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RESEARCH PRODUCT
Lexical and conceptual components of stem completion priming in patients with Alzheimer's disease
Girolama Alessandra MarfiaMarco MauriGiovanni Augusto CarlesimoCarlo CaltagironePatrizia TurrizianiLucia Faddasubject
MaleDissociation (neuropsychology)Cognitive NeuroscienceConcept FormationWord processingRepetition primingExperimental and Cognitive PsychologyAssociationBehavioral NeuroscienceMemoryAlzheimer DiseasemedicineHumansMemory disorderIntramodal dispersionAgedAnalysis of VarianceAlzheimer's dementiaCrossmodalMiddle Agedmedicine.diseaseSemanticsRepetition primingAnalysis of Variance; Reading; Association; Humans; Alzheimer Disease; Aged; Mental Recall; Cognition Disorders; Semantics; Concept Formation; Speech Perception; Practice (Psychology); Cues; Case-Control Studies; Middle Aged; Female; MaleReadingPractice PsychologicalPractice (Psychology)Case-Control StudiesMental RecallSpeech PerceptionFemaleSettore MED/26 - NeurologiaImplicit memoryCuesPsychologyCognition DisordersPriming (psychology)Cognitive psychologydescription
This study evaluated the hypothesis of dissociation between normal lexical but deficient conceptual repetition priming in patients with Alzheimer's disease (AD). For this purpose, we administered to patients with AD and age-matched normal controls the Stem Completion task. In Experiment 1, the level of word processing during study was manipulated by requiring subjects to count vowels (graphemic condition) or generate meanings (semantic condition) of target words. In Experiment 2, the presentation modality was varied during the study to obtain an intramodal and crossmodal repetition priming. Probably due to a floor effect of performance in the graphemic condition, in Experiment 1, AD patients exhibited lower priming than normal controls for the semantically processed words but comparable priming for the graphemically processed ones. In contrast, in Experiment 2, AD patients were poorly primed both in the intra- and crossmodal conditions. Results question the hypothesis of a lexical/conceptual dissociation in the repetition priming exhibited by AD patients and call for other explicative hypotheses of the dissociation between normal and deficient forms of repetition priming in degenerative dementia. Copyright (C) 1999 Elsevier Science Ltd.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1999-08-01 |