0000000001300932

AUTHOR

S. Perrin

showing 11 related works from this author

A New Prognosis Score to Predict Mortality After Acute Pneumonia in Very Elderly Patients

2016

International audience; Objectives: Acute pneumonia (AP) induces an excess of mortality among the elderly. We evaluated the value of a new predictive biomarker index compared to usual prognosis scores for predicting in-hospital and 1-year mortalities in elderly inpatients with AP.Design: Retrospective study in 6 clinical departments of a university hospital.Setting: Burgundy university hospital (France).Participants: All patients aged 75 and over with AP and hospitalized between January 1 and June 30, 2013, in the departments of medicine (5) and intensive care (1) of our university hospital.Measurements: A new index, which we named UBMo, was created by multiplying the uremia (U in the formu…

Malecommunity-acquired pneumoniaPneumonia severity indexseveritysepsis0302 clinical medicineElderlyadultsscoreHospital Mortality030212 general & internal medicineProspective cohort studyGeneral NursingAged 80 and overvalidation[SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyHealth PolicyMortality rateGeneral Medicinecohort3. Good healthAcute DiseaseFemaleFranceterm survivalmanagementmedicine.medical_specialtyhospitalized-patients[ SDV.MHEP.GEG ] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology03 medical and health sciencesPredictive Value of TestsIntensive careInternal medicinemedicineHumanspneumoniaIntensive care medicineAgedRetrospective Studiesbusiness.industrybiomarkersRetrospective cohort studymedicine.diseasemortalityUremiaPneumoniaBlood pressure030228 respiratory systemprognosisGeriatrics and Gerontologybusiness
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Successful management of heparin-induced thrombocytopenia using argatroban in a very old woman: a case report.

2012

Thrombosis due to heparin-induced thrombocytopenia (HIT) is rare but has a severe prognosis. Its management is not always easy, particularly in old patients with renal insufficiency. A 95-year-old woman was hospitalized for dyspnea. Curative treatment with unfractionated heparin was started because pulmonary embolism was suspected. Disseminated intravascular coagulation was then suspected because of thrombocytopenia, hypoprothrombinemia, hypofibrinogenemia, and a positive ethanol gelation test. The first immunoassay for HIT was negative. On the 12th day of hospitalization, bilateral cyanosis of the toes occurred associated with recent deep bilateral venous and arterial thrombosis at duplex …

Disseminated intravascular coagulationmedicine.medical_specialtybusiness.industrylcsh:Rlcsh:MedicineCase ReportGeneral MedicineHeparinHypofibrinogenemiamedicine.diseaseThrombosisArgatrobanSurgeryPulmonary embolismHeparin-induced thrombocytopeniamedicineHypoprothrombinemiabusinessmedicine.drugCase reports in medicine
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Blood Transfusion in Elderly Patients with Acute Myocardial Infarction: Data from the RICO Survey.

2017

Red blood cell transfusion benefit during acute myocardial infarction remains unclear in the elderly. We aimed to assess the transfusion impact on 1-year mortality in acute myocardial infarction patients aged ≥65 years, according to their age and hemoglobin nadir.We included 3316 consecutive patients with acute myocardial infarction aged ≥65 years from the "obseRvatoire des Infarctus de Côte d'Or" (RICO) survey. They were categorized according to their hemoglobin nadir (≤8,8 to ≤10, and10 g/dL) and age (80 or ≥80 years).A total of 1906 patients (57%) were 65-79 years old, and 1410 (43%) were aged ≥80 years, of whom 103 (5%) and 145 (10%) patients received red blood cell transfusion, respect…

Malemedicine.medical_specialtyBlood transfusionAnemiamedicine.medical_treatmentMyocardial Infarction030204 cardiovascular system & hematology03 medical and health sciencesHemoglobins0302 clinical medicineOlder patientsInternal medicinemedicineHumansIn patientBlood Transfusion030212 general & internal medicineMyocardial infarctionProspective StudiesAgedAged 80 and overbusiness.industryAnemiaGeneral Medicinemedicine.diseaseConfidence intervalSurgeryTreatment OutcomeFemaleHemoglobinFrancebusinessNadir (topography)The American journal of medicine
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Potentially inappropriate use of furosemide in a very elderly population: An observational study

2017

International audience; ObjectiveLittle is known about furosemide prescription modalities in elderly people. We describe furosemide prescription in ambulatory elderly patients.MethodsAll patients aged over 80 years, affiliated to Mutualité Sociale Agricole de Bourgogne, a French regional health insurance plan, with a medical prescription delivered in March 2015, were retrospectively included.ResultsAmong 15 141 patients with a median age of 86 years, comprising 61.3% of women, 3937 patients (26%) had a prescription for furosemide. Severe heart failure was the most common chronic comorbidity (27.7%). Furosemide was considered a long-term therapy for almost all patients (98.7% with prescripti…

