0000000001152936
AUTHOR
H. Setyadharma
showing 2 related works from this author
An economical hemoperfusion system to determine in vitro clearances of various poisons with different adsorbents.
1980
An economical hemoperfusion system for clearance studies in vitro was developped. It was ascertained, that hemoperfusion using columns which contain 13 g of adsorbent and perfused at a blood flow rate of 1.25 ml/min results in the same relative clearances as when using clinical sized columns containing 300–355 g of the absorbent and run at 100 ml/min. The adsorption kinetics of toxicologically important drugs and pesticides are given as examples. To date 27 substances were tested systematically. The investigation has shown, that no adsorbent is without exception the best one, but the efficacy can vary from substance to substance.
Successful treatment of paraquat poisoning: activated charcoal per os and "continuous hemoperfusion".
1982
AbstractIngestion of paraquat results in an extremely dangerous poisoning. The first aim is to clear the gastrointestinal tract by inducing emesis and performing gastric/gut lavage; as much activated charcoal as possible should be administered per os and as quickly as possible. The best measure to eliminate paraquat from blood and tissue is hemoperfusion with coated activated charcoal; it has to be performed in the sense of “continuous hemoperfusion” about 8 h/d over a period of 2–3 weeks. These measures give a chance to lower the lethality of paraquat poisoning.