0000000001304390
AUTHOR
Valentina M. Breising
Electrochemical synthesis of carbazoles by dehydrogenative coupling reaction
Abstract A constant current protocol, employing undivided cells, a remarkably low supporting electrolyte concentration, inexpensive electrode materials, and a straightforward precursor synthesis enabling a novel access to N‐protected carbazoles by anodic N,C bond formation using directly generated amidyl radicals is reported. Scalability of the reaction is demonstrated and an easy deblocking of the benzoyl protecting group is presented.
Electrochemical Formation of 3,5-Diimido-1,2-dithiolanes by Dehydrogenative Coupling
A synthetic approach to the cyclic disulfide moiety of 3,5-diimido-1,2-dithiolane derivatives starting with readily available precursors including the electrochemical coupling of dithioanilides is developed. The electrochemical key step provides sustainable synthetic access in high yields, using a very simple electrolysis setup.
Electrochemical formation of N,N′-diarylhydrazines by dehydrogenative N–N homocoupling reaction
Hydrazines represent a class of compounds of high interest due to their applicability as versatile starting materials in many important transformations. Herein, we report a synthetic approach to hydrazine derivatives using commercially available anilines and an anodic dehydrogenative N-N coupling reaction as the key step.
Electrochemical Synthesis of 5-Aryl-phenanthridin-6-one by Dehydrogenative N,C Bond Formation.
Currently, the general synthesis of 5-aryl-phenanthridin-6-ones relies on the involvement of metal catalysis. Despite the urgent demand for green alternatives, avoiding synthetic routes that require transition metals for key roles is still challenging. Electrochemical efforts employing a constant potential protocol in divided cells revealed a possible alternative to the catalytic approach. A constant current protocol, undivided cells, and a remarkably low supporting electrolyte concentration enable a novel access to N-aryl-phenanthridin-6-ones by anodic N,C bond formation using directly generated amidyl radicals. Easy accessible starting materials, a broad scope of applicable functional gro…
CCDC 1866675: Experimental Crystal Structure Determination
Related Article: Anton Kehl, Valentina M. Breising, Dieter Schollmeyer, Siegfried R. Waldvogel|2018|Chem.-Eur.J.|24|17230|doi:10.1002/chem.201804638
CCDC 1979131: Experimental Crystal Structure Determination
Related Article: Valentina M. Breising, Jacob M. Kayser, Anton Kehl, Dieter Schollmeyer, Johannes C. Liermann, Siegfried R. Waldvogel|2020|Chem.Commun.|56|4348|doi:10.1039/D0CC01052A
CCDC 1866690: Experimental Crystal Structure Determination
Related Article: Valentina M. Breising, Tile Gieshoff, Anton Kehl, Vincent Kilian, Dieter Schollmeyer, Siegfried R. Waldvogel|2018|Org.Lett.|20|6785|doi:10.1021/acs.orglett.8b02904
CCDC 1986341: Experimental Crystal Structure Determination
Related Article: Anton Kehl, Niclas Schupp, Valentina M. Breising, Dieter Schollmeyer, Siegfried R. Waldvogel|2020|Chem.-Eur.J.|26|15847|doi:10.1002/chem.202003430