Long Term Results After Repair of Type A Acute Aortic Dissection According to False Lumen Patency.

Background. Late survival and freedom from retreatment on the descending aorta was evaluated after ascending aortic repair for type A acute aortic dissection (TAAAD). Methods. Between March 1992 and January 2006, 189 TAAAD patients (mean age, 52 11; range, 17 to 83 years) were included; of these, 58 had a patent false lumen, and 49 had Marfan syndrome. The descending aorta was evaluated postoperatively with computed tomography (CT). Late outcomes were assessed by Cox regression analysis and actuarial survival and freedom from retreatment by the Kaplan-Meier method. Mean follow-up was 88 44 months. Results. There were 38 (20%) late deaths. At 10 years, survival was 89.8% 2.1% for patients wi…

Fascite cranio-cervicale, dal quadro clinico al trattamento: esperienza personale

TOMOGRAFIA COMPUTERIZZATA MULTISTRATO E VALUTAZIONE CORONARICA NON INVASIVA

Pretreatment quality of life and functional status assessment significantly predict survival of elderly patients with advanced non-small-cell lung cancer receiving chemotherapy: a prognostic analysis of the multicenter Italian lung cancer in the elderly study

Purpose To study the prognostic value for overall survival of baseline assessment of functional status, comorbidity, and quality of life (QoL) in elderly patients with advanced non—small-cell lung cancer treated with chemotherapy. Patients and Methods Data from 566 patients enrolled onto the phase III randomized Multicenter Italian Lung Cancer in the Elderly Study (MILES) study were analyzed. Functional status was measured as activities of daily living (ADL) and instrumental ADL (IADL). The presence of comorbidity was assessed with a checklist of 33 items; items 29 and 30 of the European Organisation for Research and Treatment of Cancer (EORTC) core questionnaire QLQ-C30 (EORTC QLQ-C30) wer…

Vinorelbine plus cisplatinum for the treatment of stage IIIB and IV non small cell lung carcinoma

Thirty consecutive patients with stage IIIB-IV non small cell lung cancer were treated with a combination of cisplatin 80 mg/m2 on day 1 plus vinorelbine 25-30 mg/m2 on days 1, 8. This cycle was repeated every 3 weeks. The overall response rate was 46%, with 1 patient showing a complete response and 13 patients (43%) a partial response with a mean duration of 8.4+ months. Six patients had a stabilization and 10 progressed. The main toxicities were represented by myelosuppression and nausea/vomiting. Grade 3 leukopenia was seen in 33% of cases, grade 2 thrombocytopenia in 12%, and phlebitis in the injection vein in 16%. Mild constipation was also recorded. The combination of cisplatin plus v…

Association between +1059G/C CRP polymorphism and acute myocardial infarction in a cohort of patients from Sicily: a pilot study.

Genetic susceptibility to the coronary artery diseases

The origin of coronary arterydisease is the interaction between genetic predisposition and environmental influences.

Raro caso di papilloma invertito del sacco lacrimale con invasione dell’orbita

Managment clinico e chirurgico delle infezioni profonde del collo

La fascite necrotizzante (FN) è un’infezione dei tessuti molli caratterizzata da necrosi diffusa a rapida progressione dei tessuti sottocutanei e delle fasce ad essi annessi, potenzialmente letale. L’incidenza varia a seconda della localizzazione e tra tutte quella cranio-cervicale (FNCC) si presenta in 4/1000 casi di FN l’anno. Se pur rara negli ultimi anni si è assistito ad una maggiore evidenziazione clinica; ciò è da ascrivere ad una transitoria immunodepressione legata a malattie sistemiche in grado di compromettere i meccanismi di fagocitosi; I processi flogistici in grado di evolvere in FN sono prevalentemente infezioni dentarie (23%), ascessi peritonsillari (15%) ed infezioni a live…