Zur Frage der Ein- oder Mehrkernigkeit der Konidiosporen von Claviceps purpurea Tul. (Mutterkorn)

Indications actuelles de la pancréatographie et de la pancréatoscopie

L'importance de la pancreatographie endoscopique retrograde (PCER) diminue actuellement en raison de la disponibilite de techniques d'efficacite equivalente et depourvues de complications. L'angiopancreatographie (PCRM) et l'echoendoscopie sont au moins equivalentes dans le diagnostic des maladies pancreatiques et mettent en evidence les alterations canalaires avec une precision comparable. De plus, ces techniques renseignent au sujet des alterations parenchymateuses. Dans la mesure ou l'intervention endoscopique n'est pas necessaire, la PCRM et l'utrasonographie peuvent remplacer les techniques classiques de diagnostic par PCER. La PCER a sa place comme exploration prealable a une interven…

Neue technische Entwicklungen

Vom 1. 9. 1985 bis zum 31. 12. 1988 wurden 87 Anastomosen gefertigt; 59 wegen Sigmadivertikultitis, 21 bei Morbus Crohn/Colitis ulcerosa, 4 nach Radiatio und 3 nach ischamischer Kolitis. 47 manuelle Anastomosen, vorwiegend im rektosigmoidalen Ubergang stehen 40 Stapleranastomosen, besonders im oberen und mittleren Rektumdrittel gegenuber. Nach Klammernaht setzte die Stuhltatigkeit fruher ein, die Infusionsdauer war kurzer. Ein symptomatischer Nahtbruch entstand nach Anwendung des EEA-Premiumgerates. Kein Patient verstarb. Narbige Anastomosenstenosen entwickelten sich nicht. Besonders im oberen und mittleren Rektum stellen die Stapler eine wichtige Erganzung der chirurgischen Technik dar.

Interventionelle ERCP bei Patienten mit Cholestase: Häufigkeit und Antibiotikaresistenz der biliären Keimbesiedlung

Interventional ERCP in patients with cholestasis. Degree of biliary bacterial colonization and antibiotic resistance. Biliary obstruction together with bacterial colonization of the bile duct may lead to development of acute cholangitis. The aim of our prospective study was to investigate the presence and degree of biliary bacterial colonization by means of bile aspiration during ERCP in patients with biliary obstruction. Furthermore, we evaluated antibiotic therapy regimens, which would cover the bacterial species obtained by ERCP and subsequent culture in each patient. In addition, analysis of risk factors was performed that would predispose to the development of cholangitis.80 patients w…

Traitement endoscopique interventionnel de la douleur dans la pancréatite chronique

Dans la pancreatite chronique, la douleur est causee par differents mecanismes. La pression canalaire augmentee, les obstructions intracanalaires, les pseudo-kystes et les stenoses biliaires associees peuvent etre traites par endoscopie. Les outils de l’endoscopiste sont: la papillotomie, la pose de prothese du canal pancreatique et/ou biliaire, la dilatation des retrecissements pancreatiques, l’extraction de calculs combines a la lithotritie extracorporeale par onde de choc, le drainage naso-pancreatique transitoire, la lithotritie mecanique et la pancreatoscopie. Nous rapportons les resultats a moyen terme (r=234–1095 d) d’une etude prospective non controlee chez 68 patients entre 1992 et…

21. Mainzer Allergie-Workshop

Earth system data cubes unravel global multivariate dynamics

Understanding Earth system dynamics in light of ongoing human intervention and dependency remains a major scientific challenge. The unprecedented availability of data streams describing different facets of the Earth now offers fundamentally new avenues to address this quest. However, several practical hurdles, especially the lack of data interoperability, limit the joint potential of these data streams. Today, many initiatives within and beyond the Earth system sciences are exploring new approaches to overcome these hurdles and meet the growing interdisciplinary need for data-intensive research; using data cubes is one promising avenue. Here, we introduce the concept of Earth system data cu…

