6533b7d0fe1ef96bd125a1d5

RESEARCH PRODUCT

Biochemistry and genetics of insect resistance toBacillus thuringiensisinsecticidal crystal proteins

Jeroen Van RieBaltasar EscricheYolanda BelJuan Ferré

subject

GeneticsBacillaceaebiologymedia_common.quotation_subjectInsectbiology.organism_classificationMicrobiologyMajor geneBacillalesBiochemistryBacillus thuringiensisGeneticsBinding siteMolecular BiologyGeneBacteriamedia_common

description

Current knowledge of biochemical mechanisms of insect resistance to Bacillus thuringiensis is reviewed. Available information on resistance inheritance and on patterns of cross-resistance is included. Modification of the binding sites for B. thuringiensis insecticidal crystal proteins has been found in different populations of three insect species. This resistance mechanism seems to be inherited as a single recessive or partially recessive major gene, and the resistance levels reached are high. Altered proteolytic processing of B. thuringiensis crystal proteins has been suggested to be involved in one case of resistance. From the available data it seems that binding site modification is the most significant resistance mechanism under field conditions.

https://doi.org/10.1111/j.1574-6968.1995.tb07802.x