0000000001305737
AUTHOR
Tomislav Friščić
showing 9 related works from this author
Cocrystal trimorphism as a consequence of the orthogonality of halogen- and hydrogen-bonds synthons.
2019
True trimorphic cocrystals, i.e. multi-component molecular crystals of identical composition that exhibit three polymorphic structures, are exceedingly rare and so far no halogen-bonded cocrystal system has been reported to exhibit trimorphism. Here we describe a unique example of a trimorphic cocrystal exhibiting both hydrogen and halogen bonds in which the differences between polymorphs reveal their orthogonality, evident by the apparently independent variation of well-defined hydrogen- and halogen-bonded motifs. peerReviewed
Assembly and dichroism of a four-component halogen-bonded metal-organic cocrystal salt solvate involving dicyanoaurate(I) acceptors
2017
We describe the use of dicyanoaurate ions as linear ditopic metal–organic acceptors for the halogen bond-driven assembly of a dichroic metal–organic cocrystal based on azobenzene chromophores. Structural analysis by single crystal X-ray diffraction revealed that the material is a four-component solid, consisting of anticipated anionic metal–organic halogen-bonded chains based on dicyanoaurate ions, as well as complex potassium-based cations and discrete molecules of the crown ether 15-crown-5. Importantly, the structural analysis revealed the parallel alignment of the halogen-bonded chains required for dichroic behaviour, confirming that crystal engineering principles developed for the desi…
Real-Time Observation of “Soft” Magic-Size Clusters during Hydrolysis of the Model Metallodrug Bismuth Disalicylate
2021
International audience; Colloidal bismuth therapeutics have been used for hundreds of years, yet remain mysterious. Here we report an X-ray pair distribution function (PDF) study of the solvolysis of bismuth disalicylate, a model for the metallodrug bismuth subsalicylate (Pepto-Bismol). This reveals catalysis by traces of water, followed by multistep cluster growth. The ratio of the two major species, {Bi9O7} and {Bi38O44}, depends on exposure to air, time, and the solvent. The solution-phase cluster structures are of significantly higher symmetry in comparison to solid-state analogues, with reduced off-center Bi3+ displacements. This explains why such “magic-size” clusters can be both stab…
CCDC 1831925: Experimental Crystal Structure Determination
2019
Related Article: Filip Topić, Katarina Lisac, Mihails Arhangelskis, Kari Rissanen, Dominik Cinčić, Tomislav Friščić|2019|Chem.Commun.|55|14066|doi:10.1039/C9CC06735C
CCDC 1831927: Experimental Crystal Structure Determination
2019
Related Article: Filip Topić, Katarina Lisac, Mihails Arhangelskis, Kari Rissanen, Dominik Cinčić, Tomislav Friščić|2019|Chem.Commun.|55|14066|doi:10.1039/C9CC06735C
CCDC 1539033: Experimental Crystal Structure Determination
2017
Related Article: Jan-Constantin Christopherson, Karlie P. Potts, Oleksandr S. Bushuyev, Filip Topić, Igor Huskić, Kari Rissanen, Christopher J. Barrett, Tomislav Friščić|2017|Faraday Discuss.|203|441|doi:10.1039/C7FD00114B
CCDC 1831924: Experimental Crystal Structure Determination
2019
Related Article: Filip Topić, Katarina Lisac, Mihails Arhangelskis, Kari Rissanen, Dominik Cinčić, Tomislav Friščić|2019|Chem.Commun.|55|14066|doi:10.1039/C9CC06735C
CCDC 1831926: Experimental Crystal Structure Determination
2019
Related Article: Filip Topić, Katarina Lisac, Mihails Arhangelskis, Kari Rissanen, Dominik Cinčić, Tomislav Friščić|2019|Chem.Commun.|55|14066|doi:10.1039/C9CC06735C
CCDC 1831928: Experimental Crystal Structure Determination
2019
Related Article: Filip Topić, Katarina Lisac, Mihails Arhangelskis, Kari Rissanen, Dominik Cinčić, Tomislav Friščić|2019|Chem.Commun.|55|14066|doi:10.1039/C9CC06735C