0000000001227510

AUTHOR

B Smith

showing 8 related works from this author

Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery

2019

Ileus is common after elective colorectal surgery, and is associated with increased adverse events and prolonged hospital stay. The aim was to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs) for reducing ileus after surgery.A prospective multicentre cohort study was delivered by an international, student- and trainee-led collaborative group. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The primary outcome was time to gastrointestinal recovery, measured using a composite measure of bowel function and tolerance to oral intake. The impact of NSAIDs was explored using Cox regression analyses, including the results of a c…

Malerenal failureTime Factorsmedicine.medical_treatmentAdult; Aged; Anti-Inflammatory Agents Non-Steroidal; Elective Surgical Procedures; Female; Humans; Ileus; Kaplan-Meier Estimate; Male; Middle Aged; Patient Safety; Postoperative Care; Postoperative Complications; Proportional Hazards Models; Prospective Studies; Recovery of Function; Time Factors; Treatment Outcome; Colectomy; ProctectomyAnti-Inflammatory Agentscolorectal surgery; ileus; non-steroidal anti-inflammatory drugs; NSAIDSKaplan-Meier Estimate030230 surgeryTumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]0302 clinical medicinePostoperative ComplicationsProspective StudiesProspective cohort studyColectomyColorectalColectomyRISKProctectomyHazard ratioAnti-Inflammatory Agents Non-SteroidalAcute kidney injuryMiddle AgedColorectal surgeryNSAIDTreatment OutcomeElective Surgical Procedures030220 oncology & carcinogenesisFemalePatient SafetyNon-SteroidalCohort studyAdultcolorectal Surgery ileus non-steroidal anti-inflammatory drugsmedicine.medical_specialtyIleusNon‐steroidal anti‐inflammatory drugs. NSAIDs. Postoperative ileus. Colorectal surgery.ACUTE KIDNEY INJURYanti-inflammatory agents03 medical and health sciencesIleusInternal medicinemedicineHumansAdverse effectAgedProportional Hazards Modelsnon-steroidal anti-inflammatory drugs - ileus - colorectal surgeryPostoperative Carebusiness.industryRecovery of Functionmedicine.diseaseSettore MED/18 - Chirurgia Generalecolorectal cancer.Surgerycolorectal surgerybusiness
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Search for High-energy Neutrinos from Gravitational Wave Event GW151226 and Candidate LVT151012 with ANTARES and IceCube

2017

[EN] The Advanced LIGO observatories detected gravitational waves from two binary black hole mergers during their first observation run (O1). We present a high-energy neutrino follow-up search for the second gravitational wave event, GW151226, as well as for gravitational wave candidate LVT151012. We find two and four neutrino candidates detected by IceCube, and one and zero detected by ANTARES, within +/- 500 s around the respective gravitational wave signals, consistent with the expected background rate. None of these neutrino candidates are found to be directionally coincident with GW151226 or LVT151012. We use nondetection to constrain isotropic-equivalent high-energy neutrino emission …

POINT-LIKEGravitational-wave observatoryPhysics and Astronomy (miscellaneous)[ PHYS.ASTR ] Physics [physics]/Astrophysics [astro-ph]AstronomyELECTROMAGNETIC COUNTERPARTSastro-ph.HE; astro-ph.HEAstrophysics01 natural sciences7. Clean energylocalizationIceCubeBinary black holeLIGO010303 astronomy & astrophysicsTelescopeGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)QCPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)astro-ph.HEFollow-upData-acquisition systemobservatoryNeutrino detectorElectromagnetic counterpartsSIMULATIONBlack-hole mergersLigoGamma-ray burstsNeutrinoAstrophysics - High Energy Astrophysical PhenomenaHost galaxiesSimulationGravitational waveBLACK-HOLE MERGERSAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesDATA-ACQUISITION SYSTEMGravitational wavesneutrino: productionGeneral Relativity and Quantum CosmologyBinary black holeOnes gravitacionalsLiGO Observatory0103 physical sciencesNeutrinoGW151226ddc:530NeutrinsNeutrinos010306 general physicsPoint-likeANTARESCosmologiaGravitational wavebackgroundgravitational radiationAstronomy530 PhysikLIGONeutron starGravitational Waves Neutrinos Antares IceCube LIGOAntaresPhysics and Astronomyblack hole: binary13. Climate action:Física::Astronomia i astrofísica [Àrees temàtiques de la UPC]FISICA APLICADAAstronomiaDewey Decimal Classification::500 | Naturwissenschaften::530 | Physik[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]FOLLOW-UPPhysical Review D. Particles and Fields
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Safety of hospital discharge before return of bowel function after elective colorectal surgery

