6533b7cefe1ef96bd1257961

RESEARCH PRODUCT

The use of fish bile metabolite analyses as exposure biomarkers to pulp and paper mill effluents

Harri LeppänenSanna MarttinenAimo Oikari

subject

Environmental EngineeringHealth Toxicology and MutagenesisMetaboliteengineering.materialcomplex mixtureschemistry.chemical_compoundfoodstomatognathic systemCoregonus lavaretusEnvironmental ChemistryWater pollutionEffluentSalmonidaebiologyWaste managementfood.dishbusiness.industryPulp (paper)digestive oral and skin physiologytechnology industry and agriculturePublic Health Environmental and Occupational HealthPaper millGeneral MedicineGeneral Chemistrybiology.organism_classificationPulp and paper industryPollutionchemistryengineeringSewage treatmentbusiness

description

The exposure of caged one-year-old whitefish (Coregonus lavaretus) to wood extractives and chlorophenolics from pulp and paper mill effluents in Lake Saimaa (SE Finland) was investigated. Whitefish were exposed at 17 locations affected by effluents from pulp and paper mills and at 5 reference areas. Resin and fatty acids and chlorophenolics in bile were analysed by GC and GC-MS. Cholesterol concentration in bile was also measured. Results show that despite of process changes to ECF and waste water treatment improvements employed by the pulp and paper industry in the study area, it is still possible to detect elevated concentrations of these substances in the bile of fish exposed in the vicinity of a pulp and paper mill.

https://doi.org/10.1016/s0045-6535(97)10226-0