0000000001320382

AUTHOR

Kevin Troulé

showing 2 related works from this author

Growth rate controls mRNA turnover in steady and non-steady states.

2016

Gene expression has been investigated in relation with growth rate in the yeast Saccharomyces cerevisiae, following different experimental strategies. The expression of some specific gene functional categories increases or decreases with growth rate. Our recently published results have unveiled that these changes in mRNA concentration with growth depend on the relative alteration of mRNA synthesis and decay, and that, in addition to this gene-specific transcriptomic signature of growth, global mRNA turnover increases with growth rate. We discuss here these results in relation with other previous and concurrent publications, and we add new evidence which indicates that growth rate controls m…

0301 basic medicineRNA StabilitySaccharomyces cerevisiaeSaccharomyces cerevisiaeyeastTranscriptome03 medical and health sciencesTranscription (biology)Gene Expression Regulation FungalGene expressionmRNA stabilityGrowth rateRNA MessengerMolecular BiologyGenePoint of ViewMessenger RNAbiologyRNA FungalCell Biologybiology.organism_classificationMolecular biologyYeastCell biology030104 developmental biologygrowth rateGene expressiontranscriptionRNA biology
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Growth rate controls mRNA turnover in steady and non-steady states

2020

Gene expression has been investigated in relation with growth rate in the yeast Saccharomyces cerevisiae, following different experimental strategies. The expression of some specific gene functional categories increases or decreases with growth rate. Our recently published results have unveiled that these changes in mRNA concentration with growth depend on the relative alteration of mRNA synthesis and decay, and that, in addition to this gene-specific transcriptomic signature of growth, global mRNA turnover increases with growth rate. We discuss here these results in relation with other previous and concurrent publications, and we add new evidence which indicates that growth rate controls m…

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