2020

Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function.A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multiva…

operativeMalepostoperative dischargePostoperative Complications0302 clinical medicineColostomyCRITERIAProspective StudiesBowel functionColectomyIMAGINEstomaintestinesProctectomyIleostomydigestive oral and skin physiologypatient dischargecolorectal surgery hospital discharge bowel functionRECOVERYMiddle Agedadult; colostomy; elective surgical procedures; female; follow-up studies; humans; ileostomy; ileus; male; middle aged; multivariate analysis; patient discharge; patient readmission; patient safety; postoperative complications; prospective studies; recovery of function; colectomy; proctectomyPatient DischargeColorectal surgeryileus - - discharge - bowel function - elective - colorectal surgeryElective Surgical Procedures030220 oncology & carcinogenesisFemale030211 gastroenterology & hepatologyPatient SafetyCohort studysafetyAdultmedicine.medical_specialtyIleusPatient Readmissiondefecation03 medical and health sciencesIleuspostoperative complicationsmedicineHospital dischargeHumanscolorectal surgery; postoperative discharge; IMAGINE; stomacolorectal resectionColorectal resectiondefecation postoperative complications colorectal surgery intestines patient discharge patient readmission safety surgical procedures operative colorectal resection ileusbusiness.industryRecovery of FunctionOdds ratiomedicine.diseasedigestive system diseasessurgical proceduresSurgeryMultivariate AnalysisDefecationcolorectal surgerySurgerybusinessFollow-Up Studies
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Properties of the Binary Neutron Star Merger GW170817

2019

On August 17, 2017, the Advanced LIGO and Advanced Virgo gravitational-wave detectors observed a low-mass compact binary inspiral. The initial sky localization of the source of the gravitational-wave signal, GW170817, allowed electromagnetic observatories to identify NGC 4993 as the host galaxy. In this work, we improve initial estimates of the binary's properties, including component masses, spins, and tidal parameters, using the known source location, improved modeling, and recalibrated Virgo data. We extend the range of gravitational-wave frequencies considered down to 23 Hz, compared to 30 Hz in the initial analysis. We also compare results inferred using several signal models, which ar…

AstrofísicaGravitacióneutron star: binaryAstronomyGeneral Physics and AstronomyBinary numberAstrophysicsELECTROMAGNETIC COUNTERPARTspin01 natural sciencesGeneral Relativity and Quantum CosmologyGRAVITATIONAL-WAVESlocalization010305 fluids & plasmasGravitational wave detectorsEQUATIONenergy: densityLIGOGEO600QCastro-ph.HESettore FIS/01PhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)GAMMA-RAY BURSTSSettore FIS/05PhysicsEquations of stateGravitational effectsGravitational-wave signalsDeformability parameterAmplitudePhysical SciencesPhysical effectsINSPIRALING COMPACT BINARIES[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc]Spectral energy densityAstrophysics - High Energy Astrophysical PhenomenaPARAMETER-ESTIMATIONBinary neutron starsdata analysis methodgr-qcQC1-999Physics MultidisciplinaryFOS: Physical sciencesGeneral Relativity and Quantum Cosmology (gr-qc)Astrophysics::Cosmology and Extragalactic AstrophysicsGravity wavesBayesianGravimeterselectromagnetic field: productionPhysics and Astronomy (all)galaxy: binary0103 physical sciencesddc:530SDG 7 - Affordable and Clean Energy010306 general physicsgravitational radiation: frequencySTFCAstrophysics::Galaxy Astrophysicsequation of stateLIGHT CURVESEquation of stateScience & Technology/dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energySpinsgravitational radiationRCUKSpectral densityKILONOVATRANSIENTSbinary: compactStarsGEO600GalaxyLIGOgravitational radiation detectorNeutron starVIRGOPhysics and Astronomygravitational radiation: emissionRADIATIONBayesian AnalysisDewey Decimal Classification::500 | Naturwissenschaften::530 | Physik[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
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Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study

2021

ObjectivesStudies have demonstrated high rates of mortality in people with proximal femoral fracture and SARS-CoV-2, but there is limited published data on the factors that influence mortality for clinicians to make informed treatment decisions. This study aims to report the 30-day mortality associated with perioperative infection of patients undergoing surgery for proximal femoral fractures and to examine the factors that influence mortality in a multivariate analysis.SettingProspective, international, multicentre, observational cohort study.ParticipantsPatients undergoing any operation for a proximal femoral fracture from 1 February to 30 April 2020 and with perioperative SARS-CoV-2 infec…

Malemedicine.medical_specialty2474Multivariate analysisMORTALITY-RATEShipSURGERYSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MULTICENTERCOVIDSurg Collaborative1117 Public Health and Health ServicesCohort StudiesMedicine General & InternalInternal medicineGeneral & Internal MedicinemedicineDementiaHumans1506Prospective StudiesAged 80 and overCOMPLICATIONSScience & TechnologyHIP-FRACTURESbusiness.industryHip FracturesSARS-CoV-2RCOVID-191103 Clinical SciencesGeneral MedicineFemoral fracturePerioperativemedicine.diseaseHeart failuretrauma managementMedicineSurgery1737businessLife Sciences & BiomedicineFemoral FracturesKidney diseaseCohort study1199 Other Medical and Health SciencesBMJ Open
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Measurement of the intrinsic electron neutrino component in the T2K neutrino beam with the ND280 detector

