6533b7cffe1ef96bd125982a
RESEARCH PRODUCT
Friessche Verschiebung vonortho- undpara-Methoxyphenylacetaten. Die Bildung von Ketoestern
Robert MartinNicole GrosVolker BöhmerHermann Kämmerersubject
chemistry.chemical_compoundResidue (chemistry)NitromethanechemistryFries rearrangementSide reactionOrganic chemistryGeneral ChemistryMedicinal chemistryCatalysisdescription
During theFries rearrangement ofo- andp-methoxy phenyl acetates with AlCl3 in nitromethane at 20°C substitution occurs mainly in thep-position of the phenolic residue to yieldp-acylphenols. Larger quantities ofo-acylphenols are obtained only, if thisp-position is already substituted. Witho-methoxy phenyl acetates the substitution of the acid residue to yield ketoesters is observed as a side reaction. Those ketoesters are obtained as main products if TiCl4 is taken as a catalyst.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1980-01-01 | Monatshefte f�r Chemie |