6533b7d1fe1ef96bd125cc0b
RESEARCH PRODUCT
Is kidney a new organ target in patients with obstructive sleep apnea? Research priorities in a rapidly evolving field.
Maria R. BonsignoreAthanasios VoulgarisSophia E. SchizaOreste MarronePaschalis Steiropoulossubject
medicine.medical_specialtyPolysomnographyRenal functionDiseasePositive airway pressureSettore MED/10 - Malattie Dell'Apparato Respiratoriourologic and male genital diseasesKidneyEnd stage renal diseaseEnd-stage renal diseaseChronic kidney diseasePositive airway pressureEpidemiologymedicineHumansSleep-disordered breathingIntensive care medicineSleep Apnea Obstructivebusiness.industryResearchGeneral Medicinemedicine.diseaseObstructive sleep apneafemale genital diseases and pregnancy complicationsrespiratory tract diseasesNatural historyObstructive sleep apneaKidney Failure ChronicbusinessKidney diseasedescription
Abstract The bidirectional relationship between sleep disordered breathing and chronic kidney disease (CKD) has recently gained a lot of interest. Several lines of evidence suggest the high prevalence of coexistent obstructive sleep apnea (OSA) in patients with CKD and end-stage renal disease (ESRD). In addition, OSA seems to result in loss of kidney function in some patients, especially in those with cardio-metabolic comorbidities. Treatment of CKD/ESRD and OSA can alter the natural history of each other; still better phenotyping with selection of appropriate treatment approaches is urgently needed. The aim of this narrative review is to provide an update of recent studies on epidemiological associations, pathophysiological interactions, and management of patients with OSA and CKD or ESRD.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-10-01 | Sleep medicine |