ChemInform Abstract: Enantioselective Synthesis of 2-Isoxazolines by a One-Flask Conjugate Addition/Oxime-Transfer Process.

6533b7d1fe1ef96bd125cbcf

RESEARCH PRODUCT

ChemInform Abstract: Enantioselective Synthesis of 2-Isoxazolines by a One-Flask Conjugate Addition/Oxime-Transfer Process.

subject

chemistry.chemical_compound chemistry Intramolecular force Organocatalysis Enantioselective synthesis General Medicine Oxime Combinatorial chemistry Catalysis Conjugate

description

Enantioselective isoxazoline synthesis: A combination of 1) a catalytic enantioselective conjugate addition of oximes to alpha,beta-unsaturated aldehydes and 2) an acid-catalyzed intramolecular oxime-transfer reaction lead to the first asymmetric synthesis of 3-unsubstituted 2-isoxazolines (see scheme).

year	journal	country	edition	language
2009-08-25	ChemInform

https://doi.org/10.1002/chin.200934126

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