Coloration vitale du tractus gastro-intestinal

Au cours des dernieres annees, les methodes de coloration ont pris de plus en plus d’importance en endoscopie digestive. Le but de l’endoscopie diagnostique est de visualiser les structures epitheliales et de detecter les alterations de la muqueuse normale. Le pronostic defavorable de l’evolution des tumeurs gastro-intestinales requiert une detection precoce des anomalies des muqueuses et des methodes de therapie locale. Les video-endoscopes modernes a haute resolution permettent de visualiser de facon remarquable les fins details de l’epithelium. Cette visualisation de la surface epitheliale peut encore etre amelioree par une coloration complementaire. Les termes de «colorations vitales» e…

First measurement of the |t|-dependence of coherent J/ψ photonuclear production

The first measurement of the dependence on $|t|$, the square of the momentum transferred between the incoming and outgoing target nucleus, of coherent J/ψ photoproduction is presented. The data were measured with the ALICE detector in ultra-peripheral Pb-Pb collisions at a centre-of-mass energy per nucleon pair $\sqrt{s_{\rm NN}} = 5.02$ TeV with the J/$\psi$ produced in the central rapidity region $|y| < 0.8$, which corresponds to the small Bjorken-$x$ range $(0.3 − 1.4) \times 10 ^{−3}$. The measured $|t|$-dependence is not described by computations based only on the Pb nuclear form factor, while the photonuclear cross section is better reproduced by models including shadowing according t…

Chromoendoscopy with indigocarmine improves the detection of adenomatous and nonadenomatous lesions in the colon.

BACKGROUND AND STUDY AIMS Depressed early cancers and flat adenomas have a high potential for malignancy with possible infiltrating growth, despite the small size of the lesion. Japanese investigators have shown that early diagnosis and classification of these lesions is possible with the help of chromoendoscopy. The aim of this study, therefore, was to evaluate the usefulness of chromoendoscopy during routine colonoscopy. PATIENTS AND METHODS During routine colonoscopy, vital staining with indigocarmine solution (0.4 %, 1 - 10 ml) was performed on all visible lesions in 100 consecutive patients without visible inflammatory changes. If findings on macroscopic examination were unremarkable, …

Laser-stimulated two-step recombination of highly charged ions and electrons in a storage ring

Two-step resonant laser-stimulated recombination of highly charged ions was performed for the first time. Nd:YAG laser pulses overlapped with an Ar[sup 18+] beam in the electron cooler of the ESR storage ring at GSI induced transitions from the continuum to the [ital n]=81 state of hydrogenlike Ar[sup 17+]. To avoid reionization in the bending magnet before reaching the detector, the [ital n]=81 population was transferred to a state well below the reionization threshold by a Ti:sapphire laser. Tuning of this laser yielded the [ital n]=81 to 36 and 37 transition-line profiles. The two-step method provides access to detailed Rydberg spectroscopy in an electron beam environment.

Traitement de la pancréatite chronique. L’expérience allemande. Le point de vue de l’endoscopiste

Colonoscopy for screening of colorectal cancer. What are the news? Review

The goal of every routine endoscopy in the gut is the early diagnosis of malignant and premalignant changes of the mucosa. Chromo- and magnifying endoscopes are exciting new tools and offer detailed analysis of the colonic mucosal surface and pit pattern architecture. This review summarizes recent advances in endoscopic characterization of colorectal lesions using magnification endoscopy and chromoendoscopy. Surface analysis of the colon using chromoendoscopy allows a prediction between nonneoplastic and neoplastic lesions with high specificity. The precise delineation of the borders and a more detailed macroscopic analysis of the lesions are further advantages. In particular, flat adenomas…

Diagnostic précoce du cancer du pancréas. Mission impossible

Search for a common baryon source in high-multiplicity pp collisions at the LHC

Physics letters / B B811, 135849 (2020). doi:10.1016/j.physletb.2020.135849

Value of chromoendoscopy and magnification endoscopy in the evaluation of duodenal abnormalities: a prospective, randomized comparison.

