3-Oxo-rhazinilam: A New Indole Alkaloid from Rauvolfia serpentina × Rhazya stricta Hybrid Plant Cell Cultures

6533b7d0fe1ef96bd125a5d5

RESEARCH PRODUCT

3-Oxo-rhazinilam: A New Indole Alkaloid from Rauvolfia serpentina × Rhazya stricta Hybrid Plant Cell Cultures

Joachim Stöckigt Y. V. Sheludko Irina Gerasimenko

subject

Magnetic Resonance Spectroscopy Lactams Pharmaceutical Science Pharmacognosy Rhazya stricta Rhazinilam Mass Spectrometry Rauwolfia Analytical Chemistry chemistry.chemical_compound Alkaloids Rauvolfia serpentina Drug Discovery Botany Cells Cultured Pharmacology Plants Medicinal Indole alkaloid biology Apocynaceae Organic Chemistry Indolizines biology.organism_classification Coculture Techniques Terpenoid Somatic fusion Complementary and alternative medicine chemistry Molecular Medicine Spectrophotometry Ultraviolet

description

A new monoterpenoid indole alkaloid, 3-oxo-rhazinilam (1), was isolated from intergeneric somatic hybrid cell cultures of Rauvolfia serpentina and Rhazya stricta, and the structure was determined by detailed 1D and 2D NMR analysis. It was also proved that 3-oxo-rhazinilam (1) is a natural constituent of the hybrid cells.

year	journal	country	edition	language
2000-12-09	Journal of Natural Products

https://doi.org/10.1021/np000319x

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