Swift light sheet volumetric charting of large human brain portions

6533b7d0fe1ef96bd125ad4f

RESEARCH PRODUCT

Swift light sheet volumetric charting of large human brain portions

Giuseppe Sancataldo Giacomo Mazzamuto Ludovico Silvestri Annunziatina Laurino Francesco S. Pavone Matteo Roffilli Marina Scardigli Luca Pesce Vladislav Gavryusev Irene Costantini

subject

0303 health sciences education.field_of_study Materials science biology Population Human brain 01 natural sciences Fluorescence 010309 optics 03 medical and health sciences medicine.anatomical_structure nervous system Light sheet fluorescence microscopy 0103 physical sciences biology.protein Fluorescence microscope medicine NeuN Image sensor education light sheet brain imaging 030304 developmental biology Biomedical engineering

description

Using a custom light sheet fluorescence microscope, we image large stained human brain portions, labelled for NeuN and GAD67 neuronal markers, discerning the inhibitory population via neural-network based image analysis and exposing the brain connectivity.

year	journal	country	edition	language
2020-01-01

http://www.scopus.com/inward/record.url?eid=2-s2.0-85091394217&partnerID=MN8TOARS

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