Background and study aims Endoscopic staining methods are increasingly being used to evaluate lesions in the esophagus and colon. The aim of this prospective study was to investigate chromoendoscopy and magnification endoscopy for the evaluation of mucosal lesions in the duodenum. Patients and methods Consecutive patients were randomly assigned to undergo conventional endoscopy without staining (group A) or intravital staining of the duodenal mucosa with indigo carmine and evaluation with a conventional video endoscope (group B) or a magnification endoscope (group C). Visible lesions were characterized before and after staining, and biopsies were taken for histological assessment. Results A…

Détection du cancer colorectal et des lésions prémalignes par chromoscopie et endoscopie à optique grossissante

En Europe, le cancer colorectal (CCC) est la seconde cause de mortalite consecutive a une pathologie tumorale [1]. En depit des techniques chirurgicales eprouvees et des nouvelles formes de chimiotherapie, les tumeurs invasives, a l’exception des stades du debut, conservent encore a 5 ans des resultats de survie decevants, de l’ordre de 70 % avec envahissement metastatique proximal et seulement 6% en cas de metastase a distance [1]. Les taux de survie et de mortalite du CCR peuvent etre ameliores par une detection de cancer au debut a un stade preclinique. Par consequent, l’incidence du CCR peut etre reduite grâce a une detection endoscopique de lesions premalignes ou de cancers au debut. L…

The upgrade of the ALICE TPC with GEMs and continuous readout

Journal of Instrumentation 16(03), P03022 (2021). doi:10.1088/1748-0221/16/03/P03022

Early outcomes and complications following cardiac surgery in patients testing positive for coronavirus disease 2019: An international cohort study

The outbreak of severe acute respiratory syndromecoronavirus-2, the cause of coronavirus disease 2019 (COVID-19) in December 2019 represented a global emergency accounting for more than 2.5 million deaths worldwide.1 It has had an unprecedented influence on cardiac surgery internationally, resulting in cautious delivery of surgery and restructuring of services.2 Understanding the influence of COVID-19 on patients after cardiac surgery is based on assumptions from other surgical specialties and single-center studies. The COVIDSurg Collaborative conducted a multicenter cohort study, including 1128 patients, across 235 hospitals, from 24 countries demonstrating perioperative COVID-19 infection…

Dielectron production in proton-proton and proton-lead collisions at √sNN=5.02TeV

The first measurements of dielectron production at midrapidity (|ηe| &lt; 0.8) in proton–proton and proton–lead collisions at √sNN = 5.02 TeV at the LHC are presented. The dielectron cross section is measured with the ALICE detector as a function of the invariant mass mee and the pair transverse momentum pT, ee in the ranges mee &lt; 3.5 GeV/c2 and pT, ee &lt; 8 GeV/c, in both collision systems. In proton–proton collisions, the charm and beauty cross sections are determined at midrapidity from a fit to the data with two different event generators. This complements the existing dielectron measurements performed at √s = 7 and 13 TeV. The slope of the √s dependence of the three measurements is…

B(bar) -> X_s gamma rate and CP asymmetry within the aligned two-Higgs-doublet model

In the two-Higgs-doublet model the alignment of the Yukawa matrices in flavour space guarantees the absence of flavour-changing neutral currents at tree level, while introducing new sources for CP violation parametrized in a very economical way. This implies potentially large influence in a number of processes, b -> s gamma being a prominent example where rather high experimental and theoretical precision meet. We analyze the CP rate asymmetry in this inclusive decay and determine the resulting constraints on the model parameters. We demonstrate the compatibility with previously obtained limits. Moreover we extend the phenomenological analysis of the branching ratio, and examine the influen…

Scaling carbon fluxes from eddy covariance sites to globe: synthesis and evaluation of the FLUXCOM approach

