400 bar, and at different content of the modifier ethanol (from 0.7 to 10%). The Group Contribution Associating Equation of State (GCA-EoS) [H.P. Gros, S.B. Bottini, E.A. Brignole, High pressure phase equilibrium modeling of mixtures containing associating compounds and gases, Fluid Phase Equilibria 139 (1997) 75–87] was applied in this work to represent the experimental solubility data obtained. Due t…
Solubility of quercetin in supercritical CO2 + ethanol as a modifier: measurements and thermodynamic modelling
Abstract Grape seeds extracts have shown a broad range of pharmacological activities including, among others, antiulcer and antioxidant properties, which are mainly attributed to the phenolic compounds present. To date, the most abundant phenolic compounds isolated from grape seeds are catechins and their derivatives, e.g. quercetin. The present study is devoted to the experimental measurement and thermodynamic modelling of the solubility of quercetin in supercritical CO 2 + ethanol as a co-solvent. The solubility of quercetin was measured at 313.15 K, pressures ranging from 80 to 120 bar, and at different content of the modifier ethanol—from 5 to 30%. Two types of thermodynamic models were…