0000000001216720

AUTHOR

Rossella Di Falco

showing 1 related works from this author

Improvement of osteogenic differentiation of human mesenchymal stem cells on composite poly l-lactic acid/nano-hydroxyapatite scaffolds for bone defe…

2020

Tissue engineering offers new approaches to repair bone defects, which cannot be repaired physiologically, developing scaffolds that mimic bone tissue architecture. Furthermore, biomechanical stimulation induced by bioreactor, provides biomechanical cues that regulate a wide range of cellular events especially required for cellular differentiation and function. The improvement of human mesenchymal stem cells (hMSCs) colonization in poly-L-lactic-acid (PLLA)/nano- hydroxyapatite (nHA) composite scaffold was evaluated in terms of cell proliferation (dsDNA content), bone differen- tiation (gene expression and protein synthesis) and ultrastructural analysis by comparing static (s3D) and dynamic…

0106 biological sciences0301 basic medicine3D cultureScaffoldCellular differentiationBioreactorBioengineeringBone tissue01 natural sciencesApplied Microbiology and BiotechnologyBone and BonesCell Line03 medical and health sciencesBioreactorsTissue engineeringPolylactic Acid-Polyglycolic Acid CopolymerPoly-L-lactic-acid/nano-hydroxyapatiteOsteogenesis010608 biotechnologyOsteogenic differentiation w/o growth factorsmedicineHumansBone regenerationCell ProliferationComposite scaffoldSettore ING-IND/24 - Principi Di Ingegneria ChimicaTissue EngineeringTissue ScaffoldsChemistryMesenchymal stem cell3D culture; Bioreactor; Composite scaffold; Osteogenic differentiation w/o growth factors; Poly-L-lactic-acid/nano-hydroxyapatite; Bioreactors; Bone and Bones; Cell Differentiation; Cell Line; Cell Proliferation; Durapatite; Humans; Mesenchymal Stem Cells; Osteogenesis; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Engineering; Tissue ScaffoldsSettore ING-IND/34 - Bioingegneria IndustrialeCell DifferentiationMesenchymal Stem CellsCell biologyRUNX2030104 developmental biologymedicine.anatomical_structureDurapatiteCell cultureBiotechnologyJournal of bioscience and bioengineering
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