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RESEARCH PRODUCT
Predictive Value of Pro-BNP for Heart Failure Readmission after an Acute Coronary Syndrome
Julio NúñezMaría J MorenoElías Martínez Rey-rañalMaria A QuintanillaVicente Bertomeu-gonzalezDavid EscribanoPilar ZuazolaJosé Moreno-arribasAlberto Corderosubject
medicine.medical_specialtyAcute coronary syndromemedicine.medical_treatmentheart failurelcsh:Medicine030204 cardiovascular system & hematologyRevascularizationArticleacute coronary syndrome03 medical and health sciences0302 clinical medicineInternal medicineDiabetes mellitusmedicine030212 general & internal medicinecardiovascular diseasesbiologybusiness.industryIncidence (epidemiology)lcsh:RGeneral Medicinemedicine.diseaseTroponinHeart failureRelative riskbiology.proteinCardiologyBiomarker (medicine)businesspro-BNPdescription
Background: N-terminal pro-brain natural peptide (NT-pro-BNP) is a well-established biomarker of tissue congestion and has prognostic value in patients with heart failure (HF). Nonetheless, there is scarce evidence on its predictive capacity for HF re-admission after an acute coronary syndrome (ACS). We performed a prospective, single-center study in all patients discharged after an ACS. HF re-admission was analyzed by competing risk regression, taking all-cause mortality as a competing event. Results are presented as sub-hazard ratios (sHR). Recurrent hospitalizations were tested by negative binomial regression, and results are presented as incidence risk ratio (IRR). Results: Of the 2133 included patients, 528 (24.8%) had HF during the ACS hospitalization, and their pro-BNP levels were higher (3220 pg/mL vs. 684.2 pg/mL
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-04-01 | Journal of Clinical Medicine |