FLUXNET comprises globally distributed eddy-covariance-based estimates of carbon fluxes between the biosphere and the atmosphere. Since eddy covariance flux towers have a relatively small footprint and are distributed unevenly across the world, upscaling the observations is necessary to obtain global-scale estimates of biosphere–atmosphere exchange. Based on cross-consistency checks with atmospheric inversions, sun-induced fluorescence (SIF) and dynamic global vegetation models (DGVMs), here we provide a systematic assessment of the latest upscaling efforts for gross primary production (GPP) and net ecosystem exchange (NEE) of the FLUXCOM initiative, where different machine learning methods…

Stimulation of T cells by autologous mononuclear leukocytes and epidermal cells in psoriasis.

Based on reports suggesting aberrant cell-mediated immunity and altered infiltration of immunocompetent cells into the skin in psoriasis, we studied the stimulation of T cells by autologous non-T mononuclear leukocytes (autologous mixed lymphocyte reaction, AMLR) and by epidermal cells isolated from lesional and clinically uninvolved skin in psoriasis (autologous mixed epidermal cell lymphocyte reaction, AMECLR). Age- and sex-matched individuals served as controls. We found that the AMLR in psoriasis (n = 11) was similar to that in healthy controls (n = 16); furthermore, cell proliferation was alike in the presence of either 5% AB-serum or autologous serum. By contrast, while the AMECLR in …

Ulcerative colitis - How can we improve surveillance colonoscopy?

Perspectives of Chromo and Magnifying Endoscopy

The goal of every routine endoscopy in the gut is the early diagnosis of malignant and premalignant changes of the mucosa. Chromo- and magnifying endoscopes are exciting new tools and offer detailed analysis of the colonic mucosal surface and pit pattern architecture. This review summarizes recent advances in endoscopic characterization of colorectal lesions using magnification endoscopy and chromoendoscopy. Surface analysis of the colon using chromoendoscopy allows a prediction between non-neoplastic and neoplastic lesions with high specificity. The precise delineation of the borders and a more detailed macroscopic analysis of the lesions are further advantages. In particular, flat adenoma…

Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score

The British journal of surgery 108(11), 1274-1292 (2021). doi:10.1093/bjs/znab183

Measurements of mixed harmonic cumulants in Pb–Pb collisions at sNN=5.02 TeV

Correlations between moments of different flow coefficients are measured in Pb–Pb collisions at sNN=5.02 TeV recorded with the ALICE detector. These new measurements are based on multiparticle mixed harmonic cumulants calculated using charged particles in the pseudorapidity region |η|&lt;0.8 with the transverse momentum range 0.2&lt;pT&lt;5.0 GeV/c. The centrality dependence of correlations between two flow coefficients as well as the correlations between three flow coefficients, both in terms of their second moments, are shown. In addition, a collection of mixed harmonic cumulants involving higher moments of v2 and v3 is measured for the first time, where the characteristic signature of ne…

The Belle II Physics Book

cd. autorów: L. Cao48,‡, G. Caria145,‡, G. Casarosa57,‡, C. Cecchi56,‡,D. Cˇ ervenkov10,‡,M.-C. Chang22,‡, P. Chang92,‡, R. Cheaib146,‡, V. Chekelian83,‡, Y. Chen154,‡, B. G. Cheon28,‡, K. Chilikin77,‡, K. Cho70,‡, J. Choi14,‡, S.-K. Choi27,‡, S. Choudhury35,‡, D. Cinabro170,‡, L. M. Cremaldi146,‡, D. Cuesta47,‡, S. Cunliffe16,‡, N. Dash33,‡, E. de la Cruz Burelo9,‡, E. de Lucia52,‡, G. De Nardo54,‡, †Editor. ‡Belle II Collaborator. §Theory or external contributing author. M. De Nuccio16,‡, G. De Pietro59,‡, A. De Yta Hernandez9,‡, B. Deschamps129,‡, M. Destefanis60,‡, S. Dey116,‡, F.Di Capua54,‡, S.Di Carlo75,‡, J. Dingfelder129,‡, Z. Doležal10,‡, I. Domínguez Jiménez125,‡, T.V. Dong30,26,…

