0000000001295074

AUTHOR

V Maximo

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Asphyxia Activates P65 and Induces VEGF-A Gene Expression in Retina and Choroid from Newborn Piglets

2011

Objective: Exposure to lower oxygen causes oxidative stress and promotes angiogenesis. Asphyctic neonates have shown higher cord-blood vascular endothelial growth factor (VEGF). We hypothesized that retina and choroid having a different circulatory regulation (choroid lacks vascular auto-regulation) would acutely stimulate angiogenesis in response to short and severe hypoxemia.

AsphyxiaPathologymedicine.medical_specialtyRetinaFetusbusiness.industryAngiogenesismedicine.disease_causeeye diseasesVascular endothelial growth factorchemistry.chemical_compoundmedicine.anatomical_structureEndocrinologychemistryInternal medicinePediatrics Perinatology and Child HealthCirculatory systemmedicinesense organsChoroidmedicine.symptombusinessOxidative stressPediatric Research
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