6533b873fe1ef96bd12d5745
RESEARCH PRODUCT
Successful treatment of paraquat poisoning: activated charcoal per os and "continuous hemoperfusion".
L. S. WeilemannT. ThonC. A. BaldamusJ. MajdandzicK. E. BonzelJ. LohmannH. J. ReineckeS. OkonekH. Setyadharmasubject
inorganic chemicalsMaleParaquatTime FactorsAdolescentHealth Toxicology and Mutagenesismedicine.medical_treatmentMagnesium CompoundsToxicologychemistry.chemical_compoundParaquatMedicineAnimalsHumansAluminum CompoundsKaolinTherapeutic IrrigationGastrointestinal tractbusiness.industrySilicatesRats Inbred StrainsHemoperfusionPARAQUAT POISONINGRatsHemoperfusionchemistryActivated charcoalAnesthesiaCharcoalBentoniteAluminum SilicatesFemaleAdsorptionbusinessdescription
AbstractIngestion of paraquat results in an extremely dangerous poisoning. The first aim is to clear the gastrointestinal tract by inducing emesis and performing gastric/gut lavage; as much activated charcoal as possible should be administered per os and as quickly as possible. The best measure to eliminate paraquat from blood and tissue is hemoperfusion with coated activated charcoal; it has to be performed in the sense of “continuous hemoperfusion” about 8 h/d over a period of 2–3 weeks. These measures give a chance to lower the lethality of paraquat poisoning.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1982-10-01 | Journal of toxicology. Clinical toxicology |