Liver CirrhosisMalePediatricsmedicine.medical_specialtyAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsInappropriate Prescribing[ SDV.MHEP.GEG ] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology030204 cardiovascular system & hematologyDrug PrescriptionsNephropathy03 medical and health sciences0302 clinical medicineFurosemidemedicineHumans030212 general & internal medicineMedical prescriptionRenal Insufficiency ChronicDiureticsRetrospective StudiesAged 80 and overHeart Failurebusiness.industryAge FactorsFurosemideRetrospective cohort studyGeneral Medicinemedicine.diseaseComorbidityHeart failureAmbulatoryObservational studyFemalebusinessmedicine.drug
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Measurements of mixed harmonic cumulants in Pb–Pb collisions at sNN=5.02 TeV

2021

Correlations between moments of different flow coefficients are measured in Pb–Pb collisions at sNN=5.02 TeV recorded with the ALICE detector. These new measurements are based on multiparticle mixed harmonic cumulants calculated using charged particles in the pseudorapidity region |η|<0.8 with the transverse momentum range 0.2<pT<5.0 GeV/c. The centrality dependence of correlations between two flow coefficients as well as the correlations between three flow coefficients, both in terms of their second moments, are shown. In addition, a collection of mixed harmonic cumulants involving higher moments of v2 and v3 is measured for the first time, where the characteristic signature of ne…

Quantum chromodynamicsPhysicsNuclear and High Energy PhysicsLarge Hadron Collider010308 nuclear & particles physics01 natural sciencesCharged particleNuclear physicsPseudorapidity0103 physical sciencesHarmonicRapidity010306 general physicsAnisotropyCumulantPhysics Letters B
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La couverture vaccinale contre la grippe saisonnière du personnel soignant en gériatrie : mise au point

2016

Resume Position du probleme La vaccination antigrippale des professionnels de sante semble representer l’une des actions preventives des plus efficaces face a une pathologie a haut risque d’epidemie nosocomiale et potentiellement grave en milieu geriatrique. Ce travail avait pour objectif de faire une mise au point sur le statut vaccinal antigrippal chez le personnel soignant en geriatrie et les raisons expliquant leur reticence vis-a-vis de cette vaccination, afin d’emettre des propositions d’amelioration de la couverture vaccinale. Methode Une recherche bibliographique des articles publies depuis 2000 dans le domaine de la geriatrie, des maladies infectieuses ou de la pneumologie a ete re…

0301 basic medicine03 medical and health sciences0302 clinical medicineEpidemiologybusiness.industry030106 microbiologyVirus influenzaPublic Health Environmental and Occupational HealthMedicine030212 general & internal medicinebusinessVirologyHumanitiesRevue d'Épidémiologie et de Santé Publique
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Iléite à cytomégalovirus chez une personne âgée non immunodéprimée : à propos d’une observation

2012

Resume Introduction Les ileites a cytomegalovirus surviennent rarement chez l’immunocompetent. Observation Une femme, âge de 88 ans, presentait une douleur intense de la fosse iliaque droite. La C-reactive proteine etait elevee et associee a une hyperleucocytose a polynucleaires neutrophiles. La coloscopie revelait un aspect tres ulcere et inflammatoire de la muqueuse ileale terminale. L’analyse anatomopathologique des biopsies retrouvait un effet cytopathogene typique avec cellules ballonisees et inclusions intranucleaires, confirme par un immunomarquage positif a l’anticorps anti-cytomegalovirus. La recherche de cytomegalovirus par PCR dans le plasma etait positive. L’evolution clinico-bi…

GastroenterologyInternal MedicineLa Revue de Médecine Interne
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First measurement of the |t|-dependence of coherent J/ψ photonuclear production

2021

The first measurement of the dependence on $|t|$, the square of the momentum transferred between the incoming and outgoing target nucleus, of coherent J/ψ photoproduction is presented. The data were measured with the ALICE detector in ultra-peripheral Pb-Pb collisions at a centre-of-mass energy per nucleon pair $\sqrt{s_{\rm NN}} = 5.02$ TeV with the J/$\psi$ produced in the central rapidity region $|y| < 0.8$, which corresponds to the small Bjorken-$x$ range $(0.3 − 1.4) \times 10 ^{−3}$. The measured $|t|$-dependence is not described by computations based only on the Pb nuclear form factor, while the photonuclear cross section is better reproduced by models including shadowing according t…

