6533b7d1fe1ef96bd125cda5
RESEARCH PRODUCT
In-hospital death according to dementia diagnosis in acutely ill elderly patients: the REPOSI study.
A MarengoniS CorraoA NobiliM TettamantiL PasinaF SalernoA IorioM MarcucciF BonomettiPm MannucciA Simi Investigators TedeschiR RossioG MoreoB FerrariA MammarellaV RaparelliS RondinellaI GiannicoL RascitiS GualandiV MonzaniV SavojardoG FabioS ColomboA QuercioliA BarrecaE Durante-mangoniD PintoE IncasaE RizzioliM VanoliG CasellaG MuscaO CuccurulloG FamularoMr SajevaA PicardiD HilaR RozziniA GiordanoA BonelliG DentamaroG GobboM CazzanigaP GaudenziL GiustoD RizzoniL CastoldiD MariG MicaleE AltomareG ServiddioC LonghiniC MolinoS DeiddaLm CuccuruM QuaglioloGr CentenaroAl PasquiL PuccettiG BertolinoP CavalloD BertoliniNl LiberatoA PerciaccanteA CoralliL AnastasioL BertucciG AgnelliA MacuraC MorabitoR FavaA TuttolomondoR Di SciaccaL MacchiniA RealdiA FiorentiniC TofiC CagnoniA ManucraG RomanelliM CortellaroMr MeroniDp RossiC VerganiD MariG Ogliarisubject
Malemedicine.medical_specialtyPediatricsSettore MED/09 - Medicina InternaMEDLINECharlson indexLogistic regressionNOolder patientSex FactorsAcute illnesses Dementia Hospitalization Mortality Older patientsmental disordersmedicineDementiaHumansDementia diagnosisHospital MortalityIntensive care medicineAgedIn hospital deathAged 80 and overbusiness.industryacute illnessesConfoundingAge Factorsrisk of deathmedicine.diseaseSettore MED/45 - Scienze Infermieristiche Generali Cliniche E Pediatrichemortalityolder patientsacute illnessePsychiatry and Mental healthPneumoniahospital admissionLogistic ModelsAcute DiseaseDementiaFemaleGeriatrics and Gerontologybusinessdementia; risk of death; hospital admissionhospitalizationdescription
The aim of the study was to explore the association of dementia with in-hospital OBJECTIVE:The aim of the study was to explore the association of dementia with in-hospital death in acutely ill medical patients. METHODS: Thirty-four internal medicine and 4 geriatric wards in Italy participated in the Registro Politerapie SIMI-REPOSI-study during 2008. One thousand three hundred and thirty two in-patients aged 65 years or older were enrolled. Logistic regression models were used to evaluate the association of dementia with in-hospital death. Socio-demographic characteristics, morbidity (single diseases and the Charlson Index), number of drugs, and adverse clinical events during hospitalization were considered as potential confounders. RESULTS: One hundred and seventeen participants were diagnosed as being affected by dementia. Patients with dementia were more likely to be women, older, to have cerebrovascular diseases, pneumonia, and a higher number of adverse clinical events during hospitalization. The percentage of patients affected by dementia who died during hospitalization was higher than that of patients without dementia (9.4 versus 4.9%). After multiadjustment, the diagnosis of dementia was associated with in-hospital death (OR = 2.1; 95% CI = 1.0-4.5). Having dementia and at least one adverse clinical event during hospitalization showed an additive effect on in-hospital mortality (OR = 20.7; 95% CI = 6.9-61.9). CONCLUSIONS: Acutely ill elderly patients affected by dementia are more likely to die shortly after hospital admission. Having dementia and adverse clinical events during hospital stay increases the risk of death.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-01-01 | International journal of geriatric psychiatry |