2014

The T2K experiment has reported the first observation of the appearance of electron neutrinos in a muon neutrino beam. The main and irreducible background to the appearance signal comes from the presence in the neutrino beam of a small intrinsic component of electron neutrinos originating from muon and kaon decays. In T2K, this component is expected to represent 1.2% of the total neutrino flux. A measurement of this component using the near detector (ND280), located 280 m from the target, is presented. The charged current interactions of electron neutrinos are selected by combining the particle identification capabilities of both the time projection chambers and electromagnetic calorimeters…

Nuclear and High Energy PhysicsParticle physicsPhysics::Instrumentation and DetectorsSolar neutrinoAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciences01 natural sciences7. Clean energyHigh Energy Physics - ExperimentNuclear physicsHigh Energy Physics - Experiment (hep-ex)0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]010306 general physicsNeutrino oscillationPhysics010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyT2K experimentFísicaSolar neutrino problem3. Good healthCosmic neutrino backgroundNeutrino detectorMeasurements of neutrino speedHigh Energy Physics::ExperimentNeutrino
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Measurement of Neutrino Oscillation Parameters from Muon Neutrino Disappearance with an Off-Axis Beam

2013

The T2K Collaboration reports a precision measurement of muon neutrino disappearance with an off-axis neutrino beam with a peak energy of 0.6 GeV. Near detector measurements are used to constrain the neutrino flux and cross section parameters. The Super-Kamiokande far detector, which is 295 km downstream of the neutrino production target, collected data corresponding to 3.01 x 10(20) protons on target. In the absence of neutrino oscillations, 205 +/- 17 (syst) events are expected to be detected while only 58 muon neutrino event candidates are observed. A fit to the neutrino rate and energy spectrum, assuming three neutrino flavors and normal mass hierarchy yields a best-fit mixing angle sin…

Particle physicsPhysics::Instrumentation and DetectorsSolar neutrinoAstrophysics::High Energy Astrophysical PhenomenaGeneral Physics and AstronomyFluxFOS: Physical sciencesddc:500.201 natural sciences7. Clean energyHigh Energy Physics - ExperimentNuclear physicsHigh Energy Physics - Experiment (hep-ex)0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Muon neutrino010306 general physicsNeutrino oscillationPhysics010308 nuclear & particles physics4. EducationHigh Energy Physics::PhenomenologyDetectorSolar neutrino problemNeutrino detectorMeasurements of neutrino speedFísica nuclearHigh Energy Physics::ExperimentNeutrino
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Gravitational Waves and Gamma-Rays from a Binary Neutron Star Merger: GW170817 and GRB 170817A

2017

On 2017 August 17, the gravitational-wave event GW170817 was observed by the Advanced LIGO and Virgo detectors, and the gamma-ray burst (GRB) GRB 170817A was observed independently by the Fermi Gamma-ray Burst Monitor, and the Anticoincidence Shield for the Spectrometer for the International Gamma-Ray Astrophysics Laboratory. The probability of the near-simultaneous temporal and spatial observation of GRB 170817A and GW170817 occurring by chance is $5.0\times 10^{-8}$. We therefore confirm binary neutron star mergers as a progenitor of short GRBs. The association of GW170817 and GRB 170817A provides new insight into fundamental physics and the origin of short gamma-ray bursts. We use the ob…

AstrofísicaGravitacióneutron star: binaryclose [binaries]Astronomy[ PHYS.ASTR ] Physics [physics]/Astrophysics [astro-ph]BATSE OBSERVATIONSgamma-ray burst: generalEQUIVALENCE PRINCIPLEEXTENDED EMISSIONastro-ph.HE; astro-ph.HEAstrophysicsKilonovageneral [gamma-ray burst]01 natural sciences7. Clean energyGeneral Relativity and Quantum Cosmologyphoton: velocityPROMPT EMISSIONLIGOclose gamma-ray burst: general gravitational waves [binaries]gravitational wave010303 astronomy & astrophysicsGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)BURST SPECTRAQCQBPhysicsastro-ph.HEHigh Energy Astrophysical Phenomena (astro-ph.HE)binaries: closeGRBEQUATION-OF-STATEviolation: Lorentzgamma ray: emissiongravitational wavesAstrophysics - High Energy Astrophysical PhenomenaGWradiation: electromagneticAfterglow Light CurvesAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesGeneral Relativity and Quantum Cosmology (gr-qc)Astrophysics::Cosmology and Extragalactic Astrophysicsgamma ray: burstinvariance: LorentzGW GRB LIGO Virgo Fermi BNSGLASTOptical Afterglows0103 physical sciencesgamma ray: detectorBinaries: close; gamma-ray burst: general; gravitational wavesSTFCFermi010308 nuclear & particles physicsGravitational waveVirgogravitational radiationRCUKAstronomy and AstrophysicsAstronomy and Astrophysictime delaysensitivityShapiro delayLIGORedshiftNeutron starVIRGOPhysics and AstronomyHOST GALAXYCPT VIOLATION13. Climate actiongravitationSpace and Planetary ScienceLUMINOSITY FUNCTIONVIEWING ANGLEbinaries: close; gamma-ray burst: general; gravitational waves; Astronomy and Astrophysics; Space and Planetary ScienceBNSspectrometerGamma-ray burst[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]redshift: measuredFermi Gamma-ray Space TelescopeAstrophysical Journal Letters
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