heavy ion: scatteringnucleon: pairVDP::Matematikk og Naturvitenskap: 400::Fysikk: 430::Kjerne- og elementærpartikkelfysikk: 431nucl-ex01 natural sciencesSquare (algebra)ALICEJ/psi(3100): photoproduction[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Nuclear ExperimentQuantum chromodynamicsPhysicsPhysicsForm factor (quantum field theory)ultra-peripheral collisionsdependence [impact parameter]J/psi ALICE Pb-Pb collisionsBalitsky-Kovchegov equationQuarkoniumddc:3. Good healthPHOTOPRODUCTIONshadowingNucleonParticle Physics - ExperimentPB-PB COLLISIONSNuclear and High Energy PhysicsQC1-999nucleus: form factor[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]MomentumNuclear physicsPHYSICSCross section (physics)heavy-ion collisions ultra-peripheral collisions quarkoniaphotoproduction [J/psi(3100)]scattering [heavy ion]0103 physical sciencesNuclear Physics - Experimentddc:530Rapidity5020 GeV-cms/nucleonHeavy Ion experiments010306 general physicsimpact parameter: dependencehep-ex010308 nuclear & particles physicsnucleus: targetpair [nucleon]photonuclear productionheavy-ion collisionsquarkoniaform factor [nucleus]PB-PB COLLISIONS; PHOTOPRODUCTION; PHYSICStarget [nucleus]J/PsicoherenceJ/psi(3100): photoproduction ; impact parameter: dependence ; nucleus: form factor ; nucleus: target ; nucleon: pair ; heavy ion: scattering ; coherence ; Balitsky-Kovchegov equation ; shadowing ; rapidity ; ALICE ; experimental results ; 5020 GeV-cms/nucleonrapidityphotonuclear production J/Psi Pb-Pb collisionsHigh Energy Physics::Experimentexperimental results
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Dielectron production in proton-proton and proton-lead collisions at √sNN=5.02TeV

2020

The first measurements of dielectron production at midrapidity (|ηe| &lt; 0.8) in proton–proton and proton–lead collisions at √sNN = 5.02 TeV at the LHC are presented. The dielectron cross section is measured with the ALICE detector as a function of the invariant mass mee and the pair transverse momentum pT, ee in the ranges mee &lt; 3.5 GeV/c2 and pT, ee &lt; 8 GeV/c, in both collision systems. In proton–proton collisions, the charm and beauty cross sections are determined at midrapidity from a fit to the data with two different event generators. This complements the existing dielectron measurements performed at √s = 7 and 13 TeV. The slope of the √s dependence of the three measurements is…

Nuclear and High Energy Physics:Kjerne- og elementærpartikkelfysikk: 431 [VDP]ProtonHadronNuclear Theorydielectrondielectron production01 natural sciences7. Clean energyNuclear physicshadron-ion interactionshadron-hadron collisions; dielectron production;Ionic Collisionsdielectron cross sectiondielectron nuclear modification factor0103 physical sciencesInvariant massDielectronCharm (quantum number)Dielectron; hadron-hadron interactions; hadron-ion interactionsPhysics::Atomic PhysicsIonic Collisions; Relativistic Heavy-ion Collisions; Quark-Gluon Plasma010306 general physicsNuclear ExperimentQuantum chromodynamicsPhysicsLarge Hadron Collider010308 nuclear & particles physicsPhysicsVDP::Kjerne- og elementærpartikkelfysikk: 431hadron-hadron interactionNuclear matterhadron-hadron collisionsNATURAL SCIENCES. Physics.ALICE LHC proton-lead collisions proton-proton collisionsPRIRODNE ZNANOSTI. Fizika.:Nuclear and elementary particle physics: 431 [VDP]VDP::Nuclear and elementary particle physics: 431dielectron ; LHC ; dielectron cross section ; dielectron nuclear modification factorQuark–gluon plasmaQuark-Gluon PlasmaHigh Energy Physics::ExperimentLHChadron-hadron interactionsRelativistic Heavy-ion Collisions
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CCDC 117866: Experimental Crystal Structure Determination

1999

Related Article: S.Perrin, K.Monnier, B.Laude, M.Kubicki, O.Blacque|1999|Eur.J.Org.Chem.|1999|297|doi:10.1002/(SICI)1099-0690(199901)1999:13.0.CO;2-J

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameterstrans-(Ethyl 36-diphenyl-3-p-tolylamino-34-dihydro-2-pyridone-4-carboxylate)Experimental 3D Coordinates
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CCDC 101489: Experimental Crystal Structure Determination

1999

Related Article: S.Perrin, K.Monnier, B.Laude, M.Kubicki, O.Blacque|1999|Eur.J.Org.Chem.|1999|297|doi:10.1002/(SICI)1099-0690(199901)1999:13.0.CO;2-J

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersEthyl 12-dihydro-2-oxo-36-diphenyl-4-pyridinecarboxylateExperimental 3D Coordinates
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