Improved Sedation in Diagnostic and Therapeutic ERCP: Propofol is an Alternative to Midazolam

Background and Study Aims: Adequate sedation of the patient is required for diagnostic and therapeutic endoscopic retrograde cholangiopancreatography (ERCP). The anesthetic propofol, with its shorter half-life, affording better control, offers an alternative to the benzodiazepine midazolam. The aim of this randomized, controlled, unblinded study was to compare prospectively the quality of sedation under propofol and midazolam in patients undergoing ERCP. Patients and Methods: A total of 80 patients were randomized to sedation with propofol alone (n=40) or midazolam alone (n = 40). Blood pressure, pulse, and oxygen saturation were measured. Midazolam was given by the endoscopist and titrated…

First experiments with the heidelberg test storage ring TSR

Abstract The Heidelberg heavy ion test storage ring TSR started operation in May 1988. The lifetimes of the ion beams observed in the first experiments can be explained by interactions with the residual gas. Multiple Coulomb scattering, single Coulomb scattering, electron capture and electron stripping are the relevant processes. Electron cooling of ions as heavy as O 8+ has been observed for the first time. With increasing particle number, the longitudinal Schottky noise spectrum becomes dominated by collective waves for cooled beams, allowing a determination of velocities of sound. After correcting for these coherent distortions fo the Schottky spectrum, the longitudinal beam temperature …

CCDC 699494: Experimental Crystal Structure Determination

Related Article: M.Jung, A.Sharma, D.Hinderberger, S.Braun, U.Schatzschneider, E.Rentschler|2009|Eur.J.Inorg.Chem.||1495|doi:10.1002/ejic.200801248

CCDC 699684: Experimental Crystal Structure Determination

Related Article: M.Jung, A.Sharma, D.Hinderberger, S.Braun, U.Schatzschneider, E.Rentschler|2009|Eur.J.Inorg.Chem.||1495|doi:10.1002/ejic.200801248

CCDC 699607: Experimental Crystal Structure Determination

Related Article: M.Jung, A.Sharma, D.Hinderberger, S.Braun, U.Schatzschneider, E.Rentschler|2009|Eur.J.Inorg.Chem.||1495|doi:10.1002/ejic.200801248

CCDC 699496: Experimental Crystal Structure Determination

Related Article: M.Jung, A.Sharma, D.Hinderberger, S.Braun, U.Schatzschneider, E.Rentschler|2009|Eur.J.Inorg.Chem.||1495|doi:10.1002/ejic.200801248

CCDC 699605: Experimental Crystal Structure Determination

Related Article: M.Jung, A.Sharma, D.Hinderberger, S.Braun, U.Schatzschneider, E.Rentschler|2009|Inorg.Chem.|48|7244|doi:10.1021/ic9006857

CCDC 699685: Experimental Crystal Structure Determination

Related Article: M.Jung, A.Sharma, D.Hinderberger, S.Braun, U.Schatzschneider, E.Rentschler|2009|Inorg.Chem.|48|7244|doi:10.1021/ic9006857

CCDC 699686: Experimental Crystal Structure Determination

Related Article: M.Jung, A.Sharma, D.Hinderberger, S.Braun, U.Schatzschneider, E.Rentschler|2009|Inorg.Chem.|48|7244|doi:10.1021/ic9006857

CCDC 699495: Experimental Crystal Structure Determination

Related Article: M.Jung, A.Sharma, D.Hinderberger, S.Braun, U.Schatzschneider, E.Rentschler|2009|Eur.J.Inorg.Chem.||1495|doi:10.1002/ejic.200801248