Clinical features and follow-up in patients with 22q11.2 deletion syndrome

Objective To investigate the clinical manifestations at diagnosis and during follow-up in patients with 22q11.2 deletion syndrome to better define the natural history of the disease. Study design A retrospective and prospective multicenter study was conducted with 228 patients in the context of the Italian Network for Primary Immunodeficiencies. Clinical diagnosis was confirmed by cytogenetic or molecular analysis. Results The cohort consisted of 112 males and 116 females; median age at diagnosis was 4 months (range 0 to 36 years 10 months). The diagnosis was made before 2 years of age in 71% of patients, predominantly related to the presence of heart anomalies and neonatal hypocalcemia. In…

Alle origini della mediterraneità nel modernismo di Ernesto Basile. La “casetta“ del pittore Rocco Lentini nella città balneare di Mondello

A survey on features of allergic rhinitis in children

Objective: A number of epidemiologic studies evaluated the prevalence of allergic rhinitis (AR), but few data are available on its different clinical presentations. We addressed this survey to assess the features of AR in children and adolescents. Methods: Thirty-five centers in Italy included 2623 pediatric patients with rhinitis, of whom 2319 suffered from AR, while 304 had other kinds of rhinitis. For each patient a standardized questionnaire was filled in, including ARIA classification, the duration of symptoms, the allergen identified as clinically relevant, the co-morbidities, the kind of treatment, the response to treatment, the satisfaction with the treatment, and the feasibility of…

Servizio Civile Nazionale, Associazionismo e Volontariato

il contributo contiene una analisi del percorso che ha condotto all'istituzione del Servizio Civile Nazionale ed una riflessione sugli scenari sociali e politici che ne hanno determinato lo sviluppo. Particolare attenzione è stata data inoltre al ruolo del volontariato e dell'associazionismo ed alla loro capacità di innescare meccanismi di autocoscientizzazione, di autogoverno e di partecipazione alla cittadinanza attiva.