6533b7cefe1ef96bd1256fbf

RESEARCH PRODUCT

Use of bone scintigraphy in the early diagnosis of bisphosphonate related osteonecrosis of the jaw. Case report and review of the literature

Mercedes Villegas-calvoPaolo CariatiJosé-darío Sánchez-lópezJacobo Cambil-martínMaría-luisa Moreno-martin

subject

Chemotherapymedicine.medical_specialtyOral Medicine and Pathologymedicine.diagnostic_testbusiness.industrymedicine.medical_treatmentPostoperative radiotherapyEarly detectionBone metastasisCase Report030206 dentistryBisphosphonate:CIENCIAS MÉDICAS [UNESCO]medicine.disease03 medical and health sciences0302 clinical medicineBreast cancerBone scintigraphy030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASmedicineRadiologybusinessOsteonecrosis of the jawGeneral Dentistry

description

The main aim of the present report is to show the potential utility of bone scintigraphy for the diagnosis of jaw osteonecrosis. We report the history of a 62-year-old woman underwent breast cancer surgery in 2010. Moreover, patient received postoperative radiotherapy and chemotherapy. Intravenous bisphosphonates were also added to the treatment strategy to reduce the risk of bone metastasis. However, a hypermetabolic focus on left hemimandible was evidenced with a bone scintigraphy during follow up. After a careful study, the diagnosis of Bisphosphonate Related Ostneonecrosis of the Jaw (BRONJ) was carried out. This case highlights that bone scintigraphy may be extremely helpful for the early detection of BRONJ in high risk patient. Key words:Bone scintigraphy, mandibular osteonecrosis, bisphosphonates.

yearjournalcountryeditionlanguage
2018-12-01
10.4317/jced.55248http://hdl.handle